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Biomedical subjects

I Bergström

Publications and source records attributed to I Bergström.

At least 19 recordsLinked to original sources

New mass value for 7Li.

A high-accuracy mass measurement of 7Li was performed with the SMILETRAP Penning-trap mass spectrometer via a cyclotron frequency comparison of 7Li3+ and H2+. A new atomic-mass value of 7Li has been determined to be 7.016 003 425 6(45) u with a relative uncertainty of 0.63 ppb. It has uncovered a discrepancy as large as 14sigma (1.1 microu) deviation relative to the literature value given in the Atomic-Mass Evaluation AME 2003. The importance of the improved and revised 7Li mass value, for calibration purposes in nuclear-charge radii and atomic-mass measurements of the neutron halos 9Li and 11Li, is discussed.

Journal Article↗

Determination of the (76)Ge double beta decay Q value.

The Q value of the (76)Ge double beta decay has been determined by measuring the masses of (76)Ge and (76)Se in a Penning trap using neon- and fluorinelike ions. The obtained masses are 75.921 402 758(96) u and 75.919 213 795(81) u, respectively. The systematic errors of these two determinations are nearly equal, and therefore, the remaining systematic uncertainty of the Q value is drastically reduced. A Q value of 2 039.006(50) keV was obtained improving the accuracy of the accepted value by a factor of 6.

Journal Article↗

Serum thymidine kinase in congenital dyserythropoietic anaemia type III.

Serum thymidine kinase (TK) was determined in a family with congenital dyserythropoietic anaemia type III (CDA, type III). 20 patients and 10 of their healthy siblings were investigated. Elevated TK was found in all 20 patients (median 56.2 U) but their healthy siblings had normal values (median 2.65 U). We suggest that determination of TK should be used for discrimination between healthy siblings and individuals affected by CDA type III when bone marrow examination is not suitable.

Anemia, Dyserythropoietic, Congenital↗

Intravascular haemolysis and increased prevalence of myeloma and monoclonal gammopathy in congenital dyserythropoietic anaemia, type III.

A family with congenital dyserythropoietic anaemia type III was studied. Twenty patients and 10 of their healthy siblings were clinically examined and questioned about their medical history. Blood sampling and bone marrow aspirations were also performed. Forty-five percent of the patients reported symptoms of anaemia and 35% regularly felt weakness, fatigue, or headache. However, the majority of the patients regarded themselves as healthy. The bone marrow showed a uniform picture of erythroid hyperplasia with multinuclear erythroblasts and gigantoblasts with up to 12 nuclei. There was laboratory evidence of intravascular haemolysis and mild anaemia. We also observed a high prevalence of monoclonal gammopathy of undetermined significance (3 cases) and myeloma (1 case) among the patients.

Anemia, Dyserythropoietic, Congenital↗

Familial malignant blood disease in the country of Jämtland, Sweden.

In a material of 942 patients with malignant hematological disease, encompassing all diagnosed cases in the country of Jämtland in Sweden during a 22-yr period, 36 families with multiple cases of such disease were found. Approximately 5% of the patients have at least one close relative who also suffers from a malignant hematological disease. An especially strong familial occurrence was found in the group of chronic lymphoproliferative diseases and it is concluded that this tendency comprises all diseases in the group, i.e. chronic lymphocytic leukemia, multiple myeloma and malignant lymphoma. In some families several cases of acute leukemia were present, and suggestions concerning immunological disturbances are made. In the group of chronic myeloproliferative diseases familial factors do not seem to play an important part, with the possible exception of polycythemia vera. Both heredity and common environmental agents must be considered as possible etiologic factors.

Humans↗

Comparison of acridine orange, acriflavine, and bisbenzimide stains for enumeration of bacteria in clear and humic waters.

In highly humic water, acridine orange precipitated with dissolved humic matter, resulting in such bright background fluorescence that no bacteria could be seen. With bisbenzimide staining, a similar precipitate was nonfluorescent but obscured many cells. An acriflavine staining method proved useful and reproducible both in clear and in humic waters. Fading of fluorescence was not a problem, and stained samples could be stored after preparation. The fluorescence of cells stained with acriflavine was weaker than that with acridine orange, making counting extremely small cells slightly more difficult with the former stain.

Journal Article↗

Studies of drug-treated diabetes in the county of Jämtland, Sweden, based on prescription of insulin and oral antidiabetic drugs.

Epidemiological data on drug-treated diabetes mellitus was obtained by analyzing prescriptions of insulin and oral antidiabetics in the county of Jämtland Sweden. During a 12-year period, from 1971 to 1982, the prevalence of diabetes increased from 1.5% to 2.2%, while there was no significant change in the annual incidence of around 2.7/1000 inhabitants. Women displayed a considerable higher prevalence and incidence than men in the over 70 age-group, while in the 50 - 69 age-group there was a male dominance. A significant change in the prescription pattern with an increased use of insulin and decreased use of oral antidiabetics was observed during the period. More patients were started on oral antidiabetics during the first part of the year than during the latter.

Adolescent↗