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Biomedical subjects

H van Ahlen

Publications and source records attributed to H van Ahlen.

At least 37 records · Page 2Linked to original sources

Neurophysiological investigations in potent and impotent men. Assessment of bulbocavernosus reflex latencies and somatosensory evoked potentials.

A multidisciplinary investigation was carried out on 130 patients with erectile dysfunction. The bulbocavernosus reflex (BCR) latency times were evaluated in all patients and in 116 the somatosensory evoked potentials (SSEP) were also assessed. BCR latency times were examined in 39 potent control patients and the SSEP were measured in 30 members of this group. There were no abnormal findings in the control group. Of the 130 patients with erectile dysfunction, 65 had anomalies in the BCR measurements and 36 of 116 patients had abnormal SSEP findings. When compared with the control group, 76 of 130 patients with erectile disorders (66%) had irregularities in BCR latency times and/or SSEP. As a result of these findings, lesions of the somatic penile innervation are considered to be one of the many causes of erectile dysfunction.

Adolescent↗

Antireflux procedure by Lich-Gregoir. Indications and results.

Reflux is not the cause of the ascension of microorganisms into the urinary bladder, yet it enables bacteria to reach the kidney and fosters pyelonephritis, persistent infections and nephropathy with all its consequences. The efficiency of the Lich-Gregoir antireflux procedure has to be judged by its results. The criterium of operative success in 190 renal units (146 children) is the positive influence on renal growth and physical development by controlling pyelonephritis and eliminating recurrent supravesical infections in more than 98% of the operated children.

Child↗

Pediatric blunt renal trauma--surgical or conservative treatment?

To evaluate the indications for conservative and surgical treatment, we analyzed the type of injury, associated injuries, diagnostic procedures and the results of therapy. Contusions were treated conservatively. In the 24 severe injuries surgery rate was 66% (16/24), renal loss rate was 16% (4/24), the other organs being saved by the operation. With primarily conservative treatment we had to operate in 1 case only due to recurrent hematuria; the renal loss rate was 0%. As indications for surgical treatment we defined: (1) deteriorating vital signs, (2) pedicle injuries and (3) large extravasations of contrast medium.

Adolescent↗

[Inguinal metastasis of stage I testicular tumors].

In 9 of 152 patients treated between 1975 and 1985 for stage I germ cell tumours of the testis we saw inguinal metastases. They appeared 2 to 26 months (median = 9.3 months) after orchiectomy and unilateral lymphadenectomy, including peri-iliac lymphadenectomy. In 3 cases predisposing factors such as surgical interference or local tumour extent explained the unusual metastasis; in 6 patients it was obviously due to atypical lymphatic drainage. The therapy of choice in these cases is (adjuvant) chemotherapy and salvage lymphadenectomy in the case of residual tumour.

Antineoplastic Agents↗

[Current views of prune belly syndrome].

The recent literature is reviewed and the etiology, pathogenesis, diagnosis, therapy and prognosis of prune belly syndrome are presented and illustrated with reference to personal experience in typical cases. It seem possible that the syndrome is not an entity in its own right, since it also appears in incomplete forms. Prenatal sonography allows an early diagnosis, but to date intrauterine treatment is not indicated. Postnatal operative intervention in the form of major reconstructive surgery has to be viewed very critically. So far, no positive effects on long-term prognosis have been proven, so that, depending upon the severity of the syndrome, treatment should be as conservative as possible.

Abdominal Muscles↗

[Comparison of papaverine-induced Doppler sonography and angiography in the diagnosis of erectile dysfunction].

In the course of the evaluation of 500 patients with erectile dysfunction the results of penile Doppler-sonography and penile angiography could be compared in 65 patients, in whom both investigations were carried out under standardized conditions. Criteria for the evaluation of penile Doppler-sonography were the wave form analysis and especially the increase of blood-flow in the investigated arteries after intracavernous injection of papaverine. Criteria for the evaluation of the angiograms were the depiction of the penile arteries as well as the evidence of obstruction and collaterals of the internal iliac and pudendal arteries. In regard to the dorsal penile artery an all over correlation of 96.1% and in regard to the deep penile artery of 92.3% could be found. Based on these findings the conclusion can be drawn that papaverine-induced Doppler-sonography is able to replace penile angiography, thus no longer serving as the golden standard in the diagnosis of arterial insufficiency.

Angiography↗

[Ectopic ureterocele--diagnosis and therapy].

The ectopic ureterocele is a relatively frequent congenital abnormality of the urinary tract. Its clinical signs are often uncharacteristic. Therefore the sometimes discrete changes in the diagnostic evaluations have to be looked for. The various procedures of which the excretory urography still plays a central role are discussed with their possibilities and limitations. The removal of the mostly dysplastic upper segment with its ureter is usually the most sensible treatment. Only in rare cases, where scintigraphically and clinically the segment seems preservable, a ureteropyelostomy is indicated. The different indications for primary and secondary excision of the ureterocele itself are outlined. A minimal therapy, that does not correct the underlying anatomical abnormality like the endoscopic incision should be reserved for uroseptic emergencies.

Child↗

Relevance of dynamic cavernosography to the diagnosis of venous incompetence in erectile dysfunction.

Dynamic cavernosography with flow and cavernosometric studies was performed on 140 patients, 18 of whom served as a control group. Of the 122 multidisciplinary investigated patients with erectile dysfunction 66 (54.1 per cent) showed associated venous leakage. Insufficiency of the dorsal penile veins (29 patients, 44 per cent) and complicated venous leakage (23 patients, 34.8 per cent) were predominate. In 63 patients with erectile dysfunction the results of an additional papaverine test were compared to the results of dynamic cavernosography, and they indicated a sensitivity of more than 90 per cent in regard to evidence or exclusion of venous incompetence in erectile dysfunction.

Adult↗

[Blunt kidney trauma in childhood].

In a retrospective analysis of 42 paediatric blunt renal injuries the indications for conservative and surgical treatment were evaluated. The type of injury (contusion, laceration, fragmentation, pedicle injury), associated injuries, the diagnostic procedures, the therapy and its results were analysed. All 18 contusions were treated conservatively. For the 24 severe injuries there was a surgery rate of 66% (16/24), a renal loss rate of 16% (4/24); the other organs could be saved by the operation. With primarily conservative treatment we had to operate in one case only due to recurrent haematuria; the renal loss rate was 0%. The following criteria are defined as indications for surgical treatment: (1) deteriorating vital signs, (2) pedicle injury, (3) large devitalized renal segments, (4) large extravasations of contrast medium ("Page kidney").

Adolescent↗

[Etiology and therapeutic possibilities of post-traumatic erectile impotence].

Based on 12 patients with posttraumatic erectile dysfunction due to pelvic fractures, ruptures of urethra and straddle-trauma, the diagnostic and therapeutic means in the management of erectile failure are discussed. The most frequent etiology encountered in posttraumatic erectile failure were combined arterial-neurogenic lesions followed by insufficiencies of the venae profundae penis as a sequelae of pelvic fractures or symphyseal ruptures. Promising therapeutic alternatives represent injections of cavernous bodies with vasoactive drugs, penile implants and also in suitable cases penile revascularization procedures.

Adult↗

[Dynamic cavernosonography and intracavernous drug testing in the diagnosis of erectile dysfunction].

Based on 216 dynamic cavernosographies, performed in 25 patients with normal erectile capacity and in 191 patients with erectile dysfunction, an evaluation of this method in regard to its diagnostic validity in erectile dysfunction was possible. An additional comparison of the results of intracavernous application of vasoactive drugs with the outcome of dynamic cavernosography in 141 patients showed that a negative or clearly positive test-outcome indicated in over 90 per cent of the evaluated patients the presence or lack of venous insufficiency during dynamic cavernosography.

Adolescent↗

[Current diagnosis of pediatric kidney trauma: consequences for therapy planning].

For the therapy of pediatric renal trauma there is always the question of the appropriate diagnostic measures. The various procedures such as ultrasound, urography, scintigraphy, computed tomography, conventional angiography, arterial and venous digitalized subtraction angiography are discussed. By these new methods it is possible to judge the severity of renal trauma more accurately and to limit the indications for an operation. With stable circulation an operation should only be performed in the presence of a large, expanding retroperitoneal hematoma, extensive extravasation (urinoma), persistent massive hematuria or if large areas of devitalized renal tissue are found.

Adolescent↗

[Hemangioma of the kidney--diagnostic and therapeutic problems].

Hemangioma of the kidney as one of the possible causes of "essential hematuria" is discussed with special regard to its diagnostic features in the various modern radiological examinations. Still most important is angiography. Typical findings are demonstrated in a case with complete replacement of the parapelvic fat by a large cavernous hemangioma. The various therapeutic possibilities--conservative treatment, embolisation, partial or complete nephrectomy - are discussed.

Adult↗

[Dynamic cavernosography. Radiologic diagnosis of venous induced erection disorders and erectile body diseases].

In 30 to 50% erectile dysfunctions are due to vascular disorders. Roughly a third of these vasculogenic disturbances is based on venous disorders. These venous-induced erectile failures may be objectivated and radiologically located via dynamic cavernosography, combined with a simultaneous recording of a cavernous pressure profile. Based on over 130 examinations it was possible to provide both an exact description of the normal venous drainage in normal potent men and to give a good idea of the different venous leakages in patients complaining of erectile dysfunctions. Congenital and acquired penile deviations along with Peyronie's disease may also be appropriate for dynamic cavernosography.

Adolescent↗