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Biomedical subjects

I Brănişteanu

Publications and source records attributed to I Brănişteanu.

5 recordsLinked to original sources
PubMedDate not supplied

[A prognostic audit in colorectal cancer: between the clinical realities and the therapeutic principles].

A clinical series of 137 cases of colorectal cancer (98 + 39) was admitted in the IVth Surgical Clinic between 1987-1996 (double compared to the previous decade), consisting of 101 men and 36 women with an average age of 62. The diagnosis was established by physical examination (43 cases, most of them acutely obstructed), completed by biological, radiological and histologic examination of the surgically removed tumours. The pre- and postoperative staging revealed a large number of advanced forms: stage I--6 cases (4.3%), stage II--33 cases (263%), stage III--52 cases (36.5%) and stage IV--46 cases (32.3%). Surgery was performed on 118 patients, the tumours being removed by different types of resections according to location in 81 cases (operative rate of 86.1% and resectability rate of 59.1%, both being higher compared to the previous decade 56.8% of the surgical procedures were palliative and 41 patients (34%) underwent curative resections. The postoperative morbidity and mortality rate was 30.5% and, respectively 4.3% (5 deceased). The long-term survival followed on 44 cases revealed that only 20.3% were alive after 5 years from the operation.

Adult↗
PubMedDate not supplied

[Cervical pregnancy].

The authors report a case of cervical pregnancy in a nulliparous woman (after treatment for secondary infertility) treated systemically and locally with methotrexate. Related to the case, they make some considerations concerning early diagnosis and conservative treatment of ectopic cervical pregnancies, in order to maintain the patients' fertility. The woman presented in this case report is now 5-weeks intrauterine pregnant.

Abortifacient Agents, Nonsteroidal↗
PubMedDate not supplied

[Scintigraphy in breast cancer].

Scintigraphy was evaluated in comparison to clinical and paraclinical methods used in diagnosis of breast tumors. 32 patients with palpable breast tumors were investigated by clinical examination, ultrasound, mammography and scintigraphy. Different radiopharmaceuticals marked with 99mTc were used, having different affinity for the tumoral tissue. A Siemens Diacam gamma camera was used. Patients were submitted to dynamic study of early blood-pool and tissular phase, followed by late static incidences. Regions of interest were compared with similar areas of the contralateral breast. Conclusions were compared to histopathological diagnosis. We have calculated sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) for each of the investigation methods. The sensitivity was 80% for clinical examination, 100% for ultrasonography, 66% for mammography and 100% for scintigraphy. The specificity was 77% for clinical examination, 50% for ultrasonography, 90% for mammography and 80% for scintigraphy. PPV was 75% for clinical examination, 60% for ultrasonography, 80% for mammography and 82% for mammography. NPV was 82% for clinical examination, 100% for ultrasonography, 71% for mammography and 100% for scintigraphy. Good correlation was found between scintigraphy and histopathology. Ultrasound and mammography also confirmed, in most cases, the clinically suspected diagnosis. Including scintigraphy in the investigation protocol for breast tumors will allow a better assessment of the therapy.

Adult↗
PubMedDate not supplied

[Chronic myeloid leukemia and periurethral adenoma].

Dysectatic disturbances in leukemia patients can be determined by leukemic infiltration of the prosthate or by the evolution of a co-existing peri-urethral adenoma. Indications and results of physiotherapy and surgery are evaluated in connection with an observation of peri-urethral adenoma in a patient with chronic myeloid leukemia.

Humans↗