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Biomedical subjects

H Zídková

Publications and source records attributed to H Zídková.

At least 19 recordsLinked to original sources
PubMed1993

[Herniation pits].

"Herniation pit" is a benign bone affection described first in 1982 by Michael J. Pitt et al. It is located typically in the proximal anterior and upper quadrant of the neck of the femur and develops as a result of the mechanical action of pressure of the adjacent articular capsule and synovialis. On the X-ray picture it is seen as a lighter spot which is relatively well defined, surrounded by a narrow margin of sclerotic bone; it is either round or oval and usually not more than 1 cm in diameter. In the authors' group of 100 patients selected at random from patients who had an X-ray picture of the hip joint taken during the last three years for different indications a herniation pit was found in six patients--4 women and 2 men. In one patient the finding was bilateral. This result is practically consistent with the 5% in the normal adult population, as reported in the world literature. In clinical practice the herniation pit is in the majority asymptomatic and is only an incidental finding during X-ray examination of patients with unexplained pain in the hip joint. Its importance is thus above all that it may be mistaken for other usually oncological bone affections such as osteoid, osteoma, Brodie's abscess, intraosseous ganglion or skeletal metastases of carcinoma.

Adult↗
PubMed1993

[Aggressive fibromatosis in the extremities].

The authors demonstrate in a group of 10 patients treated in the course of 15 years the rare incidence of aggressive fibromatosis of the extremities and the large number of relapses after surgery. They also emphasize the necessity of detailed preoperative examination, priority of a surgical approach, as compared with radiotherapeutic procedures, and the possibility of skeletal and vascular reconstruction after radical surgery.

Adult↗
PubMed1993

[Aggressive chondroblastoma].

The authors report three observations of rather extensive aggressive chondroblastoma and draw attention to difficulties of histological diagnosis, which result out of a less typical histological picture, in which signs of differentiation into cartilaginous tissue may be missing. Differential diagnosis may be facilitated by proper recognition of the cytologic character of chondroblasts by the positivity of S-100 protein, and by proving characteristic properties of chondroblasts in electronmicroscopic examination. In treating this type of tumors an increased risk of local recurrence (in one of our patients) and aggressive behaviour to surrounding tissues should be considered, exceptionally pulmonary metastases may develop, as was the case in one of our presented patients.

Adult↗
PubMed1990

Digital subtraction angiography in musculoskeletal tumors and other conditions.

One hundred and forty consecutive DSA examinations of various musculoskeletal diseases were analyzed with respect to the contributions and/or limits of this modern diagnostic imaging modality. Angiography remains the imaging tool of choice for many benign and malignant orthopedic conditions of bones and soft tissues, mainly when MRI is still not generally available. It remains indispensable for embolization and/or local chemotherapy. DSA has the advantage of being less invasive and it also surpasses analog arteriography in better visualization of vascular patterns hidden in hyperostosis, sclerosis, and metallic shadows. Angiographic investigations, when necessary, should therefore start with DSA.

Adolescent↗
PubMed1990

[Extensive metastases of Ewing's sarcoma in the adreno-renal area].

The authors refer to the observation of 43 years old woman with Ewing's sarcoma of the pelvic region, who displayed, a year after local extirpation of the tumour, clinically and radiographically, a metastasis in the adrenal-renal region. The patient died due to generalization of the tumour during the next year after an attempt to remove the metastasis, where a radical intervention proved impossible. Metastases of malignant tumours of locomotor apparatus into this region proved to be rare and such is the observation of the extensive affection in the Ewing's sarcoma.

Adrenal Gland Neoplasms↗
PubMed1989

Periosteal Ewing's sarcoma.

Periosteal Ewing's sarcoma is an uncommon, but well documented origin of this malignant condition with radiographic signs, different from intramedullary growing tumours. Imaging modalities like CT or MRI supply proof of macroscopically intact endosteal cortical surface and free medullary cavity in long bones affected by this periosteal type of malignancy. Definite confirmation is valid after a careful microscopic investigation of the resected specimen. The prognosis of this type of Ewing's sarcoma may be more favourable than that of the central type. Early diagnosis and therapy are thus essential. A clinical survey of six observations is given.

Bone Neoplasms↗
PubMed1989

[Extramedullary Ewing's sarcoma].

The authors refer to six observations of periostal Ewing's sarcoma and describe its X-ray symptomatology. It differs considerably from the commonly known picture of centrally, intramedullar-originated Ewing sarcomas and tumours, diagnosed at considerable advanced stage. The possibility of periosteal origin of Ewing's sarcoma must be considered in differential diagnosis of periostoses and the patients must be examined in a complex way, particularly by computer tomography (and in the future also by MR tomography) in order to demonstrate that the medullar space of the bone is not affected by the tumour. This enables a more considerate resection during the operation. Histological verification of the nature of the tumour and excluding presence of the tumour cells in bone marrow dissection material is necessary. It may be expected that prognosis of this form of Ewing's sarcoma while treated in a modern combined way is more favourable than in the central forms.

Adolescent↗
PubMed1988

Osteosarcoma with a clear-cell component.

The reports concerns the light microscopical and ultrastructural findings obtained in three conventional osteosarcomas with an unusually high admixture of clear cells, whose presence appeared to be responsible for the marked change in the histological pattern of these tumours. In the tumours with a prevailing fibroblastic component the clear cells were either irregularly scattered throughout the tumour in the form of small groups, or they formed large groups sharply demarcated against the fusicellular areas of the tumours. In two cases it was shown that their cytoplasm contained exaggerated glycogen deposits accompanied by the formation of glycogen-containing phagolysosomes and occasional empty vacuoles. In the third case the clear cells showed vacuolar degeneration with numerous single-membrane-bound, empty vacuoles. In contrast to the clear-cell chondrosarcoma we did not find S-100 protein in clear cells of our osteosarcomas. Such findings could be particularly significant in the differential diagnosis of bone tumours.

Adolescent↗