[Diagnosis of the resistant ovary syndrome].
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Biomedical subjects
Publications and source records attributed to I A Pakhomova.
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Correlation between 17 beta-estradiol blood content and the excretion of estrogens was studied during 19 cycles in 10 women with amenorrhea treated with pergonal-500. A high degree of correlation between two lines of values has been observed (r = 0.89 +/- 0.03). It is concluded that both methods are equally informative in the evaluation of pergonal therapeutic effect.
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Luteinizing hormone (LH), folliculostimulating hormone (FSH) and progesterone were studied by the radioimmunoassay in a group of 10 women throughout a normal menstrual cycle. The LH and the FSH peak occurs at the middle of the cycle. At the early follicular phase the FSH level was higher than that of the LH. During the follicular and the lutein phases the plasma progesterone level was 0.65 +/- 0.12 ng/ml and 12.4 +/- 2.3 ng/ml, respectively. The laboratory criteria of the normal ovular cycle are: a) a mid-cycle LH peak; b) plasma progesterone level at the lutein phase were 10-15 times greater than at the follicular one; c) progesterone peak at the mid-lutein phase; d) the duration of the lutein phase of 12-15 days.