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Biomedical subjects

I Bihari

Publications and source records attributed to I Bihari.

14 recordsLinked to original sources
PubMed2001

[Thromboembolism in travelers].

The association between long haul travel and the risk of venous thromboembolism are suspected for long time. Mostly air travel related thrombosis series have been reported in the literature. Risk factors can be classified as: 1. travel related factors (coach position, immobilization, prolonged air travel, narrow seat and room, diuretic effect of alcohol, insufficient fluid intake, dehydration, direct pressure on leg veins, rare inspiration). 2. air plane related risk factors (low humidity, relative hypoxia, stress). 3. patient related factors (hereditary and acquired thrombophylia, previous deep venous thrombosis, age over 40, recent surgery or trauma, gravidity, puerperium, oestrogen containing pills, varicosity, chronic heart disease, obesity, fever, diarrhoea, vomiting, smoking). No patient related factors were found in some cases. To reduce the hazards air travellers are rightly concerned to know the level of the risk and the airlines should be responsible for this information. People should discuss with their physician what prophlylactic measures should be taken, such as compression stockings or low molecular weight heparin. Not only flight but car, bus and train travellers are also at risk of developing venous thromboembolism. Long haul travel alone is a separate risk factor for venous thromboembolism.

Humans↗
PubMed2001

Reasons for ulceration after injection treatment of telangiectasia.

BACKGROUND: Sclerotherapy of telangiectasias is widely used for their treatment, but causes skin ulceration in 0.2-1.2% of patients. The cause of this complication is still unclear. OBJECTIVE: We hypothesized that an arteriole is occluded because the sclerosant gets into an arteriovenous (AV) shunt. We have looked for these communications underneath the telangiectasias. METHODS: Doppler examination was performed in 155 cases above the telangiectasias to reveal the presence of an AV shunt. Twenty-two positive sites were excised and histologically screened for AV shunts. RESULTS: Pulsatile sound could be detected by Doppler transducer above spider veins in 112 cases (72.2%). Of the 22 Doppler-positive telangiectasias, 19 AV microshunts could be found histologically. CONCLUSIONS: Understanding the mechanism of this complication can lead to its prevention. No more than 0.2 ml of sclerosant should be administered to a single site. The warning sign of backwash of sclerosant into arterials is the temporary blanching of the skin from the arterial spasm.

Adult↗
PubMed1999

[The third venous system of the lower extremity and its clinical significance].

In deep venous thrombotic and aplasia cases superficial veins become dilated. With the resulting incompetence of the valves, venous blood stream is not directed to the heart, but to the ankle as well. In these cases the superficial system does not support the venous drainage of the limb, but gives a further load. The question is if one can ameliorate the venous drainage with removal of insufficient varicose veins, or does it make the outcome worse? A new examination was developed to determine if collateral veins in the subfascial space are enough to drain the venous blood of the limb. A tensiometer cuff was placed on the limb and inflated. The patient was asked to walk, if it was performed without complaints then the results was negative and the superficial veins were removed. In these cases no venous disturbances were detected during the operation or following that, in spite of the absence of deep venous circulation and radical removal of varicose venous bed. It means, that in the absence of deep venous circulation develops a collateral circulation not only in the subcutaneous, but in the subfascial space as well and it can alone maintain the venous drainage of the limb, this is the third venous system of the leg.

Collateral Circulation↗
PubMed1991

[Conservative management of lymphedema of the limbs].

Etiology and stadium of 63 lymphoedema patients are shown. The method of lymph-drainage therapy is discussed. Important part of this treatment is bandaging. Lymphamat pump (Bösl) was successfully used as a part of the therapy. According to the good experiences it seems to be adviceable to use this method for treatment of limb lymphoedema. This method was successful in diuretics, Venoruton, Doxium and Lymph-compress resistant cases.

Adult↗
PubMed1990

Can varicectomy be performed if deep veins are occluded?

The problem of varicectomy in the setting of deep venous occlusion is discussed. A new and simple test is applied to determine if the resulting varicosity is necessary to contribute to venous circulation in the limb and if subfascial collateral pathways are sufficient to maintain it. The test is a modification of the Perthes test. Instead of a rubber-strip tourniquet, a tensiometer cuff is used with 110 mmHg for 5 minutes on a walking patient. In negative cases the superficial varicosity can be removed radically, in spite of deep venous occlusion, to decrease the venous blood loading and ameliorate the venous drainage without risk to the blood circulation.

Adult↗
PubMed1980

First clinical experience with a new neuromuscular blocker pipecurium bromide.

The clinical trial of the new non-depolarizing muscle relaxant 2 beta,16 beta-bis-(4'-dimethyl-1'-piperazino)-3 alpha,17 beta diacetoxy-5 alpha-androstane dibromide (pipecurium bromide, RGH-1106, Arduan) was performed on 80 patients who had to undergo medium and major size intraabdominal operation on the basis of chronic surgical indication. Four types of general anaesthetic methods were applied, neuroleptanalgesia, halothane, halothane-fentanyl combination and hydroxydione. The clinical applicability of pipecurium bromide was tried to establish the dose needed for complete muscle relaxation initially and repeatedly and the effect of antagonist drugs on the muscle relaxation. We investigated the duration of the first and repeated dose of the relaxant. Heart rate and arterial blood pressure were measured, mean arterial pressure and pulse pressure were calculated. In 10 patients of the halothane group the behaviour of some haemodynamic parameters was investigated. The changes of acid base parameters, blood gases, serum electrolytes and blood sugar were also observed. The administered doses were initially 3.88 mg/h, repeated doses 2.32 mg/h, this means 0.052 mg/kg body weight initially and 0.026 mg/kg body weight repeatedly The duration of effect after the first dose was 53 min, after the repeated doses 45 min. There were no direct effects on heart rate and arterial blood pressure. It did not affect myocardial contractility or work function, there was no remarkable changes in cardiac output. There were no direct metabolic changes due to pipecurium bromide. The relaxant has no histamine releasing effect. At the end of the anaesthesia the effect can be antagonized with neostigmine. During our observations there were no side effects or allergic reactions caused by pipecurium bromide.

Adult↗
PubMed1978

Chronic cystic masthopathya: twenty-five years experience.

The pathology and clinical aspect of chronic cystic mastopathy are discussed on the basis of experience gained in 338 cases. The condition was unilateral in 88.7% and bilateral in 11.3% of the cases. More than 50% of the patients belonged into the 40 to 49 years age group. In 5.3% transformation into cancer was observed. In 25.6% of the cancer cases the matopathic change was also detected. Fifty-nine patients had to be operated twice, 26 three or more times. The operation consisted of excision; in two cases mastectomy had to be performed. Of the patients, 95% were followed up; 21% continued to complain of slight pain in the breast.

Adult↗
PubMedDate not supplied

[Varicosities as a result of acquired non-traumatic arteriovenous fistulas].

82 patients with telangiectasias of the lower extremities near the knee were examined. At the level of these telangiectasias, it was possible to hear, with the Doppler, an arterial pulse and the histological examination showed that the telangiectasias were secondary to an arterio-venous fistula. Since this shunt is not an important one, we feel that this is a micro-fistula. In most cases, telangiectasias appear at puberty or during delivery in young women. The clinical picture is not univocal and its manifestations are more less obvious. Such an arterio-venous disease is neither congenital nor traumatic; we believe it has a special origin, corresponding to an abnormal functioning of normal cutaneous arterio-venous shunts.

Adolescent↗