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Biomedical subjects

Hiroyasu Okuizumi

Publications and source records attributed to Hiroyasu Okuizumi.

6 recordsLinked to original sources

Clinical factors as predictors of the risk of falls and subsequent bone fractures due to osteoporosis in postmenopausal women.

In Japan, the "bedridden state" is one of the most serious problems the aged face, and it is becoming a social problem. The main causes of the bedridden state are cerebrovascular disorders and bone fractures following falls. The purpose of this study was to predict risk factors for falls and resultant bone fracture due to osteoporosis. We explored mobility parameters for possible fall prevention. In order to examine the correlation between the risk of falling and resultant bone fracture due to osteoporosis, logistic regression analysis was performed between bone mass (independent variable) and various factors dependent variables: body mass index [BMI], body fat percentage, atherogenic index, presence of transformation-related osteoarthritis of knee, presence of transformation-related osteoarthritis of spine, maximum step length, single-leg stance with open eyes, and hip-joint flexion motion angle); predictive factors were then examined. Predictive factors were determined by the stepwise method. Subjects who could not perform the "single-leg stance with open eyes" test had a risk of falling and bone fracture 2.49 times as large as that of subjects who could. The "single-leg stance with open eyes" test may be considered a useful method for the early detection of the risk of falling and bone fracture associated with osteoporosis. As a first step to identify factors predicting the occurrence of falls and bone fractures due to osteoporosis, we intended to discover an indicator that would help to detect incipient osteoporosis.

Accidental Falls↗

[Effect of vitamin D on bone mineral density; bone strength and fracture prevention].

Although vitamin D improves bone mineral density 0.66% per year at spine site and 1.23% per year at femoral neck site, respectively, vitamin D is useful for preventing osteoporotic fractures, especially hip fractures in the elderly. Vitamin D affects microstructure and bone turnover for osteoporotic bone to become strong bone. And vitamin D improves muscle function to prevent falls in the elderly. Moreover the appropriate amount and treatment target of vitamin D must be considered for the elderly with many different diseases.

Accidental Falls↗

[Osteoporosis and physical exercise activity].

Since mechanical stress affects bone mineral density, exercise, especially weight-bearing exercise, is effective for preventing osteoporosis. Exercise activity is useful for preventing falls and fractures in the elderly. However, the appropriate amount and type of exercise must be considered for the elderly with many different diseases.

Adult↗

[Practices and strategies for the prevention of falls in the osteoporotic elderly].

Among seniors with osteoporosis, falls can cause devastating injuries such as hip fractures even with only weak impacts. We have begun a combined medical examination and educational program for exercise to prevent injurious falls. To make fall prevention practices more widespread, we hold one-day simplified fall prevention program and instruction courses for practitioners.

Accidental Falls↗