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Biomedical subjects

I Carr

Publications and source records attributed to I Carr.

114 records · Page 7Linked to original sources
PubMedDate not supplied

Neoplastic invasion in experimental carcinoma of the colon: abnormal differentiation and release of mucus.

Carcinomas of the colon were induced in F344 rats with dimethylhydrazine (20 mg/kg for 12 weeks). The invasive edges of the lesions were examined with the electron microscope. As in human colorectal cancer, the invasive edges show neoplastic cells with abnormal differentiation of apical cytoplasmic rootlets and processes at the basal or invasive edge of the cell, 'apical reversal'. Mucous carcinoma cells release material into the interstitial connective tissue matrix. The features may contribute to the complex phenomenon of neoplastic invasion.

Adenoma↗
PubMedDate not supplied

Arrowroot as a treatment for diarrhoea in irritable bowel syndrome patients: a pilot study.

OBJECTIVES: Arrowroot is an old-fashioned remedy for diarrhoea, but no clinical studies have been done to evaluate its effectiveness. The aim of this pilot study was to assess its efficacy as a treatment for diarrhoea in 11 patients, all of whom had irritable bowel syndrome with diarrhoea as a feature. METHODS: The patients were interviewed and a questionnaire completed on entry into the trial. They then took 10 mL arrowroot powder three times a day for one month and discontinued the treatment for the subsequent month. Questionnaires were completed after one month on treatment and at the end of the trial after one month off treatment. RESULTS: Arrowroot reduced diarrhoea and had a long-term effect on constipation. It also eased abdominal pain. CONCLUSION: Arrowroot is an effective treatment for diarrhoea. Its action could be explained by several theories which relate to an increase in faecal bulk and thus a more efficient bowel action. The number of patients was small, and further studies are needed to substantiate preliminary results.

Adult↗
PubMedDate not supplied

"Not on the outward appearance .... but on the heart." Matthew Baillie and cardiology.

The work of Matthew Baillie (1761-1823), pathologist and physician, is presented with particular relation to the cardiovascular system. Baillie wrote the first systematic textbook of morbid anatomy in the English (or any other) language, and commissioned a book of elegant and accurate illustrations by William Clift (1775-1849). Baillie laid down the anatomical groundwork on which the subsequent generation of physicians built an accurate knowledge of cardiovascular disease. His textbook was widely translated, and influenced medical students and physicians over the first half of the 19th century. His influence on morbid anatomy was similar to that of Vesalius on the science of normal anatomy.

Cardiology↗
PubMedDate not supplied

The role of acupuncture in the treatment of irritable bowel syndrome: a pilot study.

BACKGROUND/AIMS: The aim of this pilot study was to investigate the potential value of acupuncture in the treatment of irritable bowel syndrome (IBS). METHODOLOGY: The study was an open design study of 7 patients with established irritable bowel syndrome in which assessment was by a diary card. RESULTS: The results showed a significant improvement both in general well-being and in symptoms of bloating. CONCLUSIONS: Acupuncture seems to be effective in the treatment of irritable bowel syndrome and merits further study.

Acupuncture Therapy↗