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Biomedical subjects

Hugh Herr

Publications and source records attributed to Hugh Herr.

5 recordsLinked to original sources

A clinical comparison of variable-damping and mechanically passive prosthetic knee devices.

OBJECTIVE: Although variable-damping knee prostheses offer some improvements over mechanically passive prostheses to transfemoral amputees, there is insufficient evidence that such prostheses provide advantages at self-selected walking speeds. In this investigation, we address this question by comparing two variable-damping knees, the hydraulic-based Otto Bock C-leg and the magnetorheological-based Ossur Rheo, with the mechanically passive, hydraulic-based Mauch SNS. DESIGN: For each prosthesis, metabolic data were collected on eight unilateral amputees walking at self-selected speeds across an indoor track. Furthermore, kinetic, kinematic, and electromyographic data were collected while walking at self-selected speeds across a 10-m walkway in a laboratory. RESULTS: When using the Rheo, metabolic rate decreases by 5% compared with the Mauch and by 3% compared with the C-leg. Furthermore, for the C-leg and Rheo knee devices, we observe biomechanical advantages over the mechanically passive Mauch. These advantages include an enhanced smoothness of gait, a decrease in hip work production, a lower peak hip flexion moment at terminal stance, and a reduction in peak hip power generation at toe-off. CONCLUSION: The results of this study indicate that variable-damping knee prostheses offer advantages over mechanically passive designs for unilateral transfemoral amputees walking at self-selected ambulatory speeds, and the results further suggest that a magnetorheological-based system may have advantages over hydraulic-based designs.

Adult↗

An apparatus for characterization and control of isolated muscle.

An apparatus for characterization and control of muscle tissue is presented. The apparatus is capable of providing generalized mechanical boundary conditions to muscle tissue, as well as implementing real-time feedback control via electrical stimulation. The system is intended to serve as an experimental platform for implementing a wide variety of muscle control and identification studies that will serve as fundamental investigations of muscle mechanics, energetics, functional electrical stimulation, and fatigue. In one illustration of the capabilities of the apparatus, pilot experimental results of muscle workloops against a finite-admittance passive load are presented, illustrating how richer boundary conditions may reveal interesting muscle behavior.

Animals↗

A swimming robot actuated by living muscle tissue.

Biomechatronics is the integration of biological components with artificial devices, in which the biological component confers a significant functional capability to the system, and the artificial component provides specific cellular and tissue interfaces that promote the maintenance and functional adaptation of the biological component. Based upon functional performance, muscle is potentially an excellent mechanical actuator, but the larger challenge of developing muscle-actuated, biomechatronic devices poses many scientific and engineering challenges. As a demonstratory proof of concept, we designed, built, and characterized a swimming robot actuated by two explanted frog semitendinosus muscles and controlled by an embedded microcontroller. Using open loop stimulation protocols, the robot performed basic swimming maneuvers such as starting, stopping, turning (turning radius ~400 mm) and straight-line swimming (max speed >1/3 body lengths/second). A broad spectrum antibiotic/antimycotic ringer solution surrounded the muscle actuators for long term maintenance, ex vivo. The robot swam for a total of 4 hours over a 42 hour lifespan (10% duty cycle) before its velocity degraded below 75% of its maximum. The development of functional biomechatronic prototypes with integrated musculoskeletal tissues is the first critical step toward the long term objective of controllable, adaptive and robust biomechatronic robots and prostheses.

Journal Article↗

Adaptive control of a variable-impedance ankle-foot orthosis to assist drop-foot gait.

An active ankle-foot orthoses (AAFO) is presented where the impedance of the orthotic joint is modulated throughout the walking cycle to treat drop-foot gait. During controlled plantar flexion, a biomimetic torsional spring control is applied where orthotic joint stiffness is actively adjusted to minimize forefoot collisions with the ground. Throughout late stance, joint impedance is minimized so as not to impede powered plantar flexion movements, and during the swing phase, a torsional spring-damper control lifts the foot to provide toe clearance. To assess the clinical effects of variable-impedance control, kinetic and kinematic gait data were collected on two drop-foot participants wearing the AAFO. For each participant, zero, constant, and variable impedance control strategies were evaluated and the results were compared to the mechanics of three age, weight, and height matched normals. We find that actively adjusting joint impedance reduces the occurrence of slap foot allows greater powered plantar flexion and provides for less kinematic difference during swing when compared to normals. These results indicate that a variable-impedance orthosis may have certain clinical benefits for the treatment of drop-foot gait compared to conventional ankle-foot orthoses having zero or constant stiffness joint behaviors.

Aged↗

Swing-leg retraction: a simple control model for stable running.

In running, the spring-like axial behavior of stance limbs is a well-known and remarkably general feature. Here we consider how the rotational behavior of limbs affects running stability. It is commonly observed that running animals retract their limbs just prior to ground contact, moving each foot rearward towards the ground. In this study, we employ a conservative spring-mass model to test the effects of swing-leg retraction on running stability. A feed-forward control scheme is applied where the swing-leg is retracted at constant angular velocity throughout the second half of the swing phase. The control scheme allows the spring-mass system to automatically adapt the angle of attack in response to disturbances in forward speed and stance-limb stiffness. Using a return map to investigate system stability, we propose an optimal swing-leg retraction model for the stabilization of flight phase apex height. The results of this study indicate that swing-leg retraction significantly improves the stability of spring-mass running, suggesting that swing-phase limb dynamics may play an important role in the stabilization of running animals.

Animals↗