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Biomedical subjects

Hideki Masuda

Publications and source records attributed to Hideki Masuda.

59 records · Page 4Linked to original sources

Prophylactic transileocolic obliteration of esophageal varices after balloon-occluded retrograde transvenous obliteration of gastric varices with a gastrorenal shunt.

Several non-surgical techniques have been developed to treat esophagogastric varices that occur secondary to portal hypertension, including those performed endoscopically or with interventional radiologic therapies. In patients with large gastric fundal varices and associated gastrorenal shunting, controversy still remains in defining the most appropriate non-surgical intervention. Balloon-occluded retrograde transvenous obliteration has been shown to be one effective treatment for gastric varices in these instances. However, in the population treated in this manner, the inhibition of subsequent esophageal varices is essential. We report a patient with gastric fundal varices that were successfully treated using balloon-occluded retrograde transvenous obliteration and in whom prophylactic transileocolic obliteration of esophageal varices was additionally performed. This 46-year-old man was diagnosed with severe gastric varices and gastrorenal shunting with only mild esophageal varices. Five years after therapy, the patient demonstrates no evidence of recurrence of either gastric or esophageal varices and has remained otherwise healthy.

Digestive System Surgical Procedures↗

Incidence of bile leakage after three types of hepatic parenchymal transection.

BACKGROUND/AIMS: Bile leakage is a major morbidity associated with hepatectomies. No study has been performed correlating various methods of liver transection to incidences of bile leakage. METHODOLOGY: The 89 patients with hepatocellular carcinoma who received hepatectomy were classified into 3 groups according to the specific method of liver resection: cavitron ultrasonic surgical aspirator (CUSA), microwave tissue coagulation (MTC), and clamp crushing (CC). Comparisons in the incidences of bile leakage and length of hospital stay were made among these groups. RESULTS: The CC group showed a significantly lower incidence of bile leakage than the MTC group (3% vs. 27%, P = 0.03). In the median postoperative hospitalization length, the CC group demonstrated a significantly shorter period than that in the MTC group (25 vs. 35 days, P = 0.03). No significant differences were found for operation time, amount of blood loss or resected tumor size in the 3 groups. CONCLUSIONS: In view of the incidence of bile leakage, CC is a favorable technique for hepatectomy.

Adult↗

Usefulness of bipolar scissors for rectal cancer surgery with autonomic nerve preservation.

BACKGROUND/AIMS: Pelvic autonomic nerve preservation for rectal cancer has become more common in recent years. Therefore, we evaluated the usefulness of bipolar scissors for this procedure. METHODOLOGY: This study included 30 consecutive patients with lower rectal cancer who underwent pelvic autonomic nerve preservation at our hospital between April 1998 and August 2001. The bipolar scissors group comprised 10 patients who received the procedure using bipolar scissors, while the conventional group included 20 patients who received the procedure without the use of bipolar scissors. The two groups were compared in terms of operating time, blood loss, postoperative urinary and sexual function. RESULTS: Blood loss in the bipolar scissors group was 394.4 +/- 201.8mL, which was a significantly lower volume than that in the conventional group (881.8 +/- 582.9ml) (p=0.0049). All the patients in the bipolar scissors group (10/10=100%) and 19 cases in the conventional group (19/20=95.0%) answered that they were satisfied with the results of their voiding function. In the bipolar scissors group, 100% were capable of erection (5/5) and 80.0% preserved ejaculation (4/5). In the conventional group, 100.0% (10/10) and 77.8% (7/9) preserved erection and ejaculation, respectively. CONCLUSIONS: The use of bipolar scissors is quite beneficial when patients with rectal cancer receive pelvic autonomic nerve preservation.

Aged↗

Recording of surgery with two crane-type tripods and video cameras.

At medical meetings, a video-recorded surgical procedure can be more persuasive than an oral or poster presentation. Because operating rooms generally have limited space, video setups must be efficient and effective. Patients undergoing hepatectomy and rectal resection were recorded using two sectional crane-type tripods and video cameras placed in different positions. Both small crane-type tripods and video cameras could record surgical procedures from different angles and were easily controlled. Surgical procedures by the surgeon and first assistant were recorded independently. Videotaping surgical procedures with two video cameras can make presentations at medical meetings more effective.

Hepatectomy↗

Microsatellite instability in poorly differentiated colorectal adenocarcinoma, particularly in relation to two subtypes.

BACKGROUND/AIMS: There have been a few reports indicating the characteristics of poorly differentiated colorectal adenocarcinoma by dividing it into subtypes. However, we have not found any reports describing microsatellite instability (MSI) of each subtype. In this study, we elucidated the clinicopathological features of subtypes in the poorly differentiated adenocarcinoma, especially the relationship between MSI and each subtype. METHODOLOGY: The present study included 28 cases with poorly differentiated adenocarcinoma. The 28 cases were classified into two groups; the solid group and the non-solid group. For each group, the clinicopathological aspects and MSI were examined. RESULTS: No significant differences were noted between the solid group and the non-solid group in terms of clinicopathological findings excluding male/female ratio. The 5-year survival rate of the solid group (38.5%) was significantly higher than that of the non-solid group (0.00%) (p=0.0013). The ratio of cases with MSI-H in the solid group (80.0%=12/15) was significantly higher than that of the non-solid group (30.8%=4/13) (p=0.0087). CONCLUSIONS: The incidence of MSI as well as the prognosis was different between solid and non-solid type with poorly differentiated colorectal adenocarcinoma. Therefore, we think that poorly differentiated colorectal adenocarcinoma should be classified into two subtypes: solid type and non-solid type when analysis for poorly differentiated adenocarcinoma is performed.

Adenocarcinoma↗