PubMed Health⌕ Search

Biomedical subjects

I Assmann

Publications and source records attributed to I Assmann.

68 records · Page 4Linked to original sources
PubMed1975

[Clinico-pharmacological studies with Nifedipine--a new coronary substance].

On 19 test persons (10 healthy persons, 9 patients with heart diseases) mechanocardiographic and haemodynamic examinations were carried out with the new preparation Nifedipine (05-072) which effects on the coronary vessels. Insignificant positively inotropic effects with invariable heart rate and cardiac output, decreasing heart action and decreased oxygen consumption were found. Arterial blood pressure and peripheral resistance were only slightly diminished. Own results and reports from literature show that the application of Nifedipine in the ischaemic heart disease appears to be successful.

Adult↗
PubMed1975

[Mechanocardiography as a screening method in chronic ischemic heart disease].

On 121 patients with ischaemic heart disease mechanocardiographic examinations were carried out on conditions of rest and partly under conditions of ergometric load and were compared with a group of healthy persons. It was shown that in the patients with ischaemic heart disease there appeared a significant shortening of the ejection time (LVETk), prolongation of the frequency-corrected preejection time (PEPk) as well as of the isovolometric contraction time (ICT and ICTk), an enlargement of the quotient (see article) and reduction of (see article) in rest. Under load the differences between healthy persons and patients with ischaemic heart disease became more clearly with regard to the quotients (see article) as well as (see article) and proved as favourable for the judgment of the cardiomechanics. With the help of the above mentioned mechanocardiographic parameters in connection with the usual diagnostic methods according to our opinion patients with ischaemic heart disease may be diagnosed for the greatest part.

Adult↗
PubMed1975

[Comparison of various screening methods for the diagnosis of chronic ischemic heart disease].

The screening phase of a multifactorial intervention study which is carried out under the direction of the WHO and the aim of which is the influence on mild forms of hypertension, hypercholesterolaemia and slightly disturbed glucose tolerance was supplemented by an electrocardiogram after work under the conditions of screening. The questionnaire contained in the investigation program for the statistical establishment of a typical angina pectoris after work according to Rose and the modified electrocardiographic test after work were tested concerning their evidence in the early recognition of a coronary sclerosis. As reference test served the Watt-step-test recommended by a group of experts of the WHO. An extensive correlation between screening after work and Watt-step-test was found. Questionnaire according to Rose and gradual load, however, had a smaller correspondence. The result of other investigations was that the distribution of the factors of risk does not give any clear reference to the existence of a latent coronary insufficiency.

Angiography↗