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Biomedical subjects

I Abubakar

Publications and source records attributed to I Abubakar.

7 recordsLinked to original sources

Medical informatics in medical research - the Severe Malaria in African Children (SMAC) Network's experience.

OBJECTIVES: Computers are widely used for data management in clinical trials in the developed countries, unlike in developing countries. Dependable systems are vital for data management, and medical decision making in clinical research. Monitoring and evaluation of data management is critical. In this paper we describe database structures and procedures of systems used to implement, coordinate, and sustain data management in Africa. We outline major lessons, challenges and successes achieved, and recommendations to improve medical informatics application in biomedical research in sub-Saharan Africa. METHODS: A consortium of experienced research units at five sites in Africa in studying children with disease formed a new clinical trials network, Severe Malaria in African Children. In December 2000, the network introduced an observational study involving these hospital-based sites. After prototyping, relational database management systems were implemented for data entry and verification, data submission and quality assurance monitoring. RESULTS: Between 2000 and 2005, 25,858 patients were enrolled. Failure to meet data submission deadline and data entry errors correlated positively (correlation coefficient, r = 0.82), with more errors occurring when data was submitted late. Data submission lateness correlated inversely with hospital admissions (r = -0.62). CONCLUSIONS: Developing and sustaining dependable DBMS, ongoing modifications to optimize data management is crucial for clinical studies. Monitoring and communication systems are vital in multi-center networks for good data management. Data timeliness is associated with data quality and hospital admissions.

Acute Disease↗

Inter-rater agreement in defining chemical incidents at the National Poisons Information Service, London.

BACKGROUND: National surveillance for chemical incidents is being developed in the UK. It is important to improve the quality of information collected, standardise techniques, and train personnel. OBJECTIVE: To define the extent to which eight National Poison Information Service specialists in poison information agree on the classification of calls received as "chemical incidents" based on the national definition. DESIGN: Blinded, inter-rater reliability measured using the kappa statistic for multiple raters. SETTING: National Poison Information Service and Chemical Incident Response Service, Guy's and St Thomas's NHS Trust, London. PARTICIPANTS: Eight specialists in poison information who are trained and experienced in handling poisons information calls and have been involved in extracting information for surveillance. RESULTS: The overall level of agreement observed was at least 69% greater than expected by chance (kappa statistic). Fire and incidents where chemicals were released within a property had a very good level of agreement with kappa statistic of 83% and 80% respectively. The lowest level of agreement was observed when no one or only one person was exposed to a chemical (33%) and when the chemical was released into the air (48%). CONCLUSION: High levels of agreement were observed. There is a need for more training and improvement in consistency of the data collected by all organisations.

Environmental Exposure↗

Monitoring the uptake of HIV testing among first attendees at GUM clinics in the East of England region.

This study was conducted to determine the extent to which genitourinary medicine clinics in the East of England region are monitoring the uptake of HIV testing. Ninety-four per cent of GUM clinics in the region offer HIV testing to all new patients. The uptake varied around the region, but all clinics are able to monitor uptake and the majority of clinics can audit uptake. The overall regional uptake has already exceeded the target for 2004.

Ambulatory Care Facilities↗

Health centre versus home presumptive diagnosis of malaria in southern Ghana: implications for home-based care policy.

A study was conducted in 1997 to compare the accuracy of presumptive diagnosis of malaria in children aged 1-9 years performed by caretakers of the children to that of health centre staff in 2 ecological zones in southern Ghana. Similar symptoms were reported in the children at home and at the health centre. In the home setting, symptoms were reported the same day that they occurred, 77.6% of the children with a report of fever were febrile (axillary temperature > or = 37.5 degrees C) and 64.7% of the reports of malaria were parasitologically confirmed. In the health centre, the median duration of symptoms before a child was seen was 3 days (range 1-14 days), 58.5% of the children with a report of fever were febrile and 62.6% of the clinically diagnosed cases were parasitologically confirmed. In the 2 settings almost all the infections were due to Plasmodium falciparum. Parasite density was 3 times higher in the health centre cases compared to the home-diagnosed cases. Early and appropriate treatment of malaria detected in children by caretakers may prevent complications that arise as a result of persistence of symptoms and attainment of high parasitaemic levels.

Ambulatory Care↗

Knowledge, attitude and practice of female genital cutting among antenatal patients in Aminu Kano Teaching Hospital, Kano.

BACKGROUND: Despite the widespread practice of FGC, not much attention had been given to it until recently. The attitude of expectant mothers towards it is crucial in sustaining it. OBJECTIVE: To assess knowledge, attitude and practice of female genital cutting among antenatal patients in Aminu Kano Teaching hospital in northern Nigeria METHODS: A cross-sectional study was conducted on 210 antenatal patients seen at Aminu Kano Teaching Hospital from February to March 2003. A structured interviewer-administered questionnaire was used to collect information about socio-demographic characteristics, knowledge, attitude and practice of female genital cutting. RESULTS: Majority (91.4%) of the respondents have heard about FGC. Clitoridectomy and infibulation were known by 36.2% and 5.2% of the respondents respectively. Sixty and 5.2% of respondents knew that HIV/AIDS and Hepatitis could be transmitted by methods used in FGC. Other complications mentioned include sexual dissatisfaction (25.7%) and difficult delivery (8.6%). Furthermore, 16% of respondents wished FGC would continue mainly due to cultural or religious reasons, this opinion was associated with low (20.5%) level of education. Opponents of FGC gave medical complications as their main reason. Prevalence of circumcision was 23.3% and the most common type (36.7%) was clitoridectomy. CONCLUSION: Though awareness about FGC has improved, and attitude towards it appears generally negative, the practice still persists in the north, though at a lower level than the Southeast and Southwest. It was therefore recommended that intensive campaign and health education among mothers and the general public, as well as enforcement of legislation are needed.

Adolescent↗