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Biomedical subjects

H van Doorne

Publications and source records attributed to H van Doorne.

5 recordsLinked to original sources

Microbial contamination of a vitamin A formulation, prepared in local pharmacies, and its preservation against yeasts and moulds.

The microbial contamination of 44 samples of a vitamin A preparation in sucrose syrup was investigated. The contaminants were almost exclusively yeasts and moulds. Microbiological and physicochemical studies showed that sorbic acid was the preservative of choice for this formulation. The results are discussed with respect to the preservation of non-sterile pharmaceuticals.

Drug Contamination

Liquid modification of Baird-Parker's medium for selective enrichment of Staphylococcus aureus.

A liquid modification of Baird-Parker's medium is suggested for the detection of low (less than 20/g) numbers of Staphylococcus aureus. Model experiments showed that the medium had an acceptable level of selectivity and that it was non-inhibitory to injured cells. Practical evaluation demonstrated the advantage of selective enrichment procedures over both non-selective enrichment technique and direct plating methods.

Bacteriological Techniques