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Biomedical subjects

H Zieliński

Publications and source records attributed to H Zieliński.

At least 19 recordsLinked to original sources
PubMed2000

Antioxidant activity and total phenolics in selected cereal grains and their different morphological fractions.

The purpose of this study was to examine the antioxidant properties of water and 80% methanolic extracts of cereal grains and their different morphological fractions. Wheat (Triticum aestivum L.) cv. Almari and cv. Henika, barley (Hordeum vulgare L.) cv. Gregor and cv. Mobek, rye (Secale cereale L.) cv. Dańkowskie Zlote, oat (Avena sativa L.) cv. Slawko and buckwheat (Fagopyrum esculentum Moench) cv. Kora were used. PC (L-alpha-phosphatidylcholine) liposome system and spectrophotometric assay of total antioxidant activity (TAA) were used to evaluate the antioxidative activity of extracts. Among the water extracts, only the one prepared from buckwheat exhibited antioxidant activity at the concentration analyzed. The following hierarchy of antioxidant activity was provided for 80% methanolic extracts originated from whole grain: buckwheat > barley > oat > wheat congruent with rye. The antioxidant activity was observed in extract prepared from separated parts of buckwheat and barley. In respect to hulls, the antioxidant hierarchy was as follows: buckwheat > oat > barley. The correlation coefficient between total phenolic compounds and total antioxidative activity of the extracts was -0.35 for water extracts and 0.96, 0.99, 0.80, and 0.99 for 80% methanolic extracts originated from whole grains, hulls, pericarb with testa fractions and endosperm with embryo fractions, respectively.

Antioxidants↗
PubMed1999

[Oncologic risk of nerve sparing prostatectomy in patients with prostate cancer].

At the early 80-ties Walsh introduced nerve-sparing radical prostatectomy (NSRP) which includes sparing of neurovascular bundle. This allows persistence of erection following the surgery. Benefits from this improved technique are evident, nevertheless there exist a real threat of recurrencies due to not radical removal of tumorous tissues. The aim of the present paper is to assess the oncologic risk of NSRP in own material. During 1992-1997 a total of 39 radical prostatectomies (RP) were performed, 10 of them were NSRP. RP was in each case made by retropublical approach, according to Welsh. Of the 39 patients undergoing RP a normal sexual activity before surgery was declared by 26 (66.6%). In 14 patients with preserved sexual potency the neoplastic changes were limited to single lobe. Among 10 patients treated with NSRP in 3 the changes were found in both lobes, while in one of them the infiltration tended to invade along the neurovascular bundle. In 5 patients treated with NSRP erections were preserved. On base of obtained results it is concluded that NSRP is indicated only in patients with tumors localized only in one lobe of the prostate and preferably, at the early stage of tumour development. NSRP should be performed only in those patients, who before surgery declared no troubles with erections. Oncologic risk is higher in group with NSRP.

Aged↗
PubMed1999

[Results of surgical treatment of adrenal gland tumors: own 15-year long experience].

In the present communication we present the results of surgical treatment of tumours of the adrenal glands, basing on the material from our clinical department. During 1983-1997 at the Department of Clinical Urology Central Clinical Hospital of the Military University School of Medicine (CSK WAM) 27 patients (15 men, 12 women) with tumors of the adrenal glands were treated. Among the operated patients 3 were diagnosed with Cushing's syndrome, 3 with pheochromocytoma, 1 with Cohn's syndrome, while in the remaining 20 the tumours were hormonally inactive. Surgical treatment included 15 right, 10 left and 2 bilateral adrenalectomies. There was no intraoperational mortality. In all patients with hypersecretion, the symptoms disappeared after adrenalectomy. The size of tumours ranged 4-20 cm. In 3 patients there appeared a need for broadening of the size of surgical intervention--2 splenectomies and 2 nephrectomies and 1 resection of pancreatic tail--all due to regional infiltrations with tumorous tissues. During surgery there occurred 2 cases of iatrogenic pleuric injury. Postoperative complications included 1 case of pneumonia and 1 case of wound infection. In case of unilateral tumours of the adrenal glands the best method for surgery appears to be the lateral (lumbal) resection and in case of large tumours and/or bilateral tumours the most convenient appears to be the anterior (transperitoneal) resection. The most applicable method for diagnosis of tumours of the adrenal glands appears to be CT and NMR.

Adrenal Gland Neoplasms↗
PubMed1997

[Malignant lymphoma of both testes].

A patient with rare primary lymphoma of the testis is presented. Several investigators have reported the prognosis in the majority of patients was associated with a poor outcome. In our case poor prognostic factors and the presence of many symptoms, such as fever, night sweets or weight loss significant influenced on the prognosis and the length of disease free-survival in patient with testicular lymphoma.

Aged↗
PubMed1996

[Primary non-Hodgkin's lymphoma of the prostate].

A patient with a rare primary lymphoma of the prostate is presented. Clinical symptoms may be a reason of mistake, that are highly suggestive of benign prostatic hyperplasia or prostatic adenocarcinoma. Before treatment all patients should have to determined the histopathological diagnosis (made by prostatic biopsy or by prostatectomy) because treatment of patients with primary non-Hodgkin's lymphoma of the prostate is quite different then treatment of patients with prostatic adenocarcinoma. After treatment with combination chemotherapy appropriate for the clinical stage and the specific histological subtype our patient achieved a complete remission and remained free of disease after twelve months.

Adenocarcinoma↗
PubMed1992

The prognostic value of prostate-specific antigen and prostatic acid phosphatase in serum of patients with prostate cancer after orchidectomy.

Correlations between the serum levels of PAP and PSA before and 1, 3 and 6 months after orchidectomy in 27 prostatic cancer patients (advanced clinical stages C and D according to Whitemore scale) were studied. The PSA values correlated more distinctly than PAP with the general clinical condition. PSA is a reliable tumour marker when used at regular intervals, especially for monitoring therapeutic results. A high preoperative PSA level correlates with a high postoperative level and progression of the disease.

Acid Phosphatase↗
PubMed1991

[Nucleic acid levels in milk and blood of healthy cows and those with mastitis].

Investigations were carried out in 30 ncb breed cows divided into two groups. First group was consisted with cows in good health. In second group there were cows ill with mastitis. Number of somatic cells in milk was evaluated by California Mastitis Test and nucleic acids content in milk and blood by spectrophotometric method. Nucleic acids content in group of healthy cows amounted 273 micrograms/100 ml in milk and 0.114 g/100 ml in blood. In this group correlation factor concerning nucleic acids content in milk and blood amounted r = +0.57. In group ill cows nucleic acids content in milk and blood amounted respectively 500 micrograms/100 ml and 0.140 g/100 ml, and value of correlation factor r = -0.09 was noted. Differences in nucleic acids content in milk and blood between both groups healthy and ill cows correspond to values 227 micrograms/100 ml and 0.026 g/100 ml and were statistically significant by p less than 0.01. Above results allow to formulate the following conclusions: 1. Statistically high correlation between quality of somatic cells and nucleic acids content in milk exists--it is confirmation well known fact. 2. The rise of nucleic acids content in blood of cows can be an index of udder inflammation in cows.

Animals↗
PubMedDate not supplied

[Analysis of the incidence of sexually transmitted diseases in 1987].

In 1987 the number of cases of early symptomatic syphilis increased by 1.5% to 1211 cases (3.2 per 100 thousand). Early asymptomatic syphilis was diagnosed in 2.5 per 100 thousand of the population, that is 5% less than in the preceding year. In all, 2136 cases of early syphilis were recorded, that is 1% less than in the preceding year, and the incidence was 5.7 per 100 thousand. The incidence of gonorrhoea decreased by 23% to 7665 cases, that is 20.3 per 100 thousand, the lo-west incidence after World War II. The male/female sex ratio was 3.4:1. The incidence of non-gonococcal urethritis was 16% lower in men, that is 26.6 per 100 thousand of men. The ratio of NGU to gonorrhoea was 82:100. Anti-HIV antibodies were detected in 1987 in another 32 Polish citizens (since 1985 they were found in 52 Polish citizens) and 7 foreigners, 3 of whom left Poland. Homosexual and bisexual males prevailed (23), 14 were haemophiliacs, 9 were women (5 prostitutes). Two new cases of AIDS were found (three in all), all three patients died.

Acquired Immunodeficiency Syndrome↗