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Biomedical subjects

I A Krasil'nikov

Publications and source records attributed to I A Krasil'nikov.

10 recordsLinked to original sources
PubMed1990

[The general characteristics of the epidemic process and of the circulating streptococcal strains during an upsurge in scarlatina morbidity in Leningrad].

The dynamics of scarlet fever morbidity in Leningrad for many years was studied and the absence of any effect produced by the existing system of preventive measures against this disease for the last 30 years was shown. On the basis of epidemiological and bacteriological data the authors came to the conclusion on the unity of the epidemic process of scarlet fever in the whole city and the relatively autonomous character of the process in individual districts. The necessity of the realization of epidemiological surveillance on streptococcal infection, with special emphasis on the multilevel social structure of the city and the wide use of the bacteriological diagnosis of streptococcal diseases, is substantiated.

Disease Outbreaks↗
PubMed1990

[The OF characteristics of streptococci group A and immunity to streptococcal infection based on the results of OF and anti-OF tests].

The influence of the OF activity of group A streptococci on their specific pathogenic properties has been shown, which is manifested by increased virulence of these streptococci for children of younger age groups and by a two times higher isolation rate of OF+ strains in tonsillitis than in scarlet fever. The possibility of the indirect evaluation of the content of anti-M-antibodies by the results of the anti-OF test has been revealed, which permits using this test instead of the bactericidal test, more complicated, in the study of immunity to infection induced by group A OF+ streptococci. Among the main methods of laboratory support of epidemiological surveillance on streptococcal infection, the introduction of the highly discriminating OF typing and the anti-OF test into practical use is recommended.

Antibodies, Bacterial↗
PubMed1985

[Typing of Streptococcus group A isolated from patients and healthy persons].

The typing of 80% of 381 streptococcal strains, group A, under study was accomplished with a set of diagnostic anti-T sera obtained from the Sevak Institute (Czechoslovakia). None of the T-types could be related with certainty to the localization of the infective agent in the human body (the pharynx, the skin). Different T-types were shown to circulate in definite regions of the USSR. To enhance the differentiating capacity of T-typing, the enzymatic (lipoproteinase and NADase) activity of the strains was determined, thus permitting the subdivision of the T-types into still smaller groups. The typing of OF+ strains of unknown M-specificity could be carried out by means of the blood sera of healthy persons, containing antibodies to streptococcal lipoproteinase. The conclusion on the expediency of using the determination of lipoproteinase and NADase as an additional marker in the typing of group A streptococci was made.

Adult↗