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I Adam

Publications and source records attributed to I Adam.

79 records · Page 5Linked to original sources
PubMedDate not supplied

Quinine therapy in severe Plasmodium falciparum malaria during pregnancy in Sudan.

A prospective study was carried out in an area of unstable malaria transmission in central Sudan to determine the efficacy and toxicity of quinine in pregnancy. Thirty-three pregnant women with severe Plasmodium falciparum malaria at mean 28.8 weeks gestational age were treated with quinine for 7 days. The mean body temperature on presentation for 3 patients who delivered prematurely was significantly higher than for those who delivered at term (39.2 +/- 0.7 degrees C versus 38.7 +/- 1.3 degrees C). There were no significant difference between the 2 groups in other clinical or biochemical parameters. There were no clinically detectable congenital malformations and no auditory, visual or other neurological deficits in the babies at birth or 6 months later. Quinine may be safe in the treatment of severe falciparum malaria during pregnancy.

Administration, Oral↗
PubMedDate not supplied

Anopheles arabiensis: abundance and insecticide resistance in an irrigated area of eastern Sudan.

The abundance of Anopheles arabiensis and its susceptibility to insecticides was studied in New Halfa, eastern Sudan, from March 1999 to June 2000. Of 4854 females anophelines collected, 4847 (99.9%) were An. arabiensis and 7 (0.1%) An. pharoensis. Female An. arabiensis were breeding throughout the year, with 2 peak densities, during the rainy (158.4 females/room/day and 84.7 larvae/10 dips) and irrigated seasons (136.8 females/room/day and 44.8 larvae/10 dips). The mean biting activity was 28.8 bites/person/ night, found throughout the night, mainly outdoors. Susceptibility of An. arabiensis to insecticides dichloro-diphenyl-trichloroethane (DDT), malathion and fenitrothion was 97.8%, 96.3% and 100% respectively. An. arabiensis is the sole malaria vector in the area and is perennial rather than seasonal.

Agriculture↗
PubMedDate not supplied

Low-dose quinine for treatment of chloroquine-resistant falciparum malaria in Sudanese pregnant women.

Pregnant Sudanese women who presented at a hospital in eastern Sudan with chloroquine-resistant falciparum malaria were randomly allocated to one of two quinine regimens: low-dose (10 mg/kg 2 times/day) (18 patients) or standard (10 mg/kg 3 times/day) (24 patients). Treatment was for 7 days and follow-up for 28 days. Significantly fewer patients in the low-dose group reported vomiting and abdominal pain than the standard regimen group. Hypoglycaemia, preterm labour and recrudescence were slightly but not significantly higher in patients in the standard group than low-dose group. There were no significant differences between the groups in the mean time from admission to remission of fever and parasite clearance. We tentatively advocate the use of quinine 2 times/day to reduce side-effects and improve compliance.

Abdominal Pain↗
PubMedDate not supplied

Quinine for chloroquine-resistant falciparum malaria in pregnant Sudanese women in the first trimester.

A prospective clinical study in eastern Sudan described the efficacy and toxicity of quinine in early pregnancy in mothers with chloroquine-resistant falciparum malaria. Twenty-six pregnant Sudanese women in their first trimester (mean gestational age 8.5 weeks) were given quinine 10 mg/kg 3 times per day for 7 days and followed up every 2 weeks until delivery. One patient aborted (3.8%) and 2 patients (7.7%) experienced threatened abortion but delivered term babies. Recrudescence or re-infection was observed on day 21 in 1 patient. One baby died aged 6 months. There were no detectable congenital malformations, no auditory or visual defects or any other neurological deficits in the remaining infants at birth or 1 year later. Quinine may be safe in the first trimester of pregnancy.

Administration, Oral↗
PubMedDate not supplied

[The Swiss gatekeeper system--a model for improving capacity development and economic effectiveness].

The German as well as the Swiss health care system are facing similar problems. However, in Switzerland different gatekeeper systems to improve the capacity and economic efficiency were successfully tried and tested. The main structures of gatekeeping are the HMO health centres and different GP systems. Central to this idea is the primary care physician functioning as a gatekeeper. He has to control the demands of medical services according to the patient's needs to fulfil integral, comprehensive and economic criteria. Although data processing has not yet been completed yet, first results show clear advantages of the gatekeeper system in respect of the costs and quality of health care compared with the customary Swiss health insurance. Although in Switzerland there are still relatively few persons insured according to the gatekeeper system, it is expected that particularly the family physician systems will expand considerably in the future. Reorganisation and rearrangements of the medical care providers are likely.

Adolescent↗