Biomedical subjects

Harumitsu Murohashi

Publications and source records attributed to Harumitsu Murohashi.

6 recordsLinked to original sources

PubMed2006

An ERP study of visual change detection: effects of magnitude of spatial frequency changes on the change-related posterior positivity.

In event-related brain potential (ERP) studies using a visual S1-S2 matching task, change stimuli elicit a posterior positivity at around 100-200 ms. In the present study, we investigated the effects of magnitude of spatial frequency changes on change-related positivity. Each trial consisted of two sequentially presented stimuli (S1-S2), where S2 was either (1) the same as S1 (i.e., NO-change, p=.40), (2) different from S1 in spatial frequency only (SF-change, .40), (3) different in orientation only (OR-change, .10), or (4) different in both spatial frequency and orientation (BOTH-change, .10). Further, three magnitude conditions (Large, Medium, and Small) were used to examine the effect of the magnitude of the spatial frequency change. Participant's (N=12) task was to respond to S2 with a change in orientation (from vertical to horizontal, or from horizontal to vertical) regardless of the spatial frequency of the stimulus. Changes in the spatial frequency elicited change-related positivity at a latency range of about 120-180 ms, which was followed by a central negativity (N270) and a late positive component (LPC). The amplitude of the change-related positivity tends to be enhanced as the magnitude of the change is increased. These results support the notion that the change-related positivity reflects memory-based change detection in the human visual system.

Adult↗

PubMed2006

Probability-independent and -dependent ERPs reflecting visual change detection.

In ERP studies, two posterior components with different polarities have been identified as ERP correlates of visual change detection. To compare these components in terms of sensitivity to the preceding stimulus sequence, two peripheral stimuli of different colors (red and blue) were presented with equal (50:50) or different probabilities (20:80 or 80:20), while 12 participants performed shape discrimination at a central location. A posterior positivity at around 90-140 ms was observed with similar amplitude to all stimuli immediately preceded by a different stimulus. In contrast, a posterior negativity at around 140-180 ms was observed to increase in amplitude with increasing number of preceding different stimuli. These results suggest the existence of probability-independent and -dependent change processing in the human visual system. The functional significance is discussed in terms of memory-based comparison and stimulus-specific refractoriness.

Adult↗

PubMed2005

Neural correlates of pre-attentive and attentive processing of visual changes.

To identify electrophysiological correlates of pre-attentive and attentive processing of visual changes, we compared event-related brain potentials in response to color changes at attended and unattended spatial locations using a visual S1-S2 matching task. The results showed that compared to no change, change stimuli elicited occipito-temporal positivity at around 100-160 ms (change-related positivity) and subsequent central negativity at around 220-300 ms (N270). Change-related positivity was observed in response to changes at both attended and unattended locations, while N270 was observed only when attention was directed to the location of the changes. These results suggest that change-related positivity reflects the pre-attentive processing of visual changes and N270 reflects the attentive processing of visual changes in the human brain.

Adult↗

PubMed2005

Discrepancy between feedback negativity and subjective evaluation in gambling.

Feedback negativity is a negative event-related potential elicited by feedback indicating incorrect performance or monetary loss. It is unclear whether this negativity is elicited by neutral feedback (e.g. a draw in gambling) or is affected by the subjective rating of punishment. To investigate these issues, we performed a modified and computerized game of 'rock-paper-scissors' as a gambling task and measured feedback negativity in response to feedback indicating the outcome, which was accompanied by a monetary reward. The data demonstrated that feedback negativity was elicited not only by a monetary loss but also by an even outcome and was independent of the magnitude of monetary loss. Our results suggest feedback negativity is not always specific to both monetary loss and subjective rating of punishment.

Adult↗

PubMed2005

Independent processing of visual stimulus changes in ventral and dorsal stream features indexed by an early positive difference in event-related brain potentials.

In event-related brain potential (ERP) studies of brain activity using a visual S1-S2 matching task, change stimuli elicit a posterior positive component with a latency of 100-200 ms. To elucidate the hierarchical organization of the processing of a visual stimulus change based on multiple stimulus features, ERPs were recorded in 12 participants performing an S1-S2 matching task with stimuli defined by color (mediated by the ventral stream) and motion direction (mediated by the dorsal stream). Each trial consisted of two sequentially presented stimuli (S1-S2), where S2 was either (1) the same as S1 (i.e., no change), (2) different from S1 in color only (color change), (3) different in motion direction only (motion direction change), or (4) different in both color and motion direction (color-motion direction change). These trials were presented in random order with equal probability, and the participants were asked to respond to one of these trials in separate blocks. Relative to the no-change stimulus, the three types of change stimuli elicited posterior positivities. The scalp-topography of change positivities differed according to the feature changed. In addition, the amplitude and scalp-topography of change positivities in response to a conjunction change were the respective sums of those in response to changes in the corresponding single features. These results suggest that the change detection system reflected by the change positivity is separate for each feature dimension, and these operate independently.

Adult↗

PubMed2005

Positive difference in ERPs reflects independent processing of visual changes.

To elucidate the nature of the processing of visual stimulus changes, ERPs were recorded while 12 participants performed an S1-S2 matching task with multifeature stimuli. Each trial consisted of two sequentially presented stimuli (S1-S2), where S2 was either the same as S1, different from S1 only in color, different only in shape, or different in both color and shape. The four trial types were presented in random order with equal probability, and participants responded to one of these types in separate blocks. Relative to the no-change stimuli, the change stimuli elicited posterior positivity with different topography according to changing features ranging from 100 to 180 ms in all tasks. The amplitude and topography of the positivity in response to the both changes were the respective sums of those to changes in the corresponding single features. These results suggest that a feature-specific change detection system exists in the human visual system.

Adult↗