Mucosal prolapse polyp arising on the anastomotic site or postpolypectomy site of the rectum endoscopically mimicking recurrence of adenocarcinoma.
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Biomedical subjects
Publications and source records attributed to Hideo Hattori.
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The amination of 1-n-hexanol followed by amidation was carried out in supercritical water at 380, 400, and 420 degrees C and water densities of 0.1, 0.3, and 0.5 g/cm3. The replacement of the hydroxyl group with the amino group was found to occur in 1-n-hexanol using ammonium acetate in supercritical water without the addition of a metal or an acid catalyst. The yield of the final product, N-n-hexylacetamide, increased by increasing the reaction temperature, water density, and the amount of ammonium acetate. The yield and the selectivity of N-n-hexylacetamide were 78.5% and 87.5%, respectively, in supercritical water at 400 degrees C, 0.5 g/cm3, for 10 min.
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BACKGROUND: Vacuolated cells could be encountered in neurofibroma. OBJECTIVES: Frequency and immunohistochemical feature of vacuolated cells in neurofibroma. METHODS: Sixty-two lesions of neurofibroma including five plexiform neurofibromas were re-evaluated for the search of vacuolated cells. Immunohistochemical analysis was performed for cases with vacuolated cells. RESULTS: In five cases of plexiform neurofibroma and four cases of sporadic neurofibroma with endoneurial component, presence of vacuolated cells in the endoneurial mucoid area was noted. They were immunoreactive both with S-100 protein and CD34, mostly negative for factor XIIIa and negative for epithelial membrane antigen. Vacuolated cells were found neither in the diffuse portion of plexiform neurofibroma nor in sporadic diffuse neurofibroma. CONCLUSION: Presence of vacuolated cells is a highly characteristic feature of endoneurial portion of neurofibroma. Considering immunoreactivity both with S-100 protein and CD34 in the majority of vacuolated cells, they could be regarded as to represent endoneurial precursor cells in a certain stage of differentiation to Schwann cells.
BACKGROUND: To identify and estimate the prevalence of mediastinal cysts lined by the epithelium expressing steroid receptors. METHODS: We retrieved 19 mediastinal cysts from our pathology files from 1996 to 2004, and examined estrogen receptor (ER) and progesterone receptor (PR) expressions in the cysts. RESULTS: Three paravertebral cysts, all in women, one bronchogenic cyst in a woman, nine thymic cysts, and six pericardial cysts were found in the pathology files. Paravertebral cysts were situated in the posterior mediastinum and were attached either to the left or the right of the vertebral column. All cysts were radiologically diagnosed before surgery as neurogenic tumors. They were excised by video-assisted thoracoscopic surgery. The epithelial lining of the cyst in all three cases was strongly positive for both ER and PR. A thymic cyst in one woman was weakly positive only for the ER. In all other cases, the lining was entirely negative for both ER and PR. CONCLUSIONS: Posterior mediastinal paravertebral cysts characteristically express ER and PR. They should be recognized as a distinct type of mediastinal cyst because they are biologically different from bronchogenic cysts, seem not to be infrequent, and sometimes are misdiagnosed as a neurogenic tumor.
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A 51-year-old man was admitted with hyperglycemia and a duodenal tumor. Although his glycemic control was poor, basal C-peptide levels were not suppressed. Further examination revealed a mass measuring 7.8 cm in diameter in the third portion of the duodenum. Duodenectomy revealed a slow-growing sessile tumor located near Treitz's ligament. The immunohistochemical profile of sections of the specimen revealed the presence of somatostatin. The patient's serum somatostatin was elevated to 300 pg/ml preoperatively, but was reduced to 10 pg/ml postoperatively. Glycemic control also normalized after the operation.
Lipomatous tumor is least common in the oral cavity. We present a case of atypical lipomatous tumor arising in the lower lip of an 81-year-old male. Clinical diagnosis was mucocele. The tumor measured 12 mm in diameter with a round shape. It was solid, firm, myxomatous and translucent with a small yellowish focus in the central portion. Histologically, the tumor was a circumscribed and well-encapsulated mass with prominent myxoid matrix. The central minor portion showed a well-differentiated liposarcoma. In the myxoid area, lipoblasts and large atypical cells with dense chromatin including floret-like giant cells were seen in abundance. Atypical lipomatous tumor may be indistinguishable from pleomorphic lipoma and its distinction from the latter is based on location as well as relative abundance of floret-type giant cells and lipoblasts. According to its abundance in lipoblasts over floret-like cells, pleomorphic lipoma-like area in our case could also be a part of atypical lipomatous tumor. It may be possible to interpret myxoid change in our case as to represent a superficial counterpart of myxoid malignant fibrous histiocytoma-like change reported in the retroperitoneal lesion.
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