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Biomedical subjects

H W Roth

Publications and source records attributed to H W Roth.

24 records · Page 2Linked to original sources
PubMed1978

[Fungal growth on soft contact lenses (author's transl)].

The relevance of fungal contamination of soft contact lenses is demonstrated by own clinical observations in 25 cases. It can be shown by surface-microscopical, histological and mycological analysis, that various fungi can not only grow on the surface of HEMA-lenses, but can also invade the material. The efficacy of chemical disinfectants, as tested against two of the isolated fungi seems to be inferior to that of heat sterilisation. The resulting fundamentally and clinically important consequences, especially concerning permanent wear of hydrophilic contact lenses, are discussed.

Contact Lenses, Hydrophilic↗
PubMed1977

[Orthokeratology. Technique - possibilities - limits (author's transl)].

The vornea is because of its refraction, its structure and accessibility the easiest variable component of the optic eye system. Flat fitted, barely flexible contact lenses exercise by their small central clearance a considerable pressure on the corneal apex and will therefore bring about a reversible clearance of the central corneal topography. Orthokeratology therapeutically uses this effect in order to temporarily reducing, changing or eliminating a refractive error. This is of a particular interest in the case of a keratoconus. Orthokeratology is not without danger because too high pressures have a weekening effect on the corneal trophic and resistance.

Contact Lenses↗
PubMed1975

[Aqueous humor pH in experimental lye burns and influence of different treatment measures (author's transl)].

300 rabbit corneas were burned for 1 minute by applying a filter paper of 10 mm diameter soaked in different concentrations of NaOH. The aqueous humor pH was then measured at certain time intervals and after different treatment methods until the physiologic pH of 7.6 was reached. The results were statistically analysed. Group 1, 2 and 3 were burned in 1n NaOH, 3n NaOH, and 6n NaOH respectively without any treatment. In these groups a "therapeutic" pH-level of 8.5 was measured on an average 0.5, 2.5 and 5 hours after the burn (Table 1 and Fig. 2). Group 4 and 5 again were burned with 6n NaOH. In group 4 the burn was followed by constant irrigation with physiologic saline solution by means of the Morgan Therapeutic Lens (Fig. 1a and b). With this regimen a pH of 8.5 was reached after 2.5 hours (Table 1 and Fig. 3). In group 5 the physiologic saline solutions was replaced by a buffer solution (Isogutt) and a pH of 8.5 was measured after only one hour (Table 1 and Fig. 3). Based upon these results it is felt that severe lye burns should be treated by constant irrigation with a buffer solution for several hours. A treatment that can easily be performed by use of the Morgan Therapeutic Lens.

Animals↗