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Biomedical subjects

H van Ackeren

Publications and source records attributed to H van Ackeren.

11 recordsLinked to original sources

[Modern cancer therapy--an interdisciplinary task].

The diagnosis of cancer and the treatment of cancer patients are initially an interdisciplinary entity. Progress has been achieved through oncological multimodal cooperation between various forms of organisations. The ensuing problems confirm the following two main points. (1) The continuing delay in diagnosis of cancer still prevents most patients from benefitting from the implementation of optimal therapeutic possibilities and interdisciplinary cooperation. (2) What the surgeon does not achieve or neglects during the primary operation cannot be compensated for through conservative oncological measures.

Aftercare

Microvascular architecture of the mucosa of the gastric corpus in man.

Vascular casts of human gastric mucosa of the corpus area were studied by scanning electron microscopy and compared with vertical and horizontal series of semithin sections of perfusion-fixed corpus mucosa. The submucosal arteries give off short and long arterioles. The short arterioles branch into a basal capillary network reaching from the basis to the isthmus of the gastric glands. The long arterioles pass through the lamina propria without ramifications and supply a second, apical capillary layer reaching from the base to the top of the gastric pits. Anastomoses connect both capillary layers. Dense, convoluted capillaries at the mucosal surface encircle the gastric pits. Both capillary layers drain into venules at the level of the gastric pits. Below, on their way to the submucosal plexus, the venules do not receive any further capillary tributaries. In the examined tissue no arteriovenous anastomoses could be identified. A microvascular architecture with two capillary layers is presented, which guarantees a luxurious oxygenation throughout all layers of the gastric corpus mucosa in man. These findings are in contrast to previous descriptions of human corpus mucosa, where only one capillary layer, reaching from the base to the top of the corpus mucosa, has been identified.

Adult

[Principles of radical surgery of gastric carcinoma (author's transl)].

For over a decade, therapeutic results in cases of macrocarcinoma have remained almost constant. The absolute 5-year survival rate is 10-15%. However, in cases of early detection, the 5-year survival rate is over 90%. Systematic screening to detect the cancers early has resulted. The practical results is the systematic observation of high-risk groups. The therapy of choice for macrocarcinoma and cancer that is detected early is subtotal resection. Resection of the cardia should be replaced by gastrectomy, which should also be performed only when defined diagnostic criteria are met.

Gastrectomy