Biomedical subjects

Hasan Bakirtaş

Publications and source records attributed to Hasan Bakirtaş.

7 recordsLinked to original sources

PubMed2005

Rib resection for live-donor nephrectomy.

INTRODUCTION: Living-related kidney transplants yield more favorable results than cadaveric kidney transplant. Although multiple techniques have been described for living-related donor nephrectomy, operation is generally performed subcostally in lateral decubitis position or by an 11th or 12th rib resection. Recently laparoscopic donor nephrectomy is getting popular. The aim of this study is to determine the rib resection increase the morbidity or not. MATERIALS AND METHODS: Between 1997 and 2004 in our center 118 living donor nephrectomies were performed. 15 of these patients did not come to follow-up controls. This study consists of 103 patients: 11th rib resection (30 patients) determined as group I, 12th rib resection (52 patients) determined as group II, subcostal incision (21 patients) determined as group III. All these three groups were compared with each other according to operation time, pleural or peritoneal defect, pneumothorax, blood transfusion, wound infection, length of hospital stay, postoperative analgesic requirement, return to threshold activities and incisional hernia. RESULTS: Patients whose 11th rib was removed had the shortest operation time. But pain due to surgery continued more than others in this group of patients. The risk of developing incisional hernia was seen most in patients who had subcostal incision. In this group of patients incidence of incisional hernia was 4 (19%). None of the patients had wound infection. We also did not experience any pneumothorax and blood transfusion requirement. Peritoneal or pleural opening occurred in 4 out of 103 patients accidentally and there was no difference between groups. There was also no difference between groups in terms of returning back to daily activation. CONCLUSION: Morbidity of nephrectomy done with removal of 12th rib was less compared with other groups. Resection of 11th should be reserved for patients with high residing kidneys and also for those with a polar artery of the upper pole.

Adult↗

PubMed2005

Routine frozen-section biopsy from the surgical bed should be performed during nephron-sparing surgery for renal cell carcinoma.

OBJECTIVE: It has been reported in recent studies that nephron-sparing surgery (NSS) is as effective as radical nephrectomy (RN) for pT1a and pT1b renal cell carcinoma (RCC). In order to decrease the rate of tumor recurrence, resection of a small amount of normal parenchyma surrounding the tumor is widely recommended. Although a 0.5-1.5-cm wide resection margin is recommended no agreement has been reached concerning the thickness of the surgical margin. In this study we tried to determine whether routine frozen-section biopsy from the surgical bed is mandatory during NSS for RCC. MATERIAL AND METHODS: The study involved 19 renal units of 18 patients who underwent partial nephrectomy for solid renal tumors (<7 cm) at different centers in Ankara. Hypothermic ischemia was instituted after placing the kidney in an intestinal bag full of ice slush and cross-clamping the renal artery. In all cases an approximately 1-cm margin of normal tissue was removed with the tumor. Then, intraoperatively, at least three frozen-section biopsies were taken from the surgical bed to determine the surgical margin. If the biopsy was positive, RN was performed. RESULTS: All patients were staged as pT1a or pT1b according to the 2002 TNM classification. The average tumor size was 3.8 cm. In three cases we performed RN due to positive surgical margins. Surgical margins were negative in 16 tumors, with a mean negative margin size of 5 mm (range 2-11 mm). One patient died of a non-cancer-related cause. The mean distance to the renal capsule was 7 mm (range 1-11 mm). Seventeen patients were followed up for 18 months with no local or systemic recurrence. CONCLUSION: In some cases an approximately 1-cm margin is not sufficient to ensure a negative margin and frozen-section biopsies must be taken from the tumor bed, even if it seems normal macroscopically.

Adult↗

PubMed2005

Subureteral dextranomer/hyaluronic acid copolymer injection for vesicoureteral reflux in transplant candidates.

BACKGROUND AND PURPOSE: Endoscopic subureteral injection of tissue-augmenting substances has become an alternative to antibiotic prophylaxis and open surgery for the management of vesicoureteral reflux (VUR). Several injectable materials have been tried for this purpose. In this study, we tried to determine the efficacy of dextranomer/hyaluronic acid copolymer (Dx/HA) injection for the treatment of VUR in renal-transplant candidates. PATIENTS AND METHODS: A total of 21 transplant candidates (29 ureteral units; 13 females, 8 males) with a mean age of 20.2 years (range 14-26 years) underwent endoscopic correction of VUR with Dx/HA. Diagnosis of VUR was made by voiding cystourethrography. The efficacy of the treatment was assessed with voiding cystourethrography at 3 months and 1 year postoperatively. Renal transplantation with living related donor organs was performed in 11 of the 21 patients. RESULTS: Endoscopic treatment was performed without complication in all cases. Higher success rates were obtained in patients with low-grade reflux, the overall success rate in the series being 82.7%. The mean follow- up after renal transplantation was 21.8 months (range 5-45 months). In one patient, reflux recurred after renal transplantation and was treated successfully by a repeat Dx/HA injection. The urine cultures of all patients remained sterile. CONCLUSION: Transplant candidates with VUR can be treated with Dx/HA, which cured the majority of our patients after one or two treatments with few low side effects. Endoscopic subureteral injection of Dx/HA has become an alternative treatment for VUR in transplant candidates. Long-term results are needed before making a final statement about its value.

Administration, Intravesical↗

PubMed2005

Malignant fibrous histiocytoma arising from the renal capsule.

We report a case of malignant fibrous histiocytoma arising from the renal capsule which is a rare condition. The patient was treated with surgical excision of the tumor including the renal capsule and subsequent radiotherapy of 6,600 rad. No recurrence was detected 15 months after surgery.

Aged↗

PubMed2003

Comparison of two methods--Mmathieu and Snodgrass--in hypospadias repair.

INTRODUCTION: Perimeatal flap (Mathieu) and tubularized incised-plate (Snodgrass) methods were compared regarding success rate, postoperative complications, and cosmetic appearance in primary and recurrent distal hypospadias cases with normal urethral plates. PATIENTS AND METHODS: Between 1995 and 2001 Snodgrass-type repair was done in 32 primary and in 24 recurrent hypospadias cases (total 56 patients; mean age 5.8, age range 3-17 years), and Mathieu-type repair was done in 33 primary and in 21 recurrent distal hypospadias cases (total 54 patients; mean age 5.2, age range 2-19 years). There was no statistically significant difference between groups regarding demographics. Patients with primary hypospadias either without or with minimal chordee and patients with recurrent hypospadias only with a normal urethral plate were included in the study. The mean postoperative follow-up period was 24 months. RESULTS: Meatal stricture formation, fistula formation, wound dehiscence, and flap necrosis were seen in 2, 4, 4, and 2 patients, respectively, treated with the Mathieu technique and in 5, 4, 3, and 0 patients, respectively, treated with the Snodgrass technique. Wound dehiscence and flap necrosis were seen less frequently, whereas meatal stenosis was more common in the Snodgrass group (p < 0.05, p < 0.05, and p > 0.05, respectively; chi(2) test). There was no difference between groups regarding fistula formation. Mean hospital stay, time to stent withdrawal, and urinary diversion period were shorter in the Mathieu group (7.5 +/- 1.19 vs. 5.7 +/- 1.38 days, 7.1 +/- 0.67 vs. 5.4 +/- 0.85 days, and 14.1 +/- 1.17 vs. 10.2 +/- 1.72 days, respectively; p < 0.001 for all). The total success rates were similar (78.6% in the Snodgrass group and 77.8% in the Mathieu group). Cosmetic appearance was highly satisfactory in the Snodgrass group. CONCLUSIONS: We believe that the Snodgrass method should be preferred for primary and recurrent hypospadias cases without chordee or with minimal chordee and with a normal urethral plate due to its lower complication rate and its satisfactory cosmetic appearance. However, when a healthy urethral plate is not available, Mathieu-type repair can be preferred.

Adolescent↗

PubMed2002

Clinical experiences with different one-staged surgical methods for primary hypospadias cases.

The success of various types of operations for primary hypospadias was assessed taking the location of meatus and the degree of chordee as the basis. Totally 258 patients with primary hypospadias were operated: 94 by meatal and urethral advencement, 110 by perimeatal flap and tube repair and 54 by preputial flap. The rates of success in cases with meatal advencement, perimeatal flap and preputial flap were found as 88%, 81% and 66% respectively. The success of treatment in hypospadias cases is closely related to the age of the patient, the experience of the surgeon and the choice of an appropriate method. However, the presence of chordee and the proximally located meatus are among the leading factors that influence the rate of success.

Child↗

PubMed2002

A comparison of two different incisional approaches in the surgical treatment of renal cell carcinomas.

Radical nephrectomy is the golden standard in the surgical treatment of renal cell carcinomas. In radical nephrectomy, the type of incision that is preferred is very important for the success of surgery. Within the last 6 years, we operated 76 renal cell carcinoma cases in our department. In these operations, we used either extra peritoneal flank incision (EFI) or transabdominal subcostal incision (TASI). In this study, we decided to compare the effects of these two incisional approaches on the clinical prognosis of the disease. We realized that TASI was our method of choice in tumors with high stage and large diameters. EFI on the other hand, was chosen for the cases with low stage. Both methods did not differ regarding intraoperative and postoperative complications. We concluded that in the treatment of renal cell carcinoma, the type of incision should be chosen according to the clinical picture of the disease and the experience of the surgeon in order for the operation to be successful.

Adult↗