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Biomedical subjects

H Z Tan

Publications and source records attributed to H Z Tan.

10 recordsLinked to original sources

The effect of a disastrous flood on the quality of life in Dongting lake area in China.

We carried out an epidemiological study to assess the impact of flood on the quality of life (QOL) of residents in the affected areas in China. We used a natural experiment approach, randomly selected 494 adults from 18 villages, which suffered from flooding as a result of embankments collapsing, 473 adults from 16 villages, which suffered from, soaked flood, and 773 adults from 11 villages without flood (control group). We used the Generic QOL Inventory-74 (GQOLI-74), social support scale, and questionnaires to assess the QOL of all study participants. The QOL was significantly poorer in soaked group (58.4) and (especially) in collapsed group (55.1) than in control group (59.5, p<0.001). Adjustment for potential confounding factors did not change the results. The impact of flood on QOL was stronger among farmers, seniors, persons with introvert personality, and residents with adverse life-events, whereas social support and extrovert personalities offset the negative impact of flood on QOL.

Adult↗

[Research on mental health status of 726 adolescents and its influential factors].

Mental health status of 726 adolescents and their backgrounds were investigated with Symptom Check List(SCL-90) and self-designed questionnaire. The results showed that the prevalence rate of psychological problems ranged from 6.34% to 24.93%. Among these problems, obsession led all the others. Females had higher scores in interpersonal sensitivity, depression, anxiety, phobia than males. Logistic regression analysis indicated that the major factors contributed to mental health status of adolescents were the relationship between teacher and student, father's concern with his child, only child or not, parents' expectations, personality and sex. The study provides reference source for improving the mental health status of adolescents.

Adolescent↗

Information transmission with a multifinger tactual display.

In this work, the tactual information transmission capabilities of a tactual display designed to provide stimulation along a continuum from kinesthetic movements to cutaneous vibrations are assessed. The display is capable of delivering arbitrary waveforms to three digits (thumb, index, and middle finger) within an amplitude range from absolute detection threshold to about 50 dB sensation level and a frequency range from dc to above 300 Hz. Stimulus sets were designed at each of three signal durations (125, 250, and 500 msec) by combining salient attributes, such as frequency (further divided into low, middle, and high regions), amplitude, direction of motion, and finger location. Estimated static information transfer (IT) was 6.5 bits at 500 msec, 6.4 bits at 250 msec, and 5.6 bits at 125 msec. Estimates of IT rate were derived from identification experiments in which the subject's task was to identify the middle stimulus in a sequence of three stimuli randomly selected from a given stimulus set. On the basis of the extrapolations from these IT measurements to continuous streams, the IT rate was estimated to be about 12 bits/sec, which is roughly the same as that achieved by Tadoma users in tactual speech communication.

Communication Devices for People with Disabilities↗

Reception of Morse code through motional, vibrotactile, and auditory stimulation.

The potential for communication through the kinesthetic aspect of the tactual sense was examined in a series of experiments employing Morse code signals. Experienced and inexperienced Morse code operators were trained to identify Morse code signals that were delivered as sequences of motional stimulation through up-down displacements (roughly 10 mm) of the fingertip. Performance on this task was compared with that obtained for both vibrotactile and acoustic presentation of Morse code using a 200-Hz tone delivered either to the fingertip through a minishaker or diotically to the two ears under headphones. For all three modalities, the ability to receive Morse code was examined as a function of presentation rate for tasks including identification of single letters, random three-letter sequences, common words, and sentences. Equivalent word-rate measures (i.e., product of percent correct scores and stimulus presentation rate) were nearly twice as high for auditory presentation as for vibrotactile stimulation, which in turn was about 1.3 times that for motional stimulation. The experienced subjects outperformed the inexperienced subjects by amounts that increased with task complexity. For example, the former were able to receive sentences at 18 words/min with motional stimulation, whereas the latter, following 75 h of training, were unable to perform this task. The present results and those of other research with tactual communication systems are compared, particularly regarding estimates of information-transfer rates.

Acoustic Stimulation↗

Information transmission with a multi-finger tactual display.

Motivated by the highly successful Tadoma method of speech communication, a multi-finger positional display (the TACTUATOR) was developed to study perception via the kinesthetic and vibrotactile aspects of the tactual sensory system of the hand. The information transmission capabilities with the TACTUATOR were assessed through a series of absolute identification experiments. An information transfer (IT) of 5.6 to 6.5 bits for stimulus durations of 125 to 500 msec was obtained in absolute-identification experiments with sets of signals derived by varying frequency, amplitude, and site of stimulation of multicomponent waveforms. An estimated IT rate of 12 bits/sec was obtained by sequencing three random stimuli and (a) having the subject identify only the middle stimulus and (b) extrapolating this IT to that for continuous streams. This IT rate is roughly the same as that achieved by Tadoma users in tactual speech communication.

Adult↗

Manual discrimination of compliance using active pinch grasp: the roles of force and work cues.

In these experiments, two plates were grasped between the thumb and the index finger and squeezed together along a linear track. The force resisting the squeeze, produced by an electromechanical system under computer control, was programmed to be either constant (in the case of the force discrimination experiments) or linearly increasing (in the case of the compliance discrimination experiments) over the squeezing displacement. After completing a set of basic psychophysical experiments on compliance resolution (Experiment 1), we performed further experiments to investigate whether work and/or terminal-force cues played a role in compliance discrimination. In Experiment 2, compliance and force discrimination experiments were conducted with a roving-displacement paradigm to dissociate work cues (and terminal-force cues for the compliance experiments) from compliance and force cues, respectively. The effect of trial-by-trial feedback on response strategy was also investigated. In Experiment 3, compliance discrimination experiments were conducted with work cues totally eliminated and terminal-force cues greatly reduced. Our results suggest that people tend to use mechanical work and force cues for compliance discrimination. When work and terminal-force cues were dissociated from compliance cues, compliance resolution was poor (22%) relative to force and length resolution. When work cues were totally eliminated, performance could be predicted from terminal-force cues. A parsimonious description of all data from the compliance experiments is that subjects discriminated compliance on the basis of terminal force.

Adult↗

Manual discrimination of force using active finger motion.

In these experiments, two plates were grasped between the thumb and forefinger and squeezed together along a linear track. An electromechanical system presented a constant resistance force during the squeeze up to a predetermined location on the track, whereupon the force effectively went to infinity (simulating a wall) or to zero (simulating a cliff). The task of the subject was to discriminate between two alternative levels of the constant resistance force (a reference level and a reference-plus-increment level). Results of these experiments indicate a just noticeable difference of roughly 7% of the reference force using a one-interval paradigm with trial-by-trial feedback over the ranges 2.5 less than or equal to F0 less than or equal to 10.0 newtons, 5 less than or equal to D less than or equal to 30 mm, 45 less than or equal to S less than or equal to 125 mm, and 25 less than or equal to V less than or equal to 160 mm/sec, where F0 is the reference force, D is the distance squeezed, S is the initial fingerspan, and V is the mean velocity of the squeeze. These results, based on tests with 5 subjects, are consistent with a wide range of previous results, some of which are associated with other body surfaces and muscle systems and many of which were obtained with different psychophysical methods.

Biomechanical Phenomena↗

Analysis of a synthetic Tadoma system as a multidimensional tactile display.

The Tadoma method is a means of speech reception based on tactile monitoring of the articulatory process. A "synthetic" Tadoma system, involving an artificial face with six facial actions, has been developed as a first-order approximation to the natural Tadoma system. Experiments were conducted to explore the information-transmission characteristics of the synthetic Tadoma system in terms of the four facial movements it incorporates: upper lip in-out, lower lip in-out, lower lip up-down, and jaw up-down movements. Discrimination experiments showed that the just-noticeable difference associated with each movement is about 9% of the reference displacement. One-dimensional (1-D) absolute identification experiments produced, on the average, 1.6 bits of information transfer. Four dimensional (4-D) identification experiments produced information transfers in the range of 3-4 bits. Of the four dimensions considered, performance on the lower lip up-down movement was most affected, and performance on the jaw up-down movement was least affected, by simultaneous roving movements on the other dimensions. As a result of the interaction among the movement channels, the sum of the 1-D information transfers exceeds the 4-D information transfer. However, the sum of the 1-D information transfers obtained from tests with roving parameters is approximately equal to the 4-D information transfer (possibly exemplifying a "generalized information-transfer additivity law"). In general, both the discrimination and identification results appear unexceptional and, hence, the reception of facial movement information by itself does not appear to account for the extraordinary success of the Tadoma method.

Humans↗

[Family clustering analysis of HBV infection].

A family clustering analysis of HBsAg, anti-HBs, anti-HBc positive and total infected persons in 148 families on a farm was carried out by the methods of G statistic, binomial distribution and negative binomial distribution. The results consistently showed that there was significant clustering of HBsAg carriers in families, whereas there were not clustering was seen an overall HBV infected persons in families. The clustering of HBsAg carriers in families is due probably to the effect of some genetic factors. The results of G statistic analysis indicate that anti-HBc also have significant clustering in families.

Carrier State↗