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Biomedical subjects

H Yonehara

Publications and source records attributed to H Yonehara.

At least 19 recordsLinked to original sources

Radon concentrations in residential housing in Hiroshima and Nagasaki.

A measurement of indoor radon (222Rn) concentrations in Hiroshima and Nagasaki was carried out to assess the variability of exposure expected among atomic bomb survivors. Two hundred dwellings, mostly belonging to members of the fixed cohort of atomic bomb survivors under study by the Radiation Effects Research Foundations, were selected for this measurement. The geometric mean values of the radon concentrations for 100 dwellings in Hiroshima and 99 dwellings in Nagasaki measured by Track-Etch Type SF detectors were 56.8 Bq m-3 and 28.5 Bq m-3, respectively. No statistically significant difference was observed between lung cancer mortalities in the low-dose range in the two cities. However, apparent values of the mortality rate for low dose range in Hiroshima are consistently greater than those in Nagasaki. The exposure to radon and its progeny and the atomic bomb radiation effect might have some cooperative effects on the lung cancer incidence.

Air Pollutants, Radioactive

Prefabricated venous flaps: an experimental study in rabbits.

Prefabrication is a method for creating donor flaps by implantation of a nourishing pedicle prior to harvesting the flap. Based on the concept that implantation of a "flow-through" vein results in sufficient vascularisation to support a skin flap, we used a rabbit model to investigate the viability of prefabricated total venous perfusion (TVP) flaps. Prefabrication of an abdominal wall donor site was performed using the left epigastric vein in 25 male New Zealand white rabbits. An 8 x 10 cm skin flap was elevated 1, 2, 3, 4, and 6 weeks after prefabrication (n = 5 per group). A silicone sheet was implanted under the skin flap. The mean survival rate of skin flaps was 24%, 52%, 87%, 83%, 84%, respectively. Results of this study show that reproducible survival of a prefabricated TVP flap can be obtained when the flap is elevated more than 3 weeks after prefabrication.

Abdominal Muscles

The chemistry of actinocarcin. I. Further characterization and C-terminal structure of actinocarcin.

The amino-acid composition and molecular weight of actinocarcin, and C-terminal structure of actinocarcin are reported in this paper. By STEIN-MOORE'S and ultraviolet-absorption methods, the molar ratio of amino acids in actinocarcin was determined. The N-terminal amino acids are alanine and valine. The C-terminal amino acid, determined by hydrazinolysis, is tryptophan. The molecular weight is about 11,000 as estimated by ARCHIBALD'S method and amino acid analysis. Three fragments, named BrCN-I, BrCN-II and BrCN-III, were obtained by cyanogen bromide cleavage. The structure of BrCN-III, namely the C-terminal structure of actinocarcin was determined by EDMAN degradation.

Amino Acids

Deisovalerylblastmycin produced by Streptomyces SP.

A new antifungal antibiotic was isolated from the fermentation broth of Streptomyces sp. 5140-A1. Degradation studies of the crystalline antibiotic, m.p. 186 approximately 188 degrees C, C21H28O8N2, suggested Piricularia oryzae and less toxicity against killfish than antimycin A--blastmycin antibiotics.

Animals