Biomedical subjects
I C Pathak
Publications and source records attributed to I C Pathak.
Spontaneous tuberculous enteroumbilical fistulas.
Gastrointestinal tuberculosis in children is an uncommon condition. Obstruction and hemorrhage are the known common complications of tuberculous enteritis. Perforation is an uncommon complication whereas tubercular enterocutaneous fistula is a still rarer complication. Five children with spontaneous tubercular enteroumbilical fistulas are being reported. All were below the age of 10 years, the youngest being 15 months old. Four children had conservative treatment with antitubercular drugs and one had exploration, resection of gut and excision of fistula. All the children who had conservative treatment survived whereas the child who underwent surgery died in the postoperative period. We feel that the conservative management is the treatment of choice in cases of established tubercular enterocutaneous fistulas.
'Abdominal cocoon'--a cause of intestinal obstruction in a 4 years old girl.
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Extrahepatic portal hypertension: a review of 70 cases.
Among 70 children with extrahepatic portal hypertension, more than 350 episodes of bleeding occurred. Of the 32 children who were not operated upon, six (19%) died of bleeding. Twelve children in the nonoperated group are thriving and well, although six of them have rebled 1-2 times. The operated group of 38 children had a total of 43 procedures. Central splenorenal and cavomesenteric anastomosis prevented further bleeding in 10 of 12 cases in which follow-up is available. Operative mortality was 24%, the majority of which were in emergency procedures.
Clinical, hormonal and ultrastructure studies of a virilizing hepatoblastoma.
Virilizing hepatoblastoma was found to be the cause of precocious puberty in a 3 1/4-year-old boy. Both human chorionic gonadotropins and alphafetoprotein in increased amounts were detected in serum and tumor tissue. These substances disappeared from the blood after removal of the tumor. Ultrastructure studies revealed the presence of dense, membrane bound, secretory granules responsible for the hormone production.
Anterior sacral meningocele: a case report.
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The uretero pelvic obstruction in children and an assessment of the anterior transperitoneal approach.
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Choledochal cyst associated with intra hepatic cysts (Caroli's disease).
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Acute intestinal obstruction in children as seen in north west India.
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Cystic partially differentiated nephroblastoma: a clinicopathologic entity in the spectrum of infantile renal neoplasia.
Three cases of cystic partially differentiated nephroblastoma (CPDN) are presented and ten cases from literature are reviewed. CPDN has been designated by various terms; it is a cystic encapsulated tumor occurring before 2 years of age. Cysts are lined by epithelium; septa of the cysts show a mixture of partially differentiated and undifferentiated metanephrogenic blastema. This histologic feature distinguishes CPDN from multilocular cyst of kidney. In seven cases simple nephrectomy, and in remaining cases nephrectomy with radiation and/or chemotherapy, had been the treatment. The disease-free interval ranged from 5 to 72 months, without reports of recurrence or metastasis. CPDN appears to take a benign course and simple nephrectomy seems to be the treatemtn of choice. However, in view of the possibility of recurrence as shown in rare instances by congenital mesoblastic nephroma, another less aggressive lesion in the spectrum of infantile renal neoplasia, regular follow up is recommended.
Amoebic liver abscess in a four-month-old infant.
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Wilms tumour with left cord metastasis.
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Toxic dilatation of colon in infants and young children.
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Gastric teratoma in a newborn baby.
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Hepatic hydatid disease in children.
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Amoebic liver abscess in children: a report of five cases.
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Acute intestinal obstruction due to gram seed. Report of a case.
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Perineal anal transplant in anorectal malformation in female patients.
Results of perineal anal transplant in 25 patients with anorectal malformations in female children have been analyzed. The present study shows that the operation is ill advised in patients with intermediate anomalies but can be undertaken safely in patients with low anomalies. In our series best results were obtained when the transplant was performed in patients who were past 5 years of age. Colostomy, though helpful in reducing the severity of the immediate complications, does not influence the late results.