PubMed Health⌕ Search

Biomedical subjects

I A Gusev

Publications and source records attributed to I A Gusev.

6 recordsLinked to original sources
PubMed2004

[Case of chronic radiation sickness with subsequent leukemia in track driver subjected to long-external gamma-irradiation (cesium-137)].

The article deals with consequences seen in track driver after prolonged exposure to radiation caused by "lost" gamma-source (cesium-137) that long remained in receptacle of the vehicle's left door. Radiation dose averaged 8 Gy. The authors presented clinical manifestations, changes in peripheral blood and bone marrow, cytogenetic data by progression of radiation hemopoiesis hypoplasy to myelodysplastic syndrome and to acute leukaemia.

Adult↗
PubMed1997

[Spondyloarthropathies and HLA-B27 subtypes in the populations of the Russian North].

The aim of the study was to investigate the role of HLA-B27 subtypes in development of ankylosing spondylitis and other seronegative spondylarthropathies. Using oligotyping techniques we studied native DNA of 219 HLA-B27 positive natives: 88 Chukotka residents and 131 Mordovians (Russian Ugro-Finnish population). Only subtypes HLA-B*2705 and B*2702 were revealed. A dominant subtype of HLA-B27 among the natives was HLA-B*2705: 99% among residents of Chukotka and 86% among Mordovians. It was established that among spondylarthropathic patients the frequency of B*2705 does not differ from its incidence in the studied populations. The data support the suggestion that several B27 subtypes and common genetic determinant of B27 gene may be involved in pathogenesis of spondylarthropathy.

Alleles↗
PubMed1996

Internal exposure of the staff involved in the cleanup after the accident at the Chernobyl nuclear power plant in 1986.

This article presents the results of our work from 1987 to 1994 on the reconstruction of internal exposure of the witnesses to the Chernobyl accident with respect to inhalation of airborne particles of nuclear fuel. Our results eliminate the hypothesis that inhalation intake of radioactive aerosols was a considerable pathway of exposure for staff at the Chernobyl nuclear power plant. It would conceivably lead to a nonuniform dose distribution in the body. Under that condition, actual equivalent doses in some organs, e.g., in lungs and in the wall of the lower large intestine are much higher than the actual effective dose. Therefore it is impossible to correctly assess the health risk for certain cohorts of the Chernobyl accident witnesses if the inhalation pathway is neglected. In that case not only the actual effective dose, but the actual equivalent doses too play a role in radiological measurement, when evaluating the hazard for less-exposed accident witnesses. That conclusion is of great importance to radiation protection policy, the planning of epidemiological studies and the carrying out of medical remedial actions for the different cohorts of accident witnesses. The findings should be taken into consideration in planning protective measures and in assessing health effects following the Chernobyl accident.

Air Pollutants, Radioactive↗
PubMed1990

[An assessment of the contribution of internal irradiation to the early manifestations of acute radiation sickness in the victims of the accident at the Chernobyl Atomic Electric Power Station].

Materials of the investigation of victims of the accident at the Chernobyl Nuclear Power Plant were used for the estimation of a contribution of exposure with incorporated radionuclides to a course of acute radiation syndrome thyroid and pulmonary lesions. Attention was granted to patients who died as a result of accidental exposure. Dose values of thyroid, pulmonary and total body exposure were given. The severity of the affection of the bronchopulmonary and hypophysial-thyroid systems was assessed. The results of cytogenetic investigations to estimate absorbed doses were represented for some persons. Internal exposure was shown to make a considerable effect on the development of acute radiation syndrome in two persons only, internal whole-body exposure doses being compatible with a total exposure dose.

Accidents↗