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Biomedical subjects

H van Calker

Publications and source records attributed to H van Calker.

15 recordsLinked to original sources
PubMed1991

[Atypical thyroid gland adenoma. Experiences during 12 years struma surgery].

In a period of 12 years atypical adenomas were found in 82 cases and thyroid carcinomas were diagnosed in 93 patients in the main group of 2176 patients undergoing a thyroid resection. Mean age was 46.5 years for atypical adenomas and 48 years for carcinomas. In 76.8% of the cases with atypical adenomas the postoperative course and long term results were followed up. None of these patients developed a recurrence or malignancy. 93.3% of the patients were treated with Levothyroxin for prevention. Hyperthyroidism did not occur pre- or postoperatively.

Adenoma↗
PubMed1987

[Problems of pelvic infection following rectopexy using synthetics and its treatment].

The complication of the infected Ivalon-sponge after rectopexy is described in five patients. In two patients the pelvic sepsis perforated spontaneously into the vagina and in another two patients the pelvic abscess perforated through the levator muscles into the ischio-rectal fossa formating a typical horse-shoe abscess in one case. The management of choice in cases of pelvic sepsis is the complete removal of the infected Ivalon-sponge. We personally prefer the laparotomy for the complete removal of the prosthesis and not the removal through the vagina or through the rectum.

Abscess↗
PubMed1985

[Current aspects of the surgical treatment of colonic ileus caused by stenosing colonic carcinoma].

Formerly it was considered dangerous to undertake resection in the presence of colonic obstruction. This idea has been abandoned. Immediate right hemicolectomy is the accepted treatment for obstructed lesions of the right colon. For obstruction of the left colon proximal colostomy or caecostomy are being challenged by immediate resection as a Hartmann operation with iliac colostomy or finished with a colo-colonic or colo-rectal anastomosis. A subtotal colectomy with ileo-sigmoid or ileo-rectal anastomosis is a further method with encouraging experiences. From 1979-1984 a series of 33 patients with obstruction from a carcinoma of the left colon underwent emergency abdominal colectomy with primary ileosigmoidostomy or ileorectostomy without diversion. The mortality and morbidity was favourable compared with those reported in series of similar cases treated by stages procedures or primary resection. Several advantages of this method are explained and further encouraging experiences from other centers are reported.

Adenocarcinoma↗
PubMed1983

[Use of Dukes' classification in rectal cancer].

An account is given of the historical development of various modifications of the Dukes classification. These modifications are rather different from the original classification. In some modifications the muscularis propria is falsely identified as muscularis mucosae. Therefore the term "modified Dukes classification" should be omitted, and should be replaced by a classification bearing the name of the respective author.

Humans↗
PubMed1983

[Emergency colectomy using primary anastomosis in obstructive cancer of the left colon].

From 1979-1982 a small series of 12 patients with obstruction from a carcinoma of the left colon underwent emergency abdominal colectomy with primary ileosigmoidostomy or ileorectostomy without diversion. The mortality and morbidity was favourable compared with those reported in series of similar cases treated by staged procedures or primary resection. This study could not document the more advanced state of cancers with acute obstruction. Further follow-up of this series is needed. This procedure is conceptually attractive in cases with obstructing left side carcinomas.

Aged↗
PubMed1983

[Does an obturation in colorectal cancer also modify the behavior of the serum CEA level?].

The CEA-plasma level was determined in 10 patients with malignant obstruction of the large intestine and in 6 patients with benign obstruction of the small intestine. The plasma carcinoembryonic antigen levels were obtained prior to initiating of the treatment and sequentially after treating the complete obstruction. Elevated plasma carcinoembryonic antigen levels are related to the carcinoembryonic antigen production by the primary tumour and not additionally to the obstruction. An elevated plasma CEA level in patients with benign obstruction could not be detected. After relief of obstruction, significant changes in the mean carcinoembryonic antigen values could not be observed.

Adenocarcinoma↗
PubMed1982

[Leiomyoblastoma of the stomach (author's transl)].

Clinical symptomatology, pathology and surgical management of five patients with gastric leiomyoblastoma are reported. Leiomyoblastomas of the gastrointestinal tract are defined as a group of tumors, which originate from the smooth muscle, and which have to be classified in between benign leiomyomas and malignant leiomyosarcomas. These tumors metastasize in about 10% of cases. Patients come to the hospital in most cases because of unspecific upper abdominal symptoms. During surgery one usually finds solitary, well defined, cystic tumors of a size of 0.5 to 30 cm expanding intramurally versus neighbouring structures; ulcerations of the gastric mucosa are rare. The diagnosis is established by microscopic examination during surgery. Treatment is extensive excision of the tumor.

Adult↗
PubMed1980

[Congenital tuberculosis (author's transl)].

A prematurely born infant (35 weeks of gestational age) developed signs of respiratory insufficiency, and fever, beginning at the 17th day of life; x-ray examinations showed small and large spotted lung infiltrations which grew and confluated rapidly in spite of broad antibiotic treatment. At the 29th day intubation and artificial ventilation became necessary; cultures of tracheal fluid remained sterile, Ziehl-Neelsen stains were not done. The infant died at the age of 35 days. Only at autopsy the diagnosis " congenital tuberculosis" could be made; examinations of the mother who was thought to be healthy, revealed a severe epitheloid cell tuberculosis of the endometrium. -- Mode of transmission, pathology, clinical symptoms, prophylaxis, and therapy of congenital tuberculosis are being reviewed.

Endometritis↗
PubMed1980

[Local recurrence following anterior resection of rectal cancer. CEA-titer (author's transl)].

The records of 70 patients undergoing a curative anterior resection at the Surgical Department of the Academic Teaching Hospital in Herford for carcinoma of the rectum between January 1, 1974 and December 31, 1978 were reviewed. There were 6 cases (8,5%) developing suture line and local recurrence between 9 and 16.5 months after anterior resection. In this study a rising CEA-titer was the first evidence of recurrence in only 29% of our patients. Among 9 patients with confirmed local recurrence - 6 from our own and 3 from outside - only 2 (22%) showed an increase in CEA levels above normal. In the face of the poor 5-year survival with secondary abdomino-perineal resection following anterior resection one must ask if the significance of those operative procedures with their technical difficulty is justified. Our own experience of 9 patients with secondary abdominoperineal resection for local recurrence has changed our mind for a more palliative operative procedure in such cases.

Carcinoembryonic Antigen↗
PubMedDate not supplied

A retrospective study of serial CEA determinations in the early detection of recurrent colorectal cancer.

In the past five years, routine CEA determinations have been carried out on all patients after curative operation for colorectal carcinoma. These patients also underwent a clinical follow-up examination in the Oncology Outpatient Department. In 86 patients, recurrence of a tumor was confirmed. In 31 cases, a second-look operation was carried out. The CEA determinations were retrospectively analyzed in these patients and correlated with the time the recurrence of the tumor was diagnosed. These results show that of 86 patients only 15 (17.4 per cent) had pathologic CEA values before clinical symptoms of tumor recurrence. In the patient group with local recurrence, only 11 (23.9 per cent) of 46 patients had previously pathologically raised CEA values. Of 31 patients, 15 (48.4 per cent) underwent curative resection after the second-look operation. At this time, 12 patients (38.7 per cnt) still had normal CEA values, whereas only three patients (9.7 per cent) had pathologically raised CEA values. From these results, it was established that early diagnosis of tumor recurrence was very low. Therefore, one should not rely more on postoperative routine CEA determinations in the postoperative monitoring of patients following curative operations for colorectal carcinoma than on regular comprehensive follow-up examinations of these patients.

Carcinoembryonic Antigen↗