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Biomedical subjects

I C Onongbu

Publications and source records attributed to I C Onongbu.

2 recordsLinked to original sources

Plasma lipid changes in human malaria.

Lipid concentrations in human subjects during and after infection by Plasmodium falciparum were determined. The increase in the concentration of phospholipids and triglycerides during infection was statistically significant (p less than 0.01 for moderate infection and p less than 0.001 for severe infection) when compared with concentration after infection. The increases in these lipid levels were almost two-fold in moderate infection and three fold in severe infection. There was no significant change in the plasma cholesterol during and after infection.

Acute Disease↗

Lipoprotein fractionation by a precipitation method. A simple quantitative procedure.

A method is described for quantitation of the three major classes of serum lipoproteins. After precipitation of very low density lipoprotein (VLDL) using sodium dodecyl sulphate, the cholesterol and triglyceride content of this lipoprotein class is directly measured. In a second aliquot serum high density lipoprotein (HDL) lipids are measured after precipitation of VLDL and low density lipoprotein (LDL). LDL cholesterol and triglyceride contents are calculated by difference. The procedure requires 2 ml serum, and sensitivity is adequate to permit lipoprotein analyses on umbilical cord serum. Close agreement is observed between this precipitation method and preparative ultracentrifugation.

Adult↗