Nicolae Cajal--60th anniversary.
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History, 20th Century↗
Biomedical subjects
I Aderca
Publications and source records attributed to I Aderca.
Practical aspects of the storage of herpes simplex virus samples.
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Culture Media↗
HBsAg detection by micro-ELISA.
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Counterimmunoelectrophoresis↗
Stability of antimeasles vaccine under the influence of some physical and chemical factors.
A study on the stability of lyophilized and rehydrated measles vaccines under the influence of temperature and light was undertaken. After rehydration there was a considerable decrease in the potency of the vaccine, even when stored at +4 degrees C-- +8 DEGREES C and in the dark. Out of the several drugs tested, the commercially available drug AS was found to have a stabilizing effect on measles vaccine infectivity.
Freeze Drying↗
Persistent measles virus infection in a calf kidney cell line. Note III. Cellular alterations in the selected chronically infected K-2 cell line.
Marked morphological, growth and chromosome alterations pointing to in vitro cellular transformation were made evident in a selected calf kidney cell line (K-2) chronically infected with measles virus. The transformed cell line released infectant virus and had no oncogenic potential for the hamster.
Animals↗
Pitfalls in the sensitivity of HBsAg detection.
A number of 1800 serum samples from apparently healthy subjects were tested by immunodiffusion (ID) and counterimmunoelectrophoresis (CIE) with a view to confirming the presence of HBsAg; results were uncertain in 21% of the cases. The enzyme immunoassay (ELISA kits) used to elucidate these uncertain reactions showed half of them to be negative. About 3% of the remaining sera, HBsAg-positive by ELISA, were positive by ID, but constantly negative by repeated CIE tests. Some possible explanations are suggested and the implications of such pitfalls in the interpretation of sero-epidemiological analyses are discussed.
Counterimmunoelectrophoresis↗