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Biomedical subjects

I Chinchón

Publications and source records attributed to I Chinchón.

26 records · Page 2Linked to original sources

[Granulomatous and allergic angiitis (Churg and Strauss). A case report (author's transl)].

The autopsy findings in a case of granulomatous and allergic angiitis, or Chung and Strauss' disease, are reported. Certain uncommon peculiarities were seen during the course of the disease, such as the presence of multiple lymph nodes presumed from a clinical standpoint to be lymphomas. Its differential diagnosis from other forms of granulomatous vasculitis, especially from those which affect the lungs preferentially or exclusively, is discussed. Special consideration is given to the limited forms of Wegener's disease, which is surprisingly similar morphologically; its more significant differences lie in the clinical and topographic areas, rather than in morphology. The lymph nodes, presumed to be lymphomas from a clinical view-point, are a truly exceptional circumstances in this disease. In the author's opinion the histologic pattern clearly indicates that the etiopathogenesis lies in a congenital or acquired immune disturbance. The recent literature is review, while the present knowledge about the broad and confusing spectrum of these conditions --arteritis, and pulmonary granulomatosis-- is discussed.

Adult↗

[Davidenkow syndrome].

A 31-year-old female had since childhood walking difficulties on her right foot. She subsequently developed a right-sided scapuloperoneal amyotrophy with mild distal sensory sings. Nerve conduction velocities and nerve biopsy showed a peripheral neuropathy, and the case was thought to be an example of Davidenkow's syndrome. At the age of 41, the musculature innervated by the right V, VII, XI and XIIth cranial nerves became impaired and this suggested that the lower motor neuron was also involved precluding this picture from inclusion among the Hereditary Motor and Sensory Neuropathies (HMSN) to which Davidenkow's syndrome has been related.

Adult↗

[Non-paraneoplastic polioencephalomyelitis].

A 60-year-old male presented with cerebellar ataxia and ocular flutter which disappeared after ten months of evolution. The patient later had three other different bouts which caused cerebral, brainstem and polyradiculoneuritis-like symptomatology. The disease evolved in 20 months and at necropsy a primary polioencephalomyelitis was found. The remitting and relapsing course of the disease is better explained by an autoimmune-mediated lesion.

Encephalomyelitis↗

[Chronic demyelinating polyneuropathy associated with multiple sclerosis: a patient with two diseases].

We studied the clinical, paraclinical and laboratory findings of a patient suffering from multiple sclerosis (MS) with chronic demyelinating polyneuropathy. As well as being a new case of demyelination of the central and peripheral nervous system not normally associated with the presence of antiganglionic antibodies, our patient presented clinical signs distinct from each disease with the characteristic abnormalities of cerebrospinal fluid (CSF) (cytological albumin dissociation at the moment when an outbreak appeared at the peripheral level and an increase in intrathecal secretion when the outbreak was at the central nervous system level). Demyelinating diseases of the central and peripheral nervous systems are a field of great interest in trying to find the antigenic bull's eye for MS.

Adult↗