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Biomedical subjects

H Zirkin

Publications and source records attributed to H Zirkin.

At least 37 records · Page 2Linked to original sources
PubMed1989

Widespread oral papillomatosis due to chronic buccal trauma.

We present a case of oral papillomatosis occurring in a 52-year-old woman. This condition is well known and is characterized by an exuberant proliferation of multiple, flat, verruca-like elevations on the oral and pharyngeal mucosa. This is apparently the first documented case of oral papillomatosis due to trauma to the oral tissue from a dental prosthesis, with subsequent inflammation. Correction of the prosthesis resulted in marked improvement. This presentation emphasizes the causes, diagnosis, pathologic basis, and treatment of this condition.

Denture, Partial, Removable↗
PubMed1988

Benign nasopharyngeal lymphoid tumors, lymphoepithelial lesions, and lymphocytic interstitial pneumonitis.

A clinico-pathologic and immunologic case study of a 57-year-old woman who has shown progressive lymphoid proliferations and lymphocyte dysfunction over the course of 10 years is presented. Early in the course of her disease, she presented with recurrent benign nasopharyngeal lymphoid tumors. She subsequently developed benign lymphoepithelial lesions involving both a submandibular and then a parotid salivary gland. She eventually underwent pneumonectomy for lymphocytic interstitial pneumonitis with marked cystic degeneration and lung destruction. Although frank malignancy has not been demonstrated review of her nasopharyngeal biopsies and of her pulmonary pathology shows a tendency toward distinct cellular uniformity with loss of follicles and germinal centers. Concurrently, immunologic studies have demonstrated abnormalities of cell mediated (T cell) function.

Female↗
PubMed1988

Giant cementoblastoma simulating a peridental infection.

A case of giant cementoblastoma of the maxilla in a young female is reported. An unusual painful swelling of the gingivolabial area led to an initial misdiagnosis of a peridental infection and consequently to inappropriate treatment.

Adolescent↗
PubMed1988

Inclusion body myositis in post-poliomyelitis muscular atrophy.

A 38-year-old male developed a new muscle weakness in his left thigh 35 years after having acute paralytic poliomyelitis with residual right distal leg weakness and atrophy. EMG studies showed widespread denervation in proximal and distal muscles regardless the clinical involvement. Muscle biopsy from an affected muscle showed the findings of inclusion-body myositis consisting of perivascular and interstitial mononuclear infiltration, sarcoplasmic granular inclusions with membranous whorls and typical filamentous inclusions in several myonuclei. This raises the possibility of inclusion body myositis in other cases of progressive post-poliomyelitis muscular atrophy, especially those with perivascular infiltration of mononuclear cells in the muscle biopsy.

Adult↗
PubMed1985

Familial meconium ileus with normal sweat electrolytes.

Meconium ileus (MeI) is the presenting symptom in 10 to 15 percent of infants with cystic fibrosis (CF), but it is a rare phenomenon in patients who do not have this disease. We report four Bedouin siblings who had MeI with no laboratory evidence of CF.

Electrolytes↗
PubMed1984

Bilateral nasal glandular cysts: an occasional finding in rhinoplasty.

Clinical and pathological aspects of an unusual case of bilateral, multiple glandular cysts of the nasal mucosa, originating from both inferior turbinates, are herewith described, as an occasional finding in rhinoplasty. Although cystic structures are common in the upper respiratory tract, the development of a mucous cyst in the nasal cavity is a very rare occurrence. The differential diagnosis of nasal glandular cysts from other cystic conditions appearing in the nasal cavity is discussed.

Adult↗
PubMed1983

Trismus resulting from a parotid hemangioma.

A case of a hemangioma in a 56-year-old man is given. The hemangioma interfered with the anterior movement of the condyloid process and caused severe trismus. Removal of the tumor produced immediate relief of the trismus.

Hemangioma↗
PubMed1983

Thyroglossal duct remnant carcinoma.

Thyroglossal duct remnant carcinoma is a very rare malignancy arising from aberrant thyroid tissue. This diagnosis, however, should be considered in patients presenting with anterior neck masses. If there is no invasion of the capsule of the tumor, local excision with diligent follow-up is recommended as the treatment of choice.

Adenocarcinoma↗
PubMed1982

Aplasia cutis congenita in two sibs discordant for pyloric atresia.

We report two sibs who were the products of a consanguineous mating, and who had an extensive form of aplasia cutis congenita (ACC). In one of them the generalized skin disorder was manifested by slipping off of the epidermis and mucous membranes with the slightest trauma. This sib also had pyloric atresia and other congenital malformations. Two hypotheses are presented to explain the discordance between the siblings for the abnormalities other than the ACC. One hypothesis assumes varying degrees of severity of the same autosomal recessive disease. The second suggests linkage between the gene for ACC and the gene for an epidermolysis bullosa (EB)-like disorder and pyloric atresia. a recombination event involving the EB-pyloric atresia gene in one carrier parent would then lead to an offspring with only ACC. Prenatal diagnosis is suggested by monitoring alpha-fetoprotein levels in aminotic fluid.

Abnormalities, Multiple↗
PubMed1982

The biologic behavior of basal cell carcinoma: Part I.

The influence of histopathologic and clinical factors on the biologic behavior of basal cell carcinoma of the face is discussed on the basis of a retrospective study of 188 cases. Fourteen different parameters were studied and correlated with the histologic type and the frequency of incomplete excision of the lesions. The highest frequency of incompletely excised tumors was seen with the adenocystic and morphea types and with Clark level III lesions. The adenocystic type appeared to be the most aggressive form, with the highest frequency of thick lesions and the most marked mitotic activity. The histologic parameters studied provide more information about the behavior of basal cell carcinoma than the conventional subdivision into solid, morphea, and adenocystic types.

Adult↗