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Harald O Heymann

Publications and source records attributed to Harald O Heymann.

16 recordsLinked to original sources

Use of hydrogen peroxide-based tooth whitening products and its relationship to oral cancer.

UNLABELLED: Tooth whitening products containing hydrogen peroxide or carbamide peroxide were evaluated in this review for potential oral cancer risk from their use. Hydrogen peroxide is genotoxic in vitro, but not in vivo. Hydrogen peroxide was not considered to pose a genotoxic risk to humans. The animal toxicology data relevant to the assessment of the carcinogenicity of hydrogen peroxide do not indicate that it has significant carcinogenic activity at any site, including the oral cavity. Hydrogen peroxide was found to enhance the carcinogenic effects of potent DNA reactive carcinogens in experimental animals. However, these experimental conditions are artificial as they are related to high exposures and are of no relevance to potential human exposures to low quantities of hydrogen peroxide from the use of tooth whitening products. Clinical data on hydrogen peroxide-containing tooth whitening products show no evidence for the development of preneoplastic or neoplastic oral lesions. Exposures to hydrogen peroxide received by the oral cavity are exceedingly low, of short duration (30-60 minutes), and could not plausibly enhance any carcinogenic risk associated with exposure of the oral cavity to chemicals in cigarette smoke or to alcohol, both known risk factors for the development of oral cancer. CLINICAL SIGNIFICANCE: Based on a comprehensive review of the available literature and research, the use of tooth whitening products containing hydrogen peroxide or carbamide peroxide does not appear to pose an increased risk of oral cancer in the general population, including those persons who are alcohol abusers and/or heavy cigarette smokers.

Journal Article↗

The Carolina bridge: a novel interim all-porcelain bonded prosthesis.

UNLABELLED: Numerous bonded bridge designs have been advocated over the years for the temporary or permanent replacement of missing teeth. Both metal and all-porcelain designs of bonded bridges have been advocated, with varying degrees of success. However, all of these designs involve some degree of tooth preparation, making them irreversible in nature. The Carolina bridge, a novel all-porcelain bonded pontic, requires no significant tooth preparation, making it an outstanding option as an interim prosthesis. The key to success is the availability of adequate surface area interproximally to ensure optimally strong resin composite connectors. CLINICAL SIGNIFICANCE: This article describes the indications, contraindications, and clinical technique for the placement of an ultraconservative all-porcelain bonded bridge for the interim replacement of single incisors.

Composite Resins↗

Effect of whitening dentifrices on the superficial roughness of esthetic restorative materials.

PURPOSE: The purpose of this study was to investigate the surface roughness (Ra) of different esthetic restorative materials following simulated toothbrushing using different whitening dentifrices. MATERIALS AND METHODS: Cylinders of Esthet-X (Dentsply Caulk, Milford, DE, USA), Durafil VS (Heraeus Kulzer, Wehrheim, Germany), and Vitremer (3M ESPE, St. Paul, MN, USA) were made using molds (4 mm in diameter for 2 mm in height). The superficial roughness was evaluated using a profilometer (Ra) with a cutoff length of 0.25 mm and a speed of 0.1 mm/s. The specimens (N=13) were submitted to 7,500 brushing cycles using five different toothpastes: (1) Crest Regular (control; Procter & Gamble): silica abrasive (C); (2) Crest Extra Whitening (Procter & Gamble, Cincinnati, OH, USA): bicarbonate+calcium pyrophosphate (CE); (3) Dental Care A & H (Arm & Hammer, Camilla, GA, USA): bicarbonate (DC); (4) Rembrandt Plus Whitening (Oral B Laboratories, Belmont, CA, USA): carbamide peroxide+alumina/silica (RP); and (5) experimental: hydrogen peroxide+calcium carbonate (EX). RESULTS: The data were analyzed by analysis of variance and Tukey's test (alpha=.05) for each restorative material, and the results [difference between final and initial roughness: Ra(F)-Ra(I) in microm] were as follows: Esthet-X: EX=0.15+0.07a; RP=0.29+0.16a; CE=0.96+0.33b; C=1.03+0.29b; DC=1.48+0.37b; Durafil VS: RP=0.09+0.07a; EX=0.55+0.23abc; C=0.96+0.26bc; CE=1.03+0.33cd; DC=1.09+0.37d; and Vitremer: EX=0.10+0.08a; RP=0.26+0.19a; CE=0.94+0.27b; DC=1.13+0.46bc; C=1.50+0.32c (different letters mean differences among groups). CONCLUSION: It was verified that the dentifrices containing carbamide or hydrogen peroxide along with alumina+silica and calcium carbonate, respectively (groups 4 and 5), produced minor changes in Ra when compared with the control group and with those dentifrices containing bicarbonate (groups 2 and 3). CLINICAL significance The results of this study indicate that whitening dentifrices evaluated containing silica or calcium carbonate were less abrasive when used on the resin-based esthetic restorative materials than those that contain sodium bicarbonate.

Aluminum Oxide↗

Microhardness evaluation of in situ vital bleaching on human dental enamel using a novel study design.

OBJECTIVES: The aim of this 'in situ' study was to evaluate the microhardness of dental enamel following treatment with an in-office and an at-home vital bleaching agent through a novel approach using samples temporarily bonded 'in vivo'. METHODS: Human dental enamel slabs (n=88) were subjected to sequential polishing and initial Knoop microhardness tests were performed. The slabs were fixed to the facial surfaces of the maxillary first molars of 44 human volunteers. They were divided into four groups (n=11) according to the treatment group: G1- in-office-CP37+ at-home-CP10; G2- in-office-CP37+ at-home-PLA; G3- in-office-PLA and at-home-CP10; G4- in-office and at-home-PLA. After 3 weeks of treatment, final microhardness measurements were performed. RESULTS AND SIGNIFICANCE: ANOVA and Tukey's HSD hoc analysis (alpha=0.05) revealed no differences among initial or final microhardness values (p>0.05); however, significant differences occurred between initial and final values for each group (p<0.01), The evaluation of microhardness revealed a reduction of 6.8% for G1, 4.1% for G2, 3.4% for G3 and 3.5% for G4. In-office bleaching with 37% carbamide peroxide, an at-home bleaching with 10% carbamide peroxide, and a combination of both resulted in lower enamel microhardness when measured immediately post-treatment. However, long-term effects of these treatments are not known, and are believed to be clinically insignificant due to the relatively small reductions observed in enamel microhardness. Interestingly, the carrier, Cabopol 934P, also resulted in similar reduction in enamel microhardness even when administrated alone as a placebo.

Acrylates↗

Effects of saliva contamination on resin-resin bond strength.

OBJECTIVE: The purpose of this study is to evaluate the effects of saliva contamination on microtensile bond strength (microTBS) between resin interfaces and to determine which decontamination methods best re-established the original resin-resin bond strength. MATERIALS AND METHODS: Ninety-six light-cured resin composite cylinders of Z-250, Renew, Clearfil APX, and Pertac II were randomly divided into six groups. For each material, one group of specimens was not contaminated, serving as the control. For the other specimens, the top surface of each block was treated with saliva that was slowly dried (Treatment 1); dried forcefully (Treatment 2); slowly dried, rinsed, and dried (Treatment 3); slowly dried, rinsed, dried, and bonded with Single Bond, One-Step, Clearfil SE Bond, or Prompt L-Pop (Treatment 4); or slowly dried, but not rinsed, and bonded using the same adhesives (Treatment 5). Two 2-mm increments of resin composite were applied and light-cured. After 24 h, the assemblies were trimmed for microtensile bond testing and were loaded to failure at 1 mm/min. Data were analyzed using two-way and one-way ANOVA and Fisher's PLSD (p<0.05). RESULTS: Control values ranged from 45.1 MPa for Pertac II to 71.5 MPa for APX. Treatment 1 caused significant reduction in resin-resin bond strength for all materials tested but for two of the materials in treatment 2. Pertac II was the only material that did not show a statistical difference from control group for treatment 3. Treatment 4 re-established the control values for Z-250 and Renew and treatment 5 was the only one to show no statistical difference for all materials tested. SEM observation revealed a smooth surface in treatment 1, but treatment 3 showed a few craters. Treatment 4 and 5 showed a mixture of cohesive failure in the composite and adhesive. SIGNIFICANCE: The most reliable method for decontaminating saliva from resin surfaces involves the application of adhesives.

Adhesiveness↗

Effects of blood contamination on resin-resin bond strength.

OBJECTIVE: Incremental placement and curing of resin composites has been recommended. However, this requires longer operating time, and therefore, increased risk of contamination. The purpose of this study was to evaluate the effects of blood contamination on microtensile bond strengths (microTBS) between resin interfaces and to determine the best decontamination method to re-establish the original resin-resin bond strength. MATERIALS: The top surfaces of 64, 4-mm composite blocks (Z-250, Renew, APX, Pertac II) were untreated as the control, or were treated as follows: blood applied and dried on the surface (Treatment 1), blood applied, rinsed, dried (Treatment 2), blood applied, rinsed, and an adhesive applied (Single Bond, One-Step, Clearfil SE, Prompt L-Pop) (Treatment 3). Fresh composite was applied and light-cured in 2-mm increments. After 24 h storage in water, the specimens were sectioned into 0.7-mm thick slabs, trimmed to a cross-sectional area of 1 mm(2), and loaded to failure at a crosshead speed of 1 mm/min using an Instron universal testing machine. Data were analyzed using two-way ANOVA and Fisher's PLSD test (p<0.05). RESULTS: Control values ranged from 45.1 MPa for Pertac II to 71.5 MPa for APX. Untreated blood contamination resulted in resin-resin bond strengths of only 1.0-13.1 MPa. Rinsing raised bond strengths to over 40 MPa for each material. Use of an adhesive further increased bond strengths except for Pertac II. SIGNIFICANCE: Rinsing blood from contaminated surfaces increases the resin-resin bond strength significantly and the application of an appropriate adhesive increases the bond strength to control levels.

Analysis of Variance↗

Oldies but goodies.

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Dental Materials↗

Irradiance effects on the mechanical properties of universal hybrid and flowable hybrid resin composites.

OBJECTIVES: A potential problem with high-intensity lights might be failure of polymer chains to grow and cross-link in a desired fashion, thereby affecting the structure and properties of the polymers formed. The purpose of this study was to evaluate mechanical properties of resin composites polymerized using four different light-curing units. METHODS: A conventional quartz-tungsten-halogen (QTH) light, a soft-start light, an argon-ion laser, and a plasma-arc curing light were used to polymerize disk-shaped (9.0mm diameter x 1.0 mm high) and cylinder-shaped (4mm diameter x 8 mm high) specimens of a universal hybrid and a flowable hybrid composite. Biaxial flexure strength, fracture toughness, hardness, compressive strength, and diametral tensile strength were determined for each composite. RESULTS: The use of the plasma-arc curing light, a high-intensity light, resulted in significantly lower hardness for the universal hybrid composite compared with the hardness obtained using the conventional QTH and the soft-start units. Hardness was the only mechanical property that was adversely affected by the use of a high-intensity light. SIGNIFICANCE: High-intensity lights might affect some resin composite mechanical properties, but this effect cannot be generalized to all resin composites and all properties.

Composite Resins↗

Curing light intensity effects on wear resistance of two resin composites.

This in vitro study evaluated the wear resistance of resin composite polymerized using four different light-curing systems. For this, a well-defined cylindrical cavity preparation (4.0 mm in diameter x 3.0 mm in depth) was made in a ceramic block (n=4 per material/light condition). Uncured material, either a universal hybrid composite (Herculite XRV) or a flowable hybrid composite (Revolution Formula 2), was packed and light-cured from the top surface only with one of the four light-curing units: 1) a conventional quartz-tungsten-halogen light, 2) a soft-start light, 3) an argon-ion laser or 4) a plasma-arc curing light. After storing the specimens in deionized water at 37 degrees C for 24 hours, the excess cured material was ground through successive grits up to a final 1200-grit SiC abrasive. The specimens were placed in deionized water at 37 degrees C for an additional 24 hours. Wear simulation was performed using a four-station Leinfelder-type three-body wear device. A slurry of water and unplasticized polymethylmethacrylate beads, simulating an artificial food bolus, was placed on the surface of each resin-composite-restored ceramic block. The entire cycling procedure was carried out 400,000 times. Impressions of each resin composite surface were taken with polyvinylsiloxane and epoxy replicas were made. Wear analyses were conducted by generating tracings across the worn surface of epoxy replicas using profilometer scans. For the universal hybrid composite and the flowable hybrid composite, the lowest wear occurred in specimens that were cured using the conventional quartz-tungsten-halogen light, and the highest wear was detected on those specimens made using the argon-ion laser. For both resin composites, the mean wear for specimens cured using the argon-ion laser was significantly higher than that of the specimens cured with the three other lights, which were statistically similar.

Analysis of Variance↗