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H W Ratledge

Publications and source records attributed to H W Ratledge.

4 recordsLinked to original sources
PubMed1986

Split course pelvic irradiation and a boost for carcinoma of the prostate.

Fifty nine patients with prostatic cancer treated by definitive external irradiation were retrospectively evaluated. The true pelvis and prostate gland were irradiated by a split course technique for 48-50 Gy and 68-70 Gy in 7 weeks with a booster dose of 20 Gy delivered in the rest period (after 24-26 Gy) to the prostate via small ports. The overall 3 and 5 year actuarial survival was 83% and 75%, respectively. Only four patients had persistent local disease and two of these (Stage D) died with local disease and distant metastases. Acute mild diarrhea or mild cystitis occurred in 26 patients whereas two patients developed chronic diarrhea lasting for 2 and 12 months after therapy. There were no long-term complications requiring interventional surgery. Sexual potency did not seem to be affected. These results indicate that carefully performed external radiotherapy with a booster dose delivered half-way through whole pelvic radiation is very well tolerated without affecting the local control rate.

Aged↗
PubMed1978

Deep venous thrombosis following transurethral resection of the prostate: diagnosis by phleborheography.

Deep venous thrombosis is a potential complication of transurethral resection of the prostate. We evaluated 150 paients undergoing transurethral resection of the prostate for benign and malignant disease to determine the postoperative incidence of deep vein thrombosis, using phleborheography as the instrument of detection. Phleborheography is an accurate, inexpensive, non-invasive method that uses low pressure transducers to detect volumetric changes in the lower extremity through recording cuffs. A 4.6 per cent incidence of deep venous thrombosis was detected by this technique. At the time this complication was discovered no patient exhibited clinical signs of thrombophlebitis, which reinforces the belief that clinical diagnosis alone is not a reliable screening technique for deep venous thrombosis. Anticoagulant therapy appears to be effective and safe in the treatment of this postoperative complication.

Adenocarcinoma↗