Biomedical subjects

I Abrashev

Publications and source records attributed to I Abrashev.

At least 19 recordsLinked to original sources

PubMed1990

[The immunomodulating properties of a macro glycopeptide isolated from serum. II. The activation of macrophages and polymorphonuclear cells].

The stimulating properties of three fractions of a glucomacropeptide consisting of different carbohydrate and peptide components were studied. The phagocytic activity of polymorphonuclears was increased on the 24th hour and of macrophages on the 3rd day after application of the preparations to mice. In vitro fraction 3 stimulates the lysozyme activity and the synthesis of proteins and Clq of the macrophages complement. These properties of the cells are collaborated by the established ultrastructural changes. The different composition of the fractions determines their immunostimulating effect.

Adjuvants, Immunologic↗

PubMed1990

[The immunomodulating properties of a glucomacropeptide from whey. I. The stimulation of resistance in mice].

The immunomodulating effect on mice of three products glucomacropeptides obtained from whey with different carbohydrate and peptide components has been studied. After the preliminary application of the preparations at several doses the protective effect in infections with Salmonella typhimurium and Klebsiella pneumoniae increases to different extent. At lower doses fraction 3 increases in vitro the mitogen-induced proliferation of the thymus cells. The phagocytosis of the polymorphonuclear cells on the 24th hour after application of the three preparations is activated. The influence of the structurally different fractions on the immunoprotective effect is discussed.

Adjuvants, Immunologic↗

PubMed1990

[Biochemical research on the neuraminidase of Erysipelothrix rhusiopathiae].

Purified neuraminidase preparation from Erysipelothrix rhusiopathiae is studied biochemically. The main physicochemical characteristics of the enzyme are determined: molecular mass, isoelectric point, electrophoretic mobility, chemical nature, UV spectrum, substrate specificity, etc. The obtained data are compared to those for other bacterial neuraminidases.

Electrophoresis, Polyacrylamide Gel↗

PubMed1988