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Biomedical subjects

I B Islamova

Publications and source records attributed to I B Islamova.

10 recordsLinked to original sources
PubMed1989

[Plasma alpha/beta lipoprotein coefficient in the diagnosis of progressive muscular dystrophy].

Ten patients with Erb-Roth's progressive muscular dystrophy and 10 ones with Charcot-Marie neural amyotrophy have been examined. The blood plasma lipoproteins have been studied by disk electrophoresis in polyacrylamide gel with Reanal reagents. The studies have revealed different patterns of dyslipidemia and demonstrated the significance of alpha/beta lipoprotein coefficient in the diagnosis of such conditions.

Charcot-Marie-Tooth Disease↗
PubMed1985

[Blood lipid disorders in Becker-Kiner progressive muscular dystrophy].

The article is devoted to one of the rare forms of hereditary neuromuscular diseases--Becker-Kiner progressive muscular dystrophy. Blood lipids were determined in nine patients aged 16 to 45 years with Becker-Kiner progressive muscular dystrophy. Profound disorders of the blood lipid metabolism were established which were expressed in hyperbeta-lipoproteinemia, hypertriglyceridemia, and hypercholesterinemia. The examination of these parameters is useful for objective assessment of the given form of progressive muscular dystrophy.

Adolescent↗
PubMed1985

[Membrane pathology in human myodystrophy].

The authors studied the lipid composition of erythrocytic membranes and levels of pentane (a lipid peroxidation product) in the expired air in patients with Duchenne's myodystrophy. The changes found are discussed in the light of a hypothesis of the generalized membranous defect.

Child↗
PubMed1983

[Plasma lipids of patients with Duchenne's muscular dystrophy at different stages of the disease].

Blood plasma lipids were studied in patients with Duchenne's myodystrophy. The authors examined 40 patients, aged 3-16 years suffering from different stages of Duchenne's muscular dystrophy. Lipids and fractional composition of plasma phospholipids were investigated by thin-layer chromatography on "Silufol" plates; lipoproteins were assessed by the method of high voltage disk electrophoresis in polyacrylamide gel. The changes in plasma lipids were found to be correlated with both the stage of the myodystrophic process and the type of the disease course. The changes included blood plasma lipemia with increased levels of triglycerides, cholesterol and its esters and also a decrease in phospholipid concentrations with the concomitant redistribution of their fractions. A study of the blood plasma lipoprotein spectrum showed a rise in the values of chylomicrons, remnants and alpha-LP. The data obtained are important for objective determination of the disease stage.

Adolescent↗
PubMedDate not supplied

[Clinical role of lipid metabolism indices in the plasma and erythrocytes in progressive muscular dystrophies].

Patterns of lipid metabolism were studied in blood plasma and erythrocytes of patients with various forms of hereditary myopathies (Duchenn disease, Bekker-Kiner disease, Erba-Roth disease, Landuzy-Dejerin disease, Sharko-Mary neural amyotrophy). These diseases were characterized by a number of common patterns: deficiency of phospholipids, specific alterations in properties of lipoproteins and in content of cholesterol. In the Duchenn disease specific alterations typical for each step of the disease were shown. These alterations might be of prognostic significance for evaluation of the rate of myodystrophy development.

Adolescent↗