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Harsh Mohan

Publications and source records attributed to Harsh Mohan.

At least 37 records · Page 2Linked to original sources
PubMed2005

FNAC in a case of NHL presenting initially as nodal infarction.

Lymph node infarction is rare and can occur in either nonneoplastic or neoplastic conditions. Fine needle aspiration cytology (FNAC) of infarction preceding lymphoma has not been described earlier. A 26-year-old male, was referred to the cytology laboratory for FNAC of bilateral axillary lymph nodes. FNA smears showed uniform looking ghost cells. There were no viable cells. A biopsy was advised which also showed extensive coagulative necrosis. Five weeks later, right cervical lymph nodes also appeared and FNA smears showed discrete monomorphic population of immature lymphoid cells. A cytologic diagnosis of infarction in a case of non-Hodgkin's lymphoma (NHL) was made and subsequently confirmed by histopathologic examination. Our case indicates that such cases should be followed up closely and repeated aspirations should be done to prevent a delayed diagnosis of lymphoma.

Adult↗
PubMed2005

Myxolipoma of the epiglottis in an adult: a case report.

Lipomas of the larynx are rare. When they do occur, they are important because some require that the surgeon perform a tracheotomy to prevent a fatal airway obstruction. We report a case of myxolipoma-that is, a lipoma with foci of myxomatous degeneration-of the epiglottis in a 56-year-old woman. We successfully treated the tumor with intubation and surgery; tracheotomy was not necessary. To the best of our knowledge, myxolipoma of the epiglottis in an adult has not been previously reported in the English-language literature.

Epiglottis↗
PubMed2005

Choriocarcinoma with negative urinary and serum beta human chorionic gonadotropin (betaHCG)--a case report.

This was a rare case where a patient presented clinically as a case of post abortal sepsis and ultrasound showing the picture of an intramural degenerating fibroid. Her serum and urine both were negative for beta human chorionic gonadotropin (betaHCG). Patient succumbed to choriocarcinoma 1 month later. Failure to detect urinary and serum betaHCG lead to maternal mortality due to the choriocarcinoma. The failure to detect, certain degradation products of HCG which may predominate in gestational trophoblastic neoplasia, by many common HCG testing kits lead to the error of diagnosis. Only 3 of the 7 common commercial serum HCG tests appropriately detects nicked HCG and its free betaHCG, DPC immulite assay, being the most sensitive method. Though of rare occurrence, this awareness is important for diagnosis and follow-up of gestational trophoblastic neoplasia and could have been life saving in our case.

Adult↗
PubMed2005

Subcutaneous angiolipomas: a clinicopathological study of 12 cases.

A total of 12 cases of angiolipomas were received over a period of 2 years and comprised 13% of all lipomatous tumors. There were eleven males and one female. Pain/tenderness was the presenting feature in 11 of the cases and in all the cases, the tumors were located on upper extremities or trunk. Grossly, the tumors were encapsulated and histologic examination revealed fibrin thrombi in many capillaries, in all cases. None of these tumors were infiltrating into the surrounding skeletal muscle or soft tissue.

Adult↗
PubMed2004

Recurrent diffuse lipomatosis of the neck--a case report.

Diffuse lipomatosis is a rare disorder of adipose tissue occurring in young people . It has a predilection for trunk and proximal extremities where it presents as poorly circumscribed overgrowth of fatty tissue. Definite diagnosis is established by histological examination of tumor. Though it attains extensive size and has a high tendency to recur, the clinical course is benign.

Child↗
PubMed2004

Adrenocortical carcinoma: diagnosis by fine needle aspiration cytology.

Two cases of adrenal cortical carcinoma are described, wherein the diagnosis was established by fine needle aspiration cytology (FNAC). FNAC is increasingly being accepted as a means of diagnosis of adrenal cortical carcinomas. In yester years the diagnosis was established largely on post-operative histopathology. Adrenal cortical carcinomas are rare and account for less than 0.05% of all malignant neoplasms. Adrenal gland has become frequent target of needle biopsies with the availability of sensitive imaging techniques and better localization. Currently, needle biopsy is the only non-surgical means of obtaining a diagnosis in patient with adrenal mass. We present two cases of adrenal cortical carcinoma diagnosed on fine needle aspiration cytology (FNAC).

Adrenal Cortex Neoplasms↗
PubMed2003

Massive ovarian oedema: report of two cases.

INTRODUCTION: Massive ovarian oedema is a rare entity characterized by accumulation of oedema fluid in ovarian stroma. Clinically it mimics solid ovarian neoplasm and thus requiring histopathological examination to rule out malignancy. CASE REPORT: Two cases of massive ovarian oedema are presented and the pathogenesis and management is being discussed.

Adult↗
PubMed2003

Squamous cell carcinoma of the prostate.

Squamous cell carcinoma of the prostate is rare, accounting for 0.5-1% of all prostatic cancers. It is highly aggressive and responds poorly to any mode of therapy. We present a case of squamous cell carcinoma of the prostate that developed in a patient with prostatic adenocarcinoma following radiation therapy.

Adenocarcinoma↗
PubMed2003

Induction & resolution of lobar pneumonia following intranasal instillation with Klebsiella pneumoniae in mice.

BACKGROUND & OBJECTIVES: Pneumonia caused by Klebsiella pneumoniae is important due to its high morbidity and mortality, especially in context of nosocomial infections. Many experimental studies have focused on the induction and progression of infection till it peaks, but the process of resolution has not been described. In the present study, we successfully attempted to establish an acute respiratory tract infection model in BALB/c strain of mice with K. pneumoniae employing a simple, reproducible intranasal instillation method. METHODS: Experimental pneumonia was induced by two strains of K. pneumoniae in BALB/c mice following intranasal instillation, and the course of pneumonia was studied by bacteriological and histopathological evaluation of the lung tissue. RESULTS: Both the strains were similar in their ability to induce infection which peaked on day 3, post infection. However, a strain dependent difference in relation to bacterial load and the process of resolution was observed. INTERPRETATION & CONCLUSION: The present study provides a model of lobar pneumonia produced by K. pneumoniae which can be useful for studying therapeutic and preventive interventions.

Administration, Intranasal↗
PubMed2003

Behçet's disease with relapsing cutaneous polyarteritis-nodosa-like lesions, responsive to oral cyclosporine therapy.

Cutaneous polyarteritis-nodosa-like lesions are rarely described in Behcet's disease. We report a case of recurrent cutaneous polyarteritis-nodosa-like (C-PAN-like) lesions in Behcet's disease with multiple deep vein thromboses as part of systemic vasculitis. The mucocutaneous manifestations responded to prednisolone; however, C-PAN-like lesions were refractory and responded to oral cyclosporine. We conclude that C-PAN-like lesions may be marker of severe disease and require intense immunosuppressive therapy.

Adolescent↗
PubMed2003

Peripheral nerve sheath tumours--a short series with some uncommon variants.

Peripheral nerve sheath tumours are rarely malignant (0.001%), such malignant peripheral nerve sheath tumours (MPNST) are more common in upper extremities than in head and neck. Chondroid differentiation in benign peripheral nerve sheath tumours and melanotic schwannoma are very uncommon. In a retrospective analysis of 25 peripheral nerve sheath tumours over a period of two years, we reported two MPNST one of which was in a parapharyngeal location while the other MPNST showed melanotic differentiation. Similar melanotic differentiation was also seen in another benign melanotic schwannoma. Chondroid differentiation in a schwannoma was also observed which is usually documented in MPNST.

Adolescent↗
PubMed2003

Primary angiosarcoma of the spleen--a case report.

Primary splenic angiosarcomas are rare neoplasms. They have aggressive behavior that frequently present with hematological abnormalities and metastatic disease. The diagnosis can only be made at surgery. Prognosis of this disease is poor. We present a rare case of primary splenic angiosarcoma with metastases in liver.

Hemangiosarcoma↗
PubMed2003

Xanthogranulomatous oophoritis and salpingitis: late sequelae of inadequately treated staphylococcal PID.

We describe the case of a 42-year-old woman who was a follow-up case of incompletely treated pelvic inflammatory disease, and presented with menorrhagia and bilateral ovarian masses. Subtotal hysterectomy with bilateral salpingo-oophorectomy was performed. Purulent material was obtained from the cystic masses, which grew Staphylococcus aureus. Histological examination of right-sided cystic mass revealed a simple cyst of the ovary. Left sided tuboovarian mass revealed the presence of lipid filled macrophages with lymphocytes, plasma cells and neutrophils; this established the diagnosis of xanthogranulomatous salpingitis and oophoritis. The case is of interest in view of the rarity of this condition; five cases of xanthogranulomatous salpingitis and oophoritis have been reported in the world literature till date.

Adult↗