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Biomedical subjects

I A Sytinskiĭ

Publications and source records attributed to I A Sytinskiĭ.

At least 19 recordsLinked to original sources

[Clinical picture and changes in the activity of several cerebrospinal fluid enzymes in stroke].

Having studied the clinical picture and changes in the activity of various enzymes in the cerebrospinal fluid (CSF) in 140 patients with cerebral strokes, the authors showed a diagnostic and prognostic value of determining the activity of LDH and GGTP in the CSF. The activity of these enzymes increased in hemorrhagic stroke and in cases of unfavourable outcome. Their activity was lower in ischemic stroke and in cases of a favourable course of the disease.

Adult↗

[Activity of gamma-glutamyltranspeptidase in spinal fluid in diseases of the nervous system].

Gamma-Glutamyltranspeptase (gamma-GTP) activity was studied in cerebrospinal fluid (CSF) of 131 patients with varying diseases of the nervous system. The enzyme activity proved to be drastically high in patients with cerebral stroke, cerebral or spinal tumors, disseminated encephalomyelitis, and depended on the disease severity, its activity and connection of the pathologic foci with the liquor paths. The diagnostic and prognostic importance of gamma-GTP evaluation in CSF is shown.

Arachnoiditis↗

[Adaptive changes in brain metabolism during chronic alcoholic intoxication].

Chronically alcoholized intoxication (1.5--2 months) induces adaptation of cerebral neurones to changing equilibrium states of biochemical processes by altering the activity of enzymes of GABA metabolism, reduction of alanine and aspartate transaminase activity and increase of LDH and succinate dehydrogenase activity. In the cerebellum and cerebral hemispheres during alcohol abstinacy the activity of GABA-T, succinate dehydrogenase and aspartate transaminase was reduced while that of LDH and alanine transaminase was increased. The administration of fusarinic acid (100 mg/kg i. p.) to control animals induced a sharp increase of GAD activity in both structures of the brain. The stimulatory effects of fusarinic acid were not observed when it was administered to animals receiving alcohol chronically. Motor activity or rats was markedly reduced during chronical alcoholism and the first days of alcohol abstinacy (24--48 h), as well as following injection fusarinic acid and homopantothenic acid. The increase of locomotion and the vertical component of motor activity was observed only following one week or one month after alcohol abstinacy.

4-Aminobutyrate Transaminase↗