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Biomedical subjects

I Csaba

Publications and source records attributed to I Csaba.

At least 37 records · Page 2Linked to original sources
PubMed1988

Screening in pregnancy with unconjugated serum estriol compared with urinary estriol.

The diagnostic value of estriol determinations in high-risk pregnancies is frequently discussed in the literature. Estriol levels of urine and serum samples of 48 asymptomatic pregnant women were analyzed using direct radioimmunoassay. A correlation was found (r = 0.5997) between urine and serum samples, nevertheless the correlation was stronger (r = 0.8278) if 4 cases with extreme deviation were omitted. In these cases the serum estriol levels were high and the urine estriol levels were low. The outcome of the pregnancies was without any complication. Our observations suggest that determination of unconjugated serum estriol levels is more reliable in the monitoring of high-risk pregnancies, since they do not depend on renal and hepatic functions.

Adult↗
PubMed1988

[Dysgerminoma of the ovary. An analysis of 30 cases].

30 patients with ovarian dysgerminoma are reported. Whenever possible the patients were operated radically. In cases when dissemination occurred, exploration was performed. 28 patients were irradiated. Applying adequate therapy, complete growths have proved to have poor prognosis.

Adolescent↗
PubMed1987

Placental protein 10: levels in benign and malignant ovarian cyst fluids and pleural exudates.

Placental protein 10 (PP10) was measured in benign (n = 47) and malignant (n = 10) ovarian cyst fluids and in pleural fluid specimens from 19 patients with pleural metastases of various carcinomas (n = 15) or infectious pleurisy (n = 4). PP10 was found in 9 out of 18 follicular or luteal cyst fluids (range 2.0-42.0 micrograms/l) and in 24 out of 29 benign ovarian tumours (range 2.6-38.0 micrograms/l). Nine out of ten malignant ovarian cyst fluids contained detectable PP10 (range 4.0-55.2 micrograms/l). PP10 was found in all the pleural fluids from 15 patients with metastatic bronchial, pulmonary, breast or pancreatic carcinomas (range 5.1-100.2 micrograms/l), as well as from four patients with pleurisy (range 5.0-28.6 micrograms/l). Our results indicate that PP10 is tumour-associated, but not tumour-specific.

Female↗
PubMed1987

The effect of Danazol on the circulating levels of 34K insulin-like growth factor-binding protein (PP12) and endometrial secretory protein PP14.

Twenty-four women, 11 with endometriosis and 13 with fibrocystic mastopathy, were treated with a medium dose (300-400 mg daily) of Danazol for 6 months. The circulating level of progesterone, the 34K insulin-like growth factor-binding protein (IGF-bp) and endometrial protein PP14 (placental protein 14) were measured by specific radioimmunoassays before and during treatment. The serum progesterone concentration decreased significantly during Danazol treatment, as did the serum levels of 34K IGF-bp and PP14. By the third month of therapy amenorrhoea was observed in 22 out of 24 women and this was accompanied by a further decline in the IGF-bp and PP14 levels. In light of the previous observations on the IGF-bp and PP14 synthesis by secretory endometrium and the fact that Danazol causes endometrial atrophy, these results suggest that Danazol treatment has an effect on endometrial protein secretion.

Adult↗
PubMed1987

Placental protein 5 in benign and malignant ovarian cyst fluids.

Placental protein 5 (PP5), a serine protease inhibitor, was measured by radioimmunoassay in fluids aspirated from benign and malignant cystic ovarian tumours. PP5 was found in 7 out of 9 malignant and in 12 out of 29 benign cyst fluids (p less than 0.01), the levels ranging from 3.0 to 73.4 micrograms/l. No PP5 was found in the corresponding serum samples from 4 patients whose malignant cystadenocarcinomas contained PP5. In those tumours where PP5 was found, no difference was observed in the PP5 levels between benign and malignant, or between serous and mucinous tumours.

Female↗