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Biomedical subjects

Hans-Peter Haring

Publications and source records attributed to Hans-Peter Haring.

6 recordsLinked to original sources
PubMed2005

Thrombolysis beyond the guidelines: two treatments in one subject within 90 hours based on a modified magnetic resonance imaging brain clock concept.

BACKGROUND AND PURPOSE: We report the first case of 2 intravenous thrombolysis treatments within 90 hours in a patient with early recurrent stroke. SUMMARY OF REVIEW: A 50-year-old man had improved significantly after intravenous thrombolysis for acute stroke. On the fourth day, he deteriorated dramatically because of recurrent stroke. Evidence of vessel reocclusion and profound perfusion/diffusion mismatch constituted the rationale for a second thrombolysis treatment, which resulted in vessel recanalization and significant neurologic improvement. CONCLUSIONS: The pathophysiological information obtained by multimodal magnetic resonance imaging may suit as a brain clock when repeat thrombolysis treatment is considered for early recurrent stroke.

Brain↗
PubMed2005

[When is a clinical study non-commercial?].

A non-commercial study is a research project not aiming at the protection of a commercial institution's interests. The classification of a clinical study as non-commercial or commercial makes sense and is important especially for clinical research teams, ethics committees and hospital owners because of relevant differences in the image and cost fields. The support of non-commercial studies by commercial institutions like pharmaceutical companies is permissible, unless it is tied to conditions impairing impartiality in respect of design, publication of study results or ownership of the assessed data. Specific relationships between the investigator and a company of the health industry potentially profiting from the study results (e.g. major share holdings or financial dependences) favour the classification of a study as commercial. The reliable classification of a study as non-commercial is only possible if all aids and grants, all conflicts of interest and special agreements are disclosed.

Austria↗
PubMed2002

Cognitive impairment after stroke.

The concept of vascular dementia is undergoing revision. The multi-infarct model and the Alzheimer's model of dementia, usually referred to as 'multi-infarct dementia', are gradually being replaced by a much broader concept of vascular cognitive impairment. This conceptual evolution reflects a more profound understanding of the pathogenic mechanisms that underlie this complex syndrome. As a consequence of this revision new diagnostic criteria have been established during the past 25 years, resulting in new problems with regard to precise disease definition and limited inter-rater reliability. The particular criteria chosen by a clinician or investigator to diagnose vascular dementia have a major impact on epidemiology, disease management and health economic estimates.

Cognition Disorders↗