[Cancer metastasis to the appendix vermiformis in combination with phlegmonous appendisitis].
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Biomedical subjects
Publications and source records attributed to I A Smotrova.
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Anomalous DNA synthesis was seen in the stomach mucosa of mice with experimental stomach ulcer during different phases of the ulcerous process, using histoautoradiography. At the early stage of ulcer formation a decrease in the label index (LI) is seen. Formation of the ulcer, morphologically similar to the shronic one, is accompanied by growth of the number of DNA-synthesizing cells in its margins. Over a period of ulcer healing proliferative activity of epithelium decreases approximately to an initial level. Histoautoradiographic studies of bioptates of the stomach mucosa obtained under spot gastroscopy in patients suffering from the ulcerous disease allowed to reveal intensifying proliferative activity of epithelium in the ulcer margins. Similar changes in LI were found in gastritis, followed by the gland affection, and in atrophic gastritis.
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The efficacy of the treatment with an agluten diet of celiac disease of the adults was studied in 45 patients over time, the observation periods ranging from 6 months to 6 years. The results were assessed from the patients' clinical examination that included study of absorption function of the small intestine (daily mass and fat loss with feces, absorption of D-xylose), determination of hemoglobin, total protein in blood serum, and morphological study of the jejunum mucosa obtained on aspiration enterobiopsy. Analysis of the data has shown that the patients who strictly observed the agluten diet noted a clinical remission with a tendency towards morphological improvement of the structure of small intestinal mucosa. No such an improvement was recorded in patients given gluten on a periodic basis.