Biomedical subjects

H Yüksek

Publications and source records attributed to H Yüksek.

2 recordsLinked to original sources

PubMed1997

Synthesis and antibacterial activities of some 4,5-dihydro-1H-1,2,4-triazol-5-ones.

Twenty-one new 1-methyl- and 1-ethyl-3,4-disubstituted-4,5-dihydro- 1H-1,2,4-triazol-5-ones were synthesized and characterised by elemental analysis, 1H-NMR and IR spectra. These new and 16 recently reported derivatives of 4,5-dihydro-1H-1,2,4-triazol-5-one ring were screened for their antibacterial activities.

Anti-Bacterial Agents↗

PubMedDate not supplied

A study on ester thiosemicarbazones.

The cyclization of ester thiosemicarbazones to two different heterocycles was studied for some new thiosemicarbazones, and only the formation of 1,2,4-triazol-5-thiols was attributed to the regioselectivity of the ring closure reaction, due to a steric hindrance of bulky groups. Next, some of the new compounds were tested for their in vitro antimicrobial and antitumor activities.

Antibiotics, Antitubercular↗