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Biomedical subjects

I A Shivitz

Publications and source records attributed to I A Shivitz.

6 recordsLinked to original sources

Bilateral keloid-like myofibroblastic proliferations of the cornea in children.

Two 6-month-old white boys developed localized multifocal white nodules of the anterior corneal stroma without evidence of antecedent trauma, inflammatory disease, or familial occurrence. The first patient had bilateral lesions initially; the second patient initially had unilateral involvement followed by a corneal nodule in the second eye at 11 years of age. Light and electron microscopic studies of the lesions in both patients were similar and disclosed stromal nodules composed of proliferating myofibroblasts, activated fibroblasts, and haphazardly arranged fascicles of collagen. Immunohistochemical studies revealed that the spindle cells within the nodules expressed immunoreactivity for vimentin and alpha-smooth muscle actin. Management options for these slowly progressive corneal lesions include lamellar versus penetrating keratoplasty and topical corticosteroids.

Child, Preschool↗

Corneal sensitivity after radial keratotomy.

Corneal sensitivity was tested in 76 eyes of 40 patients who underwent radial keratotomy for the correction of myopia, and radial keratotomy plus transverse incisions for the correction of myopia and astigmatism. There was a decrease in corneal sensitivity in 30.9 and 9.5% of patients undergoing radial keratotomy after 6 and 12 months, respectively. Approximately 70% of patients in this group had a recovery of lost sensitivity after 6 months. There was a similar decrease in sensitivity in 79.4 and 47.0% of patients undergoing radial keratotomy with the addition of transverse incisions for astigmatism at 6 and 12 months, respectively. The recovery rate in this group was 40.7%. The most significant loss of corneal sensation was in the areas central to the transverse incisions. The depth of the transverse incision, as well as the preoperative astigmatism, appeared to be factors in the loss of corneal sensation as well as in the recovery of the corneal sensitivity. There were no complications noted in this study as a result of decreased corneal sensitivity.

Adult↗

Contact lenses in the treatment of patients with overcorrected radial keratotomy.

Thirty-two eyes of 28 patients who underwent radial keratotomy had a hyperopic overcorrection after the surgical procedure. Anisometropia, with associated aniseikonia and depth perception problems were present in many of these patients. The patients were subsequently fit with contact lenses. Conventional methods of fitting contact lenses in these patients were unsuccessful. A trial lens technique is used with the initial lens having a base curve equal to the preoperative keratometry measurements and the power equal to the preoperative spherical equivalent. Superficial neovascularization developed within the radial incisions in 33% of the eyes fitted with soft contact lenses. Gas permeable contact lenses offered patients the best-corrected visual acuity as well as minimal complications. In addition, the anisometropia was minimized, and fluctuating vision was eliminated in cases in which it was a problem.

Contact Lenses↗

Bilateral simultaneous Pseudomonas keratitis with myopic extended-wear contact lenses.

Bacterial keratitis is reported more frequently in the literature with the use of extended-wear contact lenses. This report describes a case of bilateral simultaneous pseudomonas keratitis in an elderly patient wearing extended-wear contact lenses for correction of myopia. The lenses were not properly disinfected prior to the development of the corneal ulcers. When bacterial keratitis is suspected with the use of extended-wear contact lenses, prompt diagnosis and treatment are necessary. Appropriate microbiologic testing of the contact lenses, lens cases, and lens solutions should also be undertaken.

Aged↗

Delayed keratitis after radial keratotomy.

A number of serious complications have been reported after radial keratotomy. In this article, we describe three episodes in two cases of delayed keratitis after radial keratotomy. The keratitis was noted nine months, 35 months, and 40 months after radial keratotomy. Delayed wound healing and epithelial inclusion cysts are likely causes. To our knowledge, this is the first report in the literature of delayed keratitis occurring as a late complication after radial keratotomy.

Adult↗