[Behavior of lactate-dehydrogenase isoenzymes (LDH), aspartate-aminotransferase (GOT) and aldolase in the blood plasma of children with congenital heart defects].
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Biomedical subjects
Publications and source records attributed to I Blätterlein.
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The isoenzymes of LDH (types H and M) and the isoenzymes of GOT (cytoplasma, mitochondria) were examined in 14 male patients with chronic ischaemic heart disease before, during and after operation. The present study compares them with clinical parameters. Considering the combination of the two isoenzyme ratios, it can be generalized that chronic ischaemia of the heart is characterized both by a decrease of the ratio H : M of the LDH and an increase of the ratio M : C of the LDH and an increase of the ratio M : C of the GOT. Confirming the function of the open by-pass by recoronarography, the isoenzyme values are normal both with regard to their ratio and to their absolute values.
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