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Horng-Chaung Hsu

Publications and source records attributed to Horng-Chaung Hsu.

13 recordsLinked to original sources
PubMed2006

Nerve sheath ganglion of the tibial nerve presenting as a Baker's cyst: a case report.

Nerve sheath ganglion is a relatively rare clinical entity commonly found in the peroneal nerve in the lower limb or the ulnar nerve in the upper extremity. It is rarely found in the tibial nerve. The occurrence of a nerve sheath ganglion in a patient's tibial nerve has been identified. The initial presentation of the tumor mass has been very similar to that of a Baker's cyst, namely a soft undulating popliteal mass. Yet, the case also presented symptoms and signs of tibial nerve compressive neuropathy. We present here a rare case of nerve sheath ganglion of the tibial nerve. Clinical courses of the patient were reviewed, and relevant issues were discussed with a thorough literature review.

Adrenal Cortex Hormones↗
PubMed2006

Influence of functional bracing on the kinetics of anterior cruciate ligament-injured knees during level walking.

BACKGROUND: Use of functional knee braces has been suggested to provide protection and to improve kinetic performance of the knee in anterior cruciate ligament-injured patients. However, the efficacy of knee bracing in achieving these goals is still controversial. The purpose of this study was to examine the immediate effects of functional bracing on the three-dimensional kinetics of the knee in individuals with anterior cruciate ligament injuries during level walking. METHODS: Fifteen anterior cruciate ligament-deficient and 15 anterior cruciate ligament-reconstructed subjects were each fitted with a DonJoy Goldpoint brace and walked at a self-selected pace, first without and then with the brace. Kinematic and kinetic data were measured and three-dimensional joint moments and angular impulses at the knee were calculated and compared between bracing conditions and between limbs. FINDINGS: Functional knee bracing did not significantly affect the kinetics of the unaffected knees for either group. Bracing significantly increased the peak abductor moments in anterior cruciate ligament-deficient knees and reduced the bilateral kinetic asymmetry in the coronal plane. For the anterior cruciate ligament-reconstructed group, bracing increased peak moments and impulses of the abductors and extensors. It also reduced bilateral kinetic asymmetry in the sagittal and coronal planes. INTERPRETATION: Effects of the knee brace were apparent in the coronal plane for both anterior cruciate ligament-deficient and anterior cruciate ligament-reconstructed patients, and in the sagittal plane for anterior cruciate ligament-reconstructed patients. Functional bracing can be recommended for anterior cruciate ligament-reconstructed patients to assist in achieving better bilateral kinetic symmetry during gait. For anterior cruciate ligament-deficient patients, apart from bracing, additional emphasis on the rehabilitative training for better kinetic knee performance in the sagittal plane is needed.

Adult↗
PubMed2006

Comparison between F-18-FDG positron emission tomography and histology for the assessment of tumor necrosis rates in primary osteosarcoma.

BACKGROUND: The purpose of this prospective study was to identify if F-18-fluorodeoxy-D-glucose positron emission tomography (F-18-FDG PET) was a reliable noninvasive surrogate of histologic response in determining the efficacy of neoadjuvant chemotherapy before surgical resection in primary osteosarcoma. METHODS: Between January 2003 and December 2003, 10 patients with primary osteosarcomas were examined using F-18-FDG PET before neoadjuvant chemotherapy and surgery. The mean age at the time of first intervention was 19 years (range, 4-47 years). Positive prognostic significance was defined as more than 90% tumor necrosis response following neoadjuvant chemotherapy. The parameters of FDG uptake were correlated with histologic findings. The intraclass correlation coefficient was used to validate the tumor necrosis rates determined by PET and histology. RESULTS: The tumor necrosis rate determined by PET was comparable with that determined histologically. The mean standardized uptake value before and following neoadjuvant chemotherapy were 8.2 and 4.4, respectively. The average tumor necrosis rate determined by PET was 22%. However, the mean tumor necrosis rate determined histologically was 54.5%. According to the intraclass correlation coefficient models, the intraclass correlation coefficient equaled O. The relationship of tumor necrosis rates determined by F-18-FDG PET and histology seems to be statistically insignificant. CONCLUSION: In this preliminary study, FDG PET did not seem to be a promising tool for evaluating the response of primary osteosarcoma to neoadjuvant chemotherapy.

Adolescent↗
PubMed2006

Mucoid degeneration of the anterior cruciate ligament.

We report 2 cases of mucoid degeneration of the anterior cruciate ligament (ACL). Mucoid degeneration of the ACL is a very rare cause of knee pain. The first patient presented with extension block of the knee, and the second patient had simple knee pain. Both patients did not have obvious trauma history or clinical instability of the knee. After arthroscopic debridement of the lesion, both patients regained full range of motion of the knee and were pain-free at follow-up. Mucoid degeneration of the ACL is suspected when an apparently thickened and ill-defined ligament with increased signal intensity on all sequences in magnetic resonance imaging is identified in a patient with physically intact ligament and no obvious trauma history. Arthroscopic debridement of the mucoid degeneration of the ACL was safe and effective in these 2 patients.

Anterior Cruciate Ligament↗
PubMed2005

Intrapelvic migration of a Kirschner wire.

Intrapelvic migration of a Kirschner wire, used in the treatment of hip fracture, is rare. We report a case of intrapelvic migration of a Kirschner wire 10 years after its placement. Even though the patient was asymptomatic, we proceeded to remove the migrated wire using laparoscopic techniques. Given the increasing number of hip operations being performed, and given that intrapelvic foreign bodies can result in serious or fatal complications, it is important to keep this problem in mind in patients who have had previous hip surgery.

Aged↗
PubMed2005

A modified cell culture method for autologous chondrocyte transplantation.

Autologous chondrocyte transplantation (ACT) is a promising method to treat chondral and osteochondral defects. This study introduced a modified method for cell culture in ACT. Porcine chondrocytes were cultured for 3 weeks under low hydrostatic pressure at 250 Pa. The results showed that the dry weight of the cartilage-like membrane in the loading group was 3.0 times more than the control group (no loading) (p < 0.01), and cell numbers were significantly increased by 3.1 times (p < 0.01) after a 3-week culture. Compared with the fresh tissue sample, the mRNA expression of collagen II was not statistically different and the mRNA of aggrecan was only slightly decreased by 19%. These data suggest that the hydrostatic pressure at this level significantly increased the cell numbers and biosynthesis of cultured chondrocytes.

Animals↗
PubMed2004

Tensile forces attenuate estrogen-stimulated collagen synthesis in the ACL.

The purpose of this study was to examine whether mechanical tensile forces affect estrogen regulation of collagen synthesis of anterior cruciate ligament fibroblasts at the mRNA level. Estrogen was studied at three physiologic levels, 10(-11), 10(-10), and 10(-9)M. The results revealed that estrogen alone stimulated Type I and III collagen synthesis at the mRNA level, and application of mechanical force decreased the expression of collagen Type I and III genes at all tested estrogen levels. These findings suggest that estrogen may directly regulate ligament structure and function by alteration of Type I and III collagen synthesis. This regulation is dependent on mechanical loading.

Animals↗
PubMed2004

The combined regulation of estrogen and cyclic tension on fibroblast biosynthesis derived from anterior cruciate ligament.

Female athletes are two to eight times more likely to suffer a knee or ankle ligament injury than male athletes, and sex hormones have been considered to play an important role in the injury. Because ligaments are always under mechanical loading during sports, mechanical force is also a critical factor in ligament injuries. In this study, the effects of estrogen and mechanical loading on the gene expression of three major components of ligament--collagen type I, type III, and biglycan--in primary cultured porcine anterior cruciate ligament (ACL) fibroblasts were investigated individually and collectively using reverse transcript-polymerase chain reaction (RT-PCR). The results revealed that cyclic tensile loading alone increased the messenger RNA expression of collagen I but did not affect that of collagen III and biglycan, and estrogen alone increased the gene expression of collagen I and III but not of biglycan. However, combined administration of estrogen and cyclic loading inhibited the mRNA expression of all the three genes. These results suggested that the inhibition of the gene expression of major extracellular matrix component molecules caused by the combined effects of estrogen and mechanical loading, unique to females, might be responsible for the increased incidence of ligaments injury in female athletes.

Animals↗
PubMed2003

Correlation between rotator cuff tear and glenohumeral degeneration.

We studied the occurrence and correlation between a rotator cuff tear and glenohumeral degeneration. 44 cadaveric shoulders (22 right) were obtained from 32 subjects (18 females), mean age 73 (62-86) years and without a history of systemic diseases. Rotator cuffs were exposed and tear size (14 shoulders) was measured after removal of soft tissue and deltoid. Articular cartilage damage of the glenoid and humeral head was recorded by photography. A grading system of 1 (intact), 2 (mild) and 3 (severe) was used to determine the severity of cartilage damage. The area of articular cartilage damage was calculated using the Sonic Digitizer Analyzing System. The area of articular cartilage damage to the glenoid and the humeral head in the rotator cuff tear group was 32% and 36%, respectively. It was greater than that in the groups without a tear, which was 6% in the glenoid and 7% in the humeral head. However, it was not correlated with the size of the tear. Most of the articular cartilage damage in massive and large rotator cuff tears was located in the anterior-inferior portion of the glenoid and in the posterior portion of the humeral head. The articular cartilage damage area of the glenoid was correlated with that of the humeral head. In conclusion, the area of glenohumeral degeneration was greater in the rotator cuff tear group and was located in a specific site.

Aged↗
PubMed2003

A radiological study after anterior cruciate ligament reconstruction.

BACKGROUND: Disruption of the anterior cruciate ligament is a common injury, often resulting in functional instability. Currently, arthroscopic anterior cruciate ligament (ACL) reconstruction using the central third bone-patellar tendon-bone graft is a common surgical procedure. The purpose of this study was to evaluate the postoperative structural remodeling in the ligament following ACL reconstruction over time by X-ray and magnetic resonance imaging (MRI). METHODS: We performed arthroscopic ACL reconstruction with central third bone-patellar tendon-bone autograft for 27 patients (14 males, 13 females, mean 27.2 years old) between October 1995 and January 1999. All patients were examined post-operatively at 3, 6, 12, and 18 months by X-ray to evaluate the sequential change of the tibia bone tunnel and by MRI to monitor the sequential signal changes in the recipient and donor sites. RESULTS: The MRI showed an increased signal at the patellar tendon (donor site) at 3 and 6 months and decreased signal after 1 year. The signal of ACL graft from MRI remained increased after operation. On AP, lateral view of X-ray, the diameter at the joint site of the tunnel was larger than at the bone plug site. Pearson correlation method revealed that the diameter of the bone tunnel expanding at the joint site was statistically greater than that at the bone plug site (p < 0.05). The difference between the bone tunnel diameter at the bone plug site and the joint site was not statistically correlated with the distance between them (by linear regression method, p = 0.77). CONCLUSIONS: We concluded that the windshield wiper effect could not be the only factor inducing the enlargement of the bone tunnel, based on our results. The signal change of patellar tendon was more obvious than that of the bone-patellar tendon-bone graft.

Adolescent↗
PubMed2003

Extraskeletal mesenchymal chondrosarcoma.

Extraskeletal mesenchymal chondrosarcoma is a rare malignancy. It is characteriged by a bimorphic histologic pattern, with a mesenchymal tissue mixed with malignant hyaline cartilage. It also has high incidence of local recurrence and distant metastasis. All cases have been reported fatal associated with this tumor in spite of complete surgical excision. A 35-year-old female presented with a palpable mass about 5 x 3 x 2.5 cm3 in size over her left forearm and was reported to be an extraskeletal mesenchymal chondrosarcoma. Marginal resection followed by regional radiotherapy was done. No local recurrence or distant metastasis was found two years after surgery. Thorough physical examination, series radiographic studies, and multiple sites of tumor biopsies before radical resection of the tumor may decrease the misdiagnostic rate for extraskeletal mesenchymal chondrosarcoma. Appropriate tumor treatment, close patient follow-up and timely treatment for local recurrence or distant metastasis may increase the survival rate.

Adult↗
PubMed2002

An in vitro study of glenohumeral performance after suprascapular nerve entrapment.

PURPOSE: The functional performance of athletes with suprascapular nerve entrapment remains unaddressed biomechanically. The purpose of this study was to investigate the glenohumeral joint kinematics, stability, and characteristics of joint contact. METHODS: The investigation used an in vitro model simulating muscle palsy due to the suprascapular nerve entrapment. The experiment was performed in three clinically relevant positions: inferior, one by sulcus test; posterior, one with 90 degrees flexion and maximal internal rotation; and anterior, one with 90 degrees abduction and 90 degrees external rotation (which is critically involved in several sports activities). RESULTS: Simulated palsy due to suprascapular nerve entrapment had effects on glenohumeral joint stability and contact characteristics. Changes in the humeral head displacement and the glenohumeral joint contact characteristics were the most significant in the anterior direction when the arm in 90 degrees abduction and 90 degrees external rotation. CONCLUSION: Glenohumeral function is affected by muscle weakness at the position that is critical in sports activities. Because the infraspinatus supplies 90% of the external rotation power of the shoulder and the supraspinatus stabilizes the humeral head in the glenoid during elevation, residual weakness due to suprascapular nerve entrapment may preclude a safe return to athletics.

Aged↗