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H W Radeke

Publications and source records attributed to H W Radeke.

5 recordsLinked to original sources

Value of intravesical sonography in tumor classification of bladder carcinoma.

The possibility of a T classification for bladder carcinoma by intravesical sonography was investigated in a 3-year field study (1982-1985) at the Urological Clinic, Bonn University. In a total of 571 patients with histologically verified bladder cancer, the sonographic classification was compared with the histological T category. There was an agreement of 70.1%. While the infiltration of superficial tumors (above all of large tumors) was frequently overestimated (28.7%), understaging predominated in invasive carcinomas (20.9%). The overall precision of conventional staging techniques was 67%. Ultrasonography showed a marked superiority, above all in infiltrative papillary tumors of low diameter (precision 76% compared to 12% with the conventional T classification). The sensitivity of the method with regard to the detection of tumor infiltration (90%) was also markedly higher than that of earlier techniques (66%). Particularly helpful in the evaluation of more deeply infiltrating tumors, intravesical sonography constitutes a major extension of the diagnostic spectrum for T classification of bladder carcinoma.

Aged↗

[Experimental studies on intracavitary sonography].

In intravesical sonography artificial reflexes often lead to optical misinterpretation and mistaken diagnosis. In several experiments we followed up the ultrasound-capacity of dissolution and demonstrate different phenomena of reflexes. The findings are compared with intravesical and intrarectal sonograms; they are of use to interpret intracavitary B-Scan-Ultrasound.

Humans↗

[Diagnosis of urinary bladder cancer by transurethral sonography].

With 66.5% the total reliability of the transurethral sonography is significantly higher than that of all methods hitherto used. If one restricts oneself to the differentiation between muscle-invasive and superficial carcinomas the share of impacts is even 77.5%. Considering an error of nevertheless 33% and 23%, respectively, in the T-classification of the carcinoma of the urinary bladder the new method could, however, not fulfil the high expectations which were set into it at the beginning. Particularly a differentiation between mucosa and lamina propria as well as superficial and deep musculature is not possible. According to this the transurethral sonography is not suited as the only method for preoperative T-classification and basis of therapy planning. Difficulties appear above all in large and echo-dense carcinomas, respectively, as well as in pretreated urinary bladders. Consequently, a sufficient experience in the judgment of sonogrammes is necessary, in order to avoid wrong interpretations as to a tumor infiltration. Nevertheless, the transurethral sonography is an essential enlargement of the hitherto scanty spectre of the T-classification of the carcinoma of the urinary bladder. Supplementing the computer tomogram, the method brings the operator a quick survey of a possible infiltration of the wall of the bladder and a perivesical growth of the tumour. In deeply infiltrating, not radically resectable carcinomas in many cases an extensive staging-TUR may thus be avoided.

Humans↗

[The pathologic urinary bladder in the sonographic image].

Intracavitary sonography proved to be advantageous with regard to the T-classification of urinary bladder tumours in comparison with conventional diagnostic methods. Besides the good practicability, the high degree of correspondence between sonography and histopathological findings is emphasized. In 97 patients with urothelial bladder cancer this method yielded 63% correct results. In 32% overstaging was noticed, possible factors of which were exemplified. Part of the sonographic failures can be avoided by means of technical manipulation (gain-modification) together with increasing experience of the examiner. In particular benign bladder disease, which can be sonographically confused with cancer, has to be considered. These cases indicate the need to correlate particular sonographic findings with histopathology.

Cystitis↗