Biomedical subjects

Hal Smith

Publications and source records attributed to Hal Smith.

4 recordsLinked to original sources

PubMed2003

The Freter model: a simple model of biofilm formation.

A simple, conceptual model of biofilm formation, due to R. Freter et al. (1983), is studied analytically and numerically in both CSTR and PFR. Two steady state regimes are identified, namely, the complete washout of the microbes from the reactor and the successful colonization of both the wall and bulk fluid. One of these is stable for any particular set of parameter values and sharp and explicit conditions are given for the stability of each. The effects of adding an anti-microbial agent to the CSTR are examined.

Algorithms↗

PubMed2003

Feedback control for chemostat models.

It is shown that a chemostat with two organisms can be made coexistent by means of feedback control of the dilution rate. Remaining freedom in the feedback law can be used to guarantee robustness or improve particular performance indices. Unfortunately a topological property prevents coexistence by feedback control for chemostats with more than two organisms. We apply our results to control bioreactors aimed at producing commercial products through genetically altered organisms. In all our results the coexistence takes its simplest form: a global asymptotically stable equilibrium point in the interior of the non-negative orthant.

Bacteria↗

PubMed2002

Central New York Psychiatric Center: an approach to the treatment of co-occurring disorders in the New York State correctional mental health system.

Central New York Psychiatric Center operates a maximum security inpatient treatment hospital and outpatient mental health services for all of the 72 New York State prisons. In this article prevalence data, patient characteristics, and interventions offered to inmates diagnosed with co-occurring mental illness and substance abuse disorders in the New York State prison system are reviewed and discussed. Available interventions have resulted from the close collaboration of the State Department of Correctional Services and State Office of Mental Health. Aspects of current programs and plans for future service developments are discussed along with implications for the treatment of an offender population diagnosed with a co-occurring disorder.

Adult↗

PubMed2002

Personality disorders in prison: aren't they all antisocial?

The provision of mental health services in the correctional system is challenging at best for various clinical, administrative, and structural reasons. Among the complicating factors is the assessment and management of character pathology which either confounds the treatment of more "serious" mental illnesses, e.g. Axis I disorders, and/or presents itself as the primary focus for intervention. In this paper we review the prevalence of personality disorders on the prison mental health services caseload in New York State. We compare inpatient and out-patient rates among the various disorders documented in the prison system, as well as look at these rates within the context of the rates of personality disorder in the state mental health system generally. Assessment of personality disorder will be addressed with particular attention to the confounding influence of the prison environment. Finally, treatment options will be discussed, including discussion of new initiatives that attempt to address inmates with serious mental illness and personality traits that lead to disciplinary housing.

Adult↗