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Biomedical subjects

Hajime Harauchi

Publications and source records attributed to Hajime Harauchi.

7 recordsLinked to original sources

Microcatheter tip enhancement in fluoroscopy: a comparison of techniques.

We compared three techniques for enhancement of microcatheter tips in fluoroscopic images: conventional subtraction technique (CST); averaged image subtraction technique (AIST), which we have developed; and double average filtering (DAF) technique, which uses nonlinear background estimates. A pulsed fluoroscopic image sequence was obtained as a microcatheter was passed through a carotid phantom that was on top of a head phantom. The carotid phantom was a silicone cylinder containing a simulated vessel with the shape and curvatures of the internal carotid artery. The three techniques were applied to the images of the sequence, then the catheter tip was manually identified in each image, and 100 x 100 pixel images, centered at the indicated microcatheter tip positions, were extracted for the evaluations. The signal-to-noise ratio (SNR) was calculated in each of the extracted images from which the mean value of the SNR and its standard deviation (SD) were calculated for each technique. The mean values and the standard deviations were 4.36 (SD 3.40) for CST, 6.34 (SD 3.62) for AIST, and 3.55 (SD 1.27) for DAF. AIST had a higher SNR compared to CST in almost all frames. Although DAF yielded the smallest mean SNR value, it yielded the best SNR in those frames in which the microcatheter tip did not move between frames. We conclude that AIST provides the best SNR for a moving microcatheter tip and that DAF is optimal for a temporarily stationary microcatheter tip.

Carotid Artery, Internal↗

Tracking technique of a micro guide wire in sequential fluorograms.

In this paper, we propose a tracking technique for a micro guide wire in a sequence of fluorograms. A technique in which the region-growing technique was embedded was developed. It gives the center line of a micro guide wire. A sequence of 1,024 x 1,024 x 16 bit fluorograms (111 frames) with a carotid phantom and head phantom was obtained with a CAS-8000V (Toshiba America Medical Systems, Inc., CA, USA) C-arm angiography system and a Hi-Torque Standard micro guide wire (Advanced Cardiovascular Systems, Inc., CA, USA). To evaluate the technique, we manually traced the guide wire in each sequence frame three times, and a "true" single-width micro guide wire was created from them. The number of pixels on the true guide wire and inside the two-pixel tolerance of the center line was counted in each fluorogram, and the percentage of that count based on the number of all pixels on the true guide wire was calculated as true positive (TP). In addition, the number of pixels on the center line and outside the two-pixel tolerance of the true guide wire was counted in each frame as false positive (FP). The tracking technique has a mean TP of 94.8% and a mean FP of 5.1 pixels/frame. Several frames have low TP and high FP, but the technique could continue to track the micro guide wire until the end of the sequence. We therefore concluded that we had developed an accurate automatic tracking technique for micro guide wires in fluoroscopic sequences.

Algorithms↗

An inductive method for automatic generation of referring physician prefetch rules for PACS.

To prefetch images in a hospital-wide picture archiving and communication system (PACS), a rule must be devised to permit accurate selection of examinations in which a patient's images are stored. We developed an inductive method to compose prefetch rules from practical data which were obtained in a hospital using a decision tree algorithm. Our methods were evaluated on data acquired in Osaka University Hospital for one month. The data collected consisted of 58,617 cases of consultation reservations, 643,797 examination histories of patients, and 323,993 records of image requests in PACS. Four parameters indicating whether the images of the patient were requested or not for each consultation reservation were derived from the database. As a result, the successful selection sensitivity for consultations in which images were requested was approximately 0.8, and the specificity for excluding consultations accurately where images were not requested was approximately 0.7.

Algorithms↗

Development of a system which automatically acquires optimal discrete-valued attributes by dividing and grouping continuous-valued attributes to assist clinical decision making in radiotherapy.

The purposes of this study were first to develop a system which statistically tests results of radiotherapy and which automatically acquires an optimal discrete-valued attribute by dividing and grouping continuous-valued attributes, and second to find the optimal range of values such as tumor dose by taking account of the conditions and statistics in ROGAD (Radiation Oncology Greater Area Database), a multi-institutional database in Japan. Our ultimate goal is to assist clinical decision making for every patient. In this research, two algorithms for acquiring a boundary value were developed without detecting false boundaries or accidental errors of acquired boundaries. The resolution of detected discrete-valued attributes and speed of convergence were confirmed to be practical. The optimal range of given tumor dose with the best reaction and with the fewest complications is expected to be clarified.

Algorithms↗

Evaluation of the effect of varying MPEG-2 compression ratios on digital coronary angiographic assessment of stenosis severity.

The purpose of this study is to evaluate the influence of MPEG-2 compression scheme on coronary angiography and to search the highest compression ratio at which no significant effect to accuracy of assessment of stenosis severity occurs. Forty-Four digital cine angiographies were used. Three cardiologists participated in a subjective study in which they read both uncompressed images and compressed images. Furthermore, an objective study was carried out to measure vessel stenosis ratio by using software. The influence of compression was evaluated by kappa statistics in case of subjective study and by both systematic error and random error in case of objective study. Kappa statistics between uncompressed image and compressed image at a ratio of 80:1 was significantly lower than that of other compression ratios such as 40:1. Similar results were obtained in objective evaluation. In this report, the authors provide the baseline for further studies on observer performance for motion images.

Coronary Angiography↗

Methodology development for quantitative optimization of security enhancement in medical information systems -Case study in a PACS and a multi-institutional radiotherapy database-.

The target of our study is to establish the methodology for analyzing level of security requirements, for searching suitable security measures and for optimizing security distribution to every portion of medical practice. Quantitative expression must be introduced to our study as possible for the purpose of easy follow up of security procedures and easy evaluation of security outcomes or results. Results of system analysis by fault tree analysis (FTA) clarified that subdivided system elements in detail contribute to much more accurate analysis. Such subdivided composition factors very much depended on behavior of staff, interactive terminal devices, kinds of service, and routes of network. As conclusion, we found the methods to analyze levels of security requirements for each medical information systems employing FTA, basic events for each composition factor and combination of basic events. Methods for searching suitable security measures were found. Namely risk factors for each basic event, number of elements for each composition factor and candidates of security measure elements were found. Method to optimize the security measures for each medical information system was proposed. Namely optimum distribution of risk factors in terms of basic events were figured out, and comparison of them between each medical information systems became possible.

Computer Security↗

Development of a Virtual Private Database for a multi-institutional Internet-based Radiation Oncology Database overcoming differences in protocols.

A multi-institutional Radiation Oncology Greater Area Database (ROGAD) was started in 1991 under the direction of the Japanese Society for Therapeutic Radiology and Oncology (JASTRO). Use of ROGAD was intended to allow reflection of results of data analysis into treatment strategy and treatment planning for individual cases, to provide quality assurance, to maximize the efficacy of radiotherapy, to allow assessment of new technologies or new modalities, and to optimize medical decision making. ROGAD collected 13,448 radiotherapy treatment cases from 325 facilities during the period from 1992 to 2001. In 2000, questionnaires were sent to 725 radiotherapy facilities throughout Japan, to further obtain the situation of the radiation oncology database. Workers at 179 facilities replied that"the protocol of my facility is different from ROGAD protocol and I must send data according to the ROGAD protocol". So, we developed the Virtual Private Database System (VPDS) which is operated as if an oncologist had a database solely owned by his own facility, in spite of actually operating ROGAD. VPDS realizes integration of different plural databases, regardless of differences in entry methods, protocols, definitions and interpretations of contents of clinical data elements between facilities.

Clinical Protocols↗