Biomedical subjects

Hong-Geun Jung

Publications and source records attributed to Hong-Geun Jung.

3 recordsLinked to original sources

PubMed2005

Myxoid clear cell sarcoma.

Clear cell sarcoma is a rare soft-tissue tumor presenting typically in the extremities of young adults. It has been also known as malignant melanoma of the soft parts because of the presence of melanin and cytoplasmic melanosomes. However, clear cell sarcoma is, at present, usually considered as a unique lesion because the t(12;22)(q13;q12) translocation is present only in clear cell sarcoma. Myxoid malignant melanoma is now a well-recognized morphologic variant of malignant melanoma. However, a myxoid variant of clear cell sarcoma has not been well described yet. We report a case of myxoid clear cell sarcoma occurring on the heel in a 22-year-old man. The tumor was composed of nests and fascicles of oval to fusiform cells with clear to pale eosinophilic cytoplasm, often separated by fibrous septa. The tumor cells were reactive for S-100 protein, HMB-45, and MART-1. Variably sized cysts lined by one or several layers of tumor cells were observed. Alcian blue and mucicarmine stains demonstrated prominent mucin deposition in the tumor stroma and especially in the lumen of the cysts. Fluorescence in situ hybridization for the Ewing sarcoma gene showed rearrangement in nearly all of the neoplastic cells.

Adult↗

PubMed2005

The role of toe flexor-to-extensor transfer in correcting metatarsophalangeal joint instability of the second toe.

BACKGROUND: The purpose of the study was to evaluate the outcome of flexor digitorum longus (FDL) transfer to the dorsum and to identify a possible continued role for this transfer in conjunction with additional surgeries for second metatarsophalangeal joint (MTPJ) instability. METHODS: We carried out a retrospective analysis on patients with second MTPJ instability for which the FDL transfer was done as the primary procedure between 1996 and 2001. The patients were examined for functional status, residual pain, and satisfaction. RESULTS: A total of 64 feet (59 patients) were evaluated, with an average followup period of 45.2 (16 to 82) months. A cross-over second toe deformity was present in 56 feet (87%) with a stage II deformity being the most common (18 feet). There also were seven feet with vertical subluxation. An additional second metatarsal Weil osteotomy was done in 29 feet (45%), a proximal interphalangeal (PIP) joint resection arthroplasty in 22 feet, and a PIP joint fusion in nine feet. At final followup of the 59 feet that were physically examined, 22 (37%) had residual second MTPJ dorsiflexion contracture and 16 feet had persistent medial deviation. The second toe was stable to stress manipulation in 46 feet (78%). The mean toe pulp to ground distance on standing was 3 mm, and strong toe grasp was possible in 45 feet. There were 20 complications in 64 feet. Twenty-five patients (29 feet) were very satisfied, 15 satisfied with minor reservations, six with major reservation, and 14 patients were unhappy with the outcome. The American Orthopaedic Foot and Ankle Society functional score was on average 82 points (47 to 100) at final followup. CONCLUSION: Although the function of the second toe improved in most patients as a result of pain relief, a substantial number of the patients in this study remained dissatisfied because of residual stiffness of the toe. The flexor tendon transfer remains an important procedure in correction of second toe instability but must be used with a full understanding of potential complications and patient dissatisfaction.

Adult↗

PubMed2004

Radiographic and biomechanical support for fibular plating of the agility total ankle.

Syndesmosis nonunion with the Agility total ankle system has been associated with adverse radiographic findings such as radiolucency and migration. We analyzed radiographs and biomechanical data to determine whether the addition of a fibular plate was associated with improved findings related to syndesmosis union compared with results when two syndesmosis screws alone were used. Radiographs for 40 consecutive ankles with the Agility total ankle system with two syndesmosis screws were compared with radiographs for the subsequent 40 consecutive total ankle replacements with an added fibular plate. When all ankles were considered, syndesmosis nonconsolidation at 6-10 weeks was associated significantly with nonunion at 5-7 months. Syndesmosis nonconsolidation at 6-10 weeks in ankles with screws alone was significantly higher than in ankles with plates. The radiolucency rate at 5-7 months also was significantly higher in ankles with screws alone than in ankles with plates. In the biomechanical evaluation using full tibia and fibula sawbones, maximum compression force within the syndesmosis was measured using the ISCAN sensor (TekScan). The addition of the fibular plate allowed significantly higher compression than the use of screws alone.

Adult↗