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Biomedical subjects

Henry J Schiavello

Publications and source records attributed to Henry J Schiavello.

3 recordsLinked to original sources

Wernicke's encephalopathy with hyperemesis and ketoacidosis.

BACKGROUND: Avitaminosis can result from the acute malnutrition associated with prolonged pregnancy-related hyperemesis. Serious complications may arise from thiamine deficiency under these circumstances. CASE: We review the relevant literature and describe a case with central nervous system involvement presenting with typical manifestations of Wernicke's encephalopathy, apparently precipitated by a combination of hyperemesis gravidarum, diabetic ketoacidosis, and intravenous glucose administration. CONCLUSION: While this life-threatening complication is rare, it is important for all who care for obstetric patients to be aware of it and alert to its development. Early recognition is critical given the need to treat affected women expeditiously to help avoid potentially fatal adverse consequences. Prophylactic thiamine supplementation should be considered in the care of gravidas with hyperemesis.

Adult↗

Manual removal of the placenta and postcesarean endometritis.

OBJECTIVE: To determine if manual vs. spontaneous delivery of the placenta at cesarean section affects the rate of postoperative endometritis and amount of blood loss. STUDY DESIGN: A prospective, randomized study was carried out on patients who had cesarean delivery assigned either to spontaneous delivery of the placenta (group 1) or manual removal (group 2). We excluded patients undergoing emergency cesareans and those with possible placenta accreta or evidence of preexisting infection. Outcome measures (frequency of endometritis and quantitative decrease in hemoglobin) were compared for the two groups. RESULTS: Study criteria were met for 375 subjects: 177 in group 1 and 198 in group 2. Endometritis was diagnosed in 1.7% of the former and 2.5% of the latter. The change in hemoglobin, reflecting operative blood loss, was similar in both groups (-1.81 and -1.72 g/dL, respectively). CONCLUSION: We found no significant difference in either postoperative endometritis or blood loss regardless of the means used to effect delivery of the placenta. The frequency of febrile morbidity in our study cases was considerably lower than heretofore reported.

Adult↗

Concurrent appendicitis and ectopic pregnancy. A case report.

BACKGROUND: Ectopic pregnancy is infrequently encountered together with appendicitis. Since 1960, 21 such cases have been reported. CASE: A 32-year-old, Hispanic woman presented with signs and symptoms of an acute surgical abdomen. Preoperatively, the diagnoses of both ectopic pregnancy and acute appendicitis were entertained. On surgical exploration, a ruptured appendix and an unruptured left-sided ectopic pregnancy were found. CONCLUSION: The possibility of multiple pathologic disorders should always be considered in a patient with an acute surgical abdomen, especially during pregnancy. Evidence exists of a possible association between ectopic pregnancy and appendicitis in terms of a common pathogenic mechanism.

Abdominal Pain↗