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Biomedical subjects

Harun Doğru

Publications and source records attributed to Harun Doğru.

24 records · Page 2Linked to original sources
PubMed2003

Asymptomatic IgE mediated food hypersensitivity in patients with nasal polyps.

The aim of this prospective study is to compare the prevalence of atopy in patients afflicted by nasal polyps with the atopy prevalence in healthy volunteers without nasal polyps, since systemic allergy and allergy in the nasal mucosa are still being debated as underlying causes for nasal polyps. Thirty-four cases with nasal polyposis without asthma and history of allergy or atopic disease were enrolled in the study and compared with 20 healthy volunteer controls in respect to asymptomatic food hypersensitivity. Hypersensitivity for 48 kinds of commonly consumed food in Turkey was investigated by an epicutaneuos prick test, Multi-Test II (Lincoln Diagnostic, Inc, USA), using a special applicator. The food allergy test was positive in 25 out of the 34 cases with nasal polyps and in 6 out of the 20 controls. The difference between the two groups was statistically significant (chi2 = 0.000, p < 0.001). The number of skin tests with positive results in patients with nasal polyps ranged from 1 to 37 (mean +/- S.D. = 10.0 +/- 7.9), whereas in the control subjects the range was 1 to 10 (mean +/- S.D. = 4.0 +/- 3.3). The difference in the number of food reactions was also statistically significant. Asymptomatic food hypersensitivity, being immunologically mediated, may be a triggering factor for the pathogenesis of nasal polyps. Therefore, treatment of asymptomatic food allergy in patients with nasal polyps may alleviate symptoms, slow the progress of nasal polyps and prolong the disease-free interval after polypectomy.

Adolescent↗
PubMed2003

[The correlation between computed tomography findings of the paranasal sinuses and the symptoms of acute sinusitis].

OBJECTIVES: We investigated the relationship between symptoms, coronal paranasal computed tomography (CT) findings and anatomic variations in patients with acute sinusitis. PATIENTS AND METHODS: The study included 44 patients (23 females, 21 males; mean age 35 years; range 21 to 74 years) whose diagnosis was acute sinusitis by history and physical examination. A comprehensive inquiry into the symptoms was made and coronal paranasal CT scans were obtained in all the patients. Correlations were sought between symptom scores, CT scores, and anatomic variations. RESULTS: No correlations were found between anatomic variations and CT scores. Total symptom scores did not correlate with CT scores. A statistically significant correlation existed only between headache and CT scores. The most commonly affected sinuses were maxillary sinuses (73%), followed by posterior ethmoidal sinuses (60%). CONCLUSION: Our data suggest that routine CT evaluations are superfluous in acute sinusitis.

Acute Disease↗
PubMed2003

[The adverse effect of gas formation on prognosis in a patient with deep neck infection].

A seventy-one-year-old woman was hospitalized with a suspicion of deep neck infection and poor general health. She had been receiving treatment for hepatitis, diabetes mellitus, and cardiac failure and had a history of tooth ache and severe neck pain lasting for the past 10 days. She had been admitted to another center where she had received antibiotic treatment for five days for widespread swelling in the neck and lower extremities, fatigue, and difficulty in breathing and swallowing. Upon admission, computed tomography showed gas formation in the neck and facial regions. Prompt abscess drainage was performed and intense treatment with antibiotics was continued. Despite all efforts, the patient died on the second day of hospitalization from cardiopulmonary arrest. This case emphasizes how urgent drainage is when gas formation is detected in deep neck infections, with inevitable poor prognosis with antibiotic treatment alone.

Aged↗
PubMed2002

Nasal septal clip (Ciğdem clip).

We report the use of a nasal septal clip. We believe that this instrument is more easily inserted and removed when compared with the classical nasal packs.

Equipment Design↗