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Biomedical subjects

I A Pakulin

Publications and source records attributed to I A Pakulin.

15 recordsLinked to original sources
PubMed1992

[Comparison of the informative value of the dipyridamole test, transesophageal electrostimulation and exercise tests in the diagnosis of coronary heart disease].

The informative value of dipyridamole test, transesophageal cardiac pacing, bicycle ergometer and treadmill exercise tests were compared in 65 patients suspected for coronary heart disease and Functional Classes I-III angina pectoris. The sensitivity, specificity, positive and negative predictive values of the techniques alone and in various combinations were evaluated. The incoincidence of results from exercise tests was ascertained to be 40-48%. The significance of diagnosis increased with combined functional examination and reached the maximum when all the four tests were performed. The use of the sensitivity, specificity, and predictive value of the techniques in assessing the individual test results allows the optimal scope of studies to be determined on an individual basis in order to make or exclude the diagnosis of coronary heart disease.

Adult↗
PubMed1991

[Comparing the informative value of bicycle ergometry and treadmill tests in the evaluation of the coronary reserve].

The diagnostic potentialities of bicycle ergometry (BEM) and treadmill test were comparatively analysed in 57 males aged 37-64 years who were examined to detect coronary heart disease. In 34 cases, the results of BEM and treadmill test were consistent, of them 13 were positive, 15, negative, 3 intermediate, and 3 inadequate. With positive results, the treadmill test was more reliable than BEM in revealing the criteria for ischemia from statistically significantly more pronounced ST-segment depression at a lower threshold heart rate. Inconsistency of the BEM and treadmill test results was found in 23 cases. In 14 of 18 patients who had indefinite BEM results, the treadmill test allowed one to make a definite conclusive diagnosis, showing 6 positive and 8 negative results. This is accounted for by lower cases when the treadmill test was discontinued due to a hypertensive reaction of blood pressure or fatigue. The study indicated that the treadmill test was more sensitive and better tolerated than BEM.

Adult↗
PubMed1989

[State of the ventilatory function of the lungs in heavy smokers].

Computed spirography, He/O test and capnography evaluation of external respiration has been carried out for 52 subjects. Of these 27 were nonsmokers, 25 smoked but had no history of respiratory diseases. The integral criteria of external respiration obstruction (MOCmax, MOC50, MOC75) proved inadequate diagnostic tool for early detection of ventilatory alterations in smokers who are at risk to develop chronic nonspecific pulmonary diseases. Pharmacological tests, He/O investigation and capnography did reveal defects in small bronchi permeability in all the smokers. Problems of pathogenesis of obstructive affections of distal regions of the bronchial tree are under consideration.

Humans↗
PubMed1984

[Detection of latent hemodynamic disorders of the lesser circulation in patients with chronic obstructive bronchitis and bronchial asthma].

Thirty-three patients with infectious allergic bronchial asthma and chronic obstructive bronchitis and 47 normal subjects were examined with the aid of a complex of bloodless research methods for the pulmonary circulation and central hemodynamics under graded physical exercise of minor power. Investigation at rest did not disclose any hemodynamic disorders in the greater and pulmonary circulation. Application of bicycle ergometry to patients with chronic obstructive bronchitis and bronchial asthma in a stage of remission made it possible to reveal latent hemodynamic disorders of the pulmonary circulation that manifested by long-term elevation of the pressure in the pulmonary artery and pulmonary vascular resistance, restitution of the central hemodynamics according to the hyperkinetic type. The use of the generally accepted formulas for calculating the proper magnitudes of the ejection period and mechanical systole with the heart rate exceeding 90 per minute resulted in overdiagnosis of the overload of the right ventricle. The authors offer the regression equations for calculating these parameters during tachycardia.

Adult↗
PubMed1980

[Evaluation of the hemodynamic reactions of the greater and lesser circulations in performing functional load tests].

A complex of bloodless examination methods (tetrapolar rheography, rheopulmonography, cinecardiography) was used in studying hemodynamics of systemic and pulmonary circulation at rest and after dosed exercises performed in a supine position. Forty-seven healthy persons were examined at rest and 1, 3, 6, 10, and 15 minutes after cessation of the exercise tolerance test. After the test the values of hemodynamics return to the initial levels on the 6th--10th min of rest. It is shown that the suggested complex of examination methods may be used for disclosing latent disorders of adaptation to physical exercise and for control over the efficacy of treatment of patients with diseases of the organs of circulation and respiration.

Adult↗